Patents by Inventor YING-SHUAN LAILEE

YING-SHUAN LAILEE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibody-drug conjugates containing an anti-mesothelin antibody and uses thereof
    Patent number: 11998613
    Abstract: The present disclosure provides an immunoconjugate includes an antibody comprising an antigen-binding fragment that specifically binds to an epitope in mesothelin, N-glycan binding domain and an N-glycan; a linker linking to the N-glycan; and a payload A and a payload B conjugated to the linker, respectively; wherein the payload A and the payload B are the same or different. A pharmaceutical composition comprises the immunoconjugate and a method for treating cancer are also provided in the disclosure.
    Type: Grant
    Filed: June 4, 2021
    Date of Patent: June 4, 2024
    Assignee: DEVELOPMENT CENTER FOR BIOTECHNOLOGY
    Inventors: Shih-Hsien Chuang, Wei-Ting Sun, Ying-Shuan Lailee, Chun-Liang Lai, Wun-Huei Lin, Win-Yin Wei, Shih-Chong Tsai, Cheng-Chou Yu, Chao-Yang Huang
  • ANTIBODY-DRUG CONJUGATES CONTAINING AN ANTI-MESOTHELIN ANTIBODY AND USES THEREOF
    Publication number: 20210386866
    Abstract: The present disclosure provides an immunoconjugate includes an antibody comprising an antigen-binding fragment that specifically binds to an epitope in mesothelin, N-glycan binding domain and an N-glycan; a linker linking to the N-glycan; and a payload A and a payload B conjugated to the linker, respectively; wherein the payload A and the payload B are the same or different. A pharmaceutical composition comprises the immunoconjugate and a method for treating cancer are also provided in the disclosure.
    Type: Application
    Filed: June 4, 2021
    Publication date: December 16, 2021
    Applicant: DEVELOPMENT CENTER FOR BIOTECHNOLOGY
    Inventors: SHIH-HSIEN CHUANG, WEI-TING SUN, YING-SHUAN LAILEE, CHUN-LIANG LAI, WUN-HUEI LIN, WIN-YIN WEI, SHIH-CHONG TSAI, CHENG-CHOU YU, CHAO-YANG HUANG