Abstract: The present invention relates to a preparation method of a carrier containing a radiolabeled colloid, which comprises the following steps: adsorption: putting a carrier into a radioisotope water solution, and reacting for 5-20 minutes to obtain a first solution; coating: adding a solvent capable of enabling a colloid to be formed into the first solution, and reacting for 5-20 minutes to obtain a second solution; and purification: centrifuging the second solution to form a first supernatant and a first precipitate, removing the first supernatant, cleaning the first precipitate with deionized water, centrifuging to form a second supernatant and a second precipitate, and finally, removing the second supernatant, wherein the residual second precipitate is the carrier containing the radiolabeled colloid.

Abstract: Disclosed herein are a multi-functional probe and uses thereof. The multi-functional probe has a main structure represented by chemical Formula (1), and is configured to diagnose and treat the cancers.

Abstract: The present invention relates to an automatic system for synthesizing iodine-123 meta-iodobenzylguanidine (123I-MIBG), which comprises a first reactor for subjecting radioactive iodine-containing sodium iodide and meta-iodobenzylguanidine (MIBG) sulfate to an iodine-iodine exchange reaction to obtain radioactive iodine labeled MIBG; a purification unit for purifying the iodine labeled MIBG; and a second reactor for substituting a solvent used in purification with a phosphate buffer to obtain a phosphate solution containing 123I-MIBG. The present invention also relates to an automatic device for dispensing 123I-MIBG, which comprises the automatic system for synthesizing 123I-MIBG, a radioactivity measuring unit, and a dispensing and packing unit.

Abstract: The present invention relates to a biodegradable carrier for carrying a radioisotope, which is formed from at least one biodegradable polymer selected from the group consisting of poly(lactic-co-glycolic acid) (PLGA), poly(lactic acid) (PLA), poly(?-caprolactone) (PCL), chitosan, poly(?-glutamic acid) (PGA), and polyethylene glycol (PE) in which its hydroxyl group is substituted with an amino group and grafted with tetraazocyclododecanetetraacetic acid monosuccinimide ester (DOTA-NHS), in which nitrogen atoms contained in the DOTA-NHS are provided for coordinating with a radioisotope. The present invention also relates to a kit which includes a first container containing the biodegradable carrier for carrying a radioisotope according to the present invention and a second container containing a radioisotope.

Abstract: The present invention relates to an automatic system for synthesizing iodine-123 meta-iodobenzylguanidine (123I-MIBG), which comprises a first reactor for subjecting radioactive iodine-containing sodium iodide and meta-iodobenzylguanidine (MIBG) sulfate to an iodine-iodine exchange reaction to obtain radioactive iodine labeled MIBG; a purification unit for purifying the iodine labeled MIBG; and a second reactor for substituting a solvent used in purification with a phosphate buffer to obtain a phosphate solution containing 123I-MIBG. The present invention also relates to an automatic device for dispensing 123I-MIBG, which comprises the automatic system for synthesizing 123I-MIBG, a radioactivity measuring unit, and a dispensing and packing unit.

Abstract: A thermosensitive hydrogel for coating radioisotopes and chemotherapeutic agents to treat cancer and a method for preparing the same are revealed. The anticancer drugs such as radiopharmaceuticals or chemotherapeutic agents are coated with the hydrogel formed by PCL-PEG-PCL. By the feature of the hydrogel body that changes from liquid phase at low storage temperature to gel form at body temperature, not only the anticancer drugs can be injected into the human body and reaching the treatment site smoothly but the treatment time of brachytherapy is also extended. Thus the side effects of cancer therapy are significantly reduced.