Patents by Inventor Ying Kan

Ying Kan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20260125424
    Abstract: A bioactive peptide PCT-1, and preparation method and application thereof are provided. The amino acid sequence of the bioactive peptide PCT-1 is LNRTFE, as shown in SEQ ID NO: 1, and the bioactive peptide PCT-1 has antioxidant and intestinal flora-regulating functions. Extracted from spirulina protein peptides, the bioactive peptide PCT-1 can significantly increase the activities of SOD and GSH-Px in serum, and significantly reduce the content of MDA in serum; its in vivo antioxidant activity is comparable to that of the positive control Trolox. Meanwhile, compared with the blank control group, the bioactive peptide PCT-1 can also reduce the ?-diversity index of intestinal flora, change the overall structure of intestinal flora, regulate the abundance of intestinal flora at various taxonomic levels, and significantly increase the contents of acetic acid and butyric acid. Therefore, the bioactive peptide PCT-1 can be applied in functional foods for antioxidation and intestinal flora regulation.
    Type: Application
    Filed: December 30, 2025
    Publication date: May 7, 2026
    Applicants: YANTAI INST COASTAL ZONE RES CAS, YANTAI ZHIGONG BIOMEDICAL TECH CO LTD
    Inventors: Wenjun LI, Tuanjie CHE, Song QIN, Chenyang LU, Jinzhang XU, Libo YAN, Guizhen XIE, Ying KAN
  • Patent number: 12450316
    Abstract: A method, a system, a medium and a device based on multi-spectral data fusion are provided. The method includes: collecting spectrum: collecting NIR spectrum and MIR spectrum of a substance to be detected to obtain a NIR spectrum matrix and a MIR spectrum matrix of the substance to be detected; constructing a detection model; training the detection model; and predicting detection indexes.
    Type: Grant
    Filed: June 18, 2025
    Date of Patent: October 21, 2025
    Assignee: National Institute of Metrology China
    Inventors: Ying Kan, Ke Li, Zhengdong Zhang, Dan Song, Xin Zhang, Chaomin Ding, Fan Liu, Qi Li
  • Patent number: 8974785
    Abstract: The invention provides a fully human anti-HER2 monoclonal antibody, which has an amino acid sequence of heavy chain variable region as shown in SEQ ID NO: 6 and an amino acid sequence of light chain variable region as shown in SEQ ID NO: 8. The invention also discloses the nucleotide sequence encoding the antibody, the expression vector and the host cell comprising the nucleotide sequence, and the use of the antibody for manufacturing the medicament for the treatment of tumor.
    Type: Grant
    Filed: April 16, 2010
    Date of Patent: March 10, 2015
    Assignee: Shanghai Biomabs Pharmaceuticals Co., Ltd.
    Inventors: Chuan Li, Xin Tong, Ying Kan
  • Patent number: 8664368
    Abstract: The present invention provides a fully human anti-VEGF monoclonal antibody, the preparation method and use thereof. The fully human anti-VEGF monoclonal antibody is obtained by using antibody phage display technology, which has higher antibody affinity and stronger capacity for inhibiting tumor cell proliferation in comparison with humanized antibody bevacizumab, and can be used to prepare anti-tumor medicines.
    Type: Grant
    Filed: April 16, 2010
    Date of Patent: March 4, 2014
    Assignee: Shanghai Biomabs Pharmaceuticals Co., Ltd.
    Inventors: Shuhui Wang, Chuan Li, Ying Kan, Xin Tong
  • Publication number: 20130046081
    Abstract: The present invention provides a fully human anti-VEGF monoclonal antibody, the preparation method and use thereof. The fully human anti-VEGF monoclonal antibody is obtained by using antibody phage display technology, which has higher antibody affinity and stronger capacity for inhibiting tumor cell proliferation in comparison with humanized antibody bevacizumab, and can be used to prepare anti-tumor medicines.
    Type: Application
    Filed: April 16, 2010
    Publication date: February 21, 2013
    Applicant: Shanghai Biomabs Pharmaceuticals Co., LTD
    Inventors: Shuhui Wang, Chuan Li, Ying Kan, Xin Tong
  • Publication number: 20120309942
    Abstract: The invention provides a fully human anti-HER2 monoclonal antibody, which has an amino acid sequence of heavy chain variable region as shown in SEQ ID NO: 6 and an amino acid sequence of light chain variable region as shown in SEQ ID NO: 8. The invention also discloses the nucleotide sequence encoding the antibody, the expression vector and the host cell comprising the nucleotide sequence, and the use of the antibody for manufacturing the medicament for the treatment of tumor.
    Type: Application
    Filed: April 16, 2010
    Publication date: December 6, 2012
    Applicant: Shanghai Biomabs Pharmaceuticals Co., LTD.
    Inventors: Chuan Li, Xin Tong, Ying Kan
  • Publication number: 20120071480
    Abstract: This invention relates to novel compounds having the formula (I): and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment for cancer.
    Type: Application
    Filed: December 1, 2011
    Publication date: March 22, 2012
    Inventors: Xiaomei Feng, Huiping Guan, Stephanos Ioannidis, Bo Peng, Mei Su, Tao Wang, Hai-Jun Zhang, Ying Kan, Bin Wang
  • Publication number: 20100160325
    Abstract: This invention relates to novel compounds having the formula (I) and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment for cancer.
    Type: Application
    Filed: February 26, 2010
    Publication date: June 24, 2010
    Applicant: ASTRAZENECA AB
    Inventors: Xiaomei Feng, Huiping Guan, Stephanos Ioannidis, Bo Peng, Mei Su, Tao Wang, Hai-Jun Zhang, Ying Kan, Bin Wang
  • Publication number: 20080287475
    Abstract: This invention relates to novel compounds having the formula (I) and to their pharmaceutical compositions and to their methods of use. These novel compounds provide a treatment for cancer.
    Type: Application
    Filed: October 26, 2006
    Publication date: November 20, 2008
    Applicant: ASTRAZENECA AB
    Inventors: Xiaomei Feng, Huiping Guan, Ying Kan, Stephanos Ioannidis, Bo Peng, Mei Su, Bin Wang, Tao Wang, Hai-Jun Zhang