Patents by Inventor Ying-Ting Wang

Ying-Ting Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12152250
    Abstract: A method for activating and expanding isolated T cells, the method including adding to isolated T cells ligands presenting microbubbles having a flexible lipid shell with an inner bubble wall enclosing a gas and an outer bubble wall conjugated to ligands capable of achieving cell contact dependent juxtacrine signaling on the isolated T cells; and adding to isolated T cells ligands presenting microbubbles having a flexible lipid shell with an inner bubble wall enclosing a gas and an outer bubble wall conjugated to an antigen capable of forming an immunological synapse (IS) with the T cells.
    Type: Grant
    Filed: September 26, 2019
    Date of Patent: November 26, 2024
    Assignee: DIAGNOLOGIX, LLC
    Inventors: Guixin Shi, Kimberly Liu, Ying-Ting Wang
  • Publication number: 20200017830
    Abstract: A method for activating and expanding isolated T cells, the method including adding to isolated T cells ligands presenting microbubbles having a flexible lipid shell with an inner bubble wall enclosing a gas and an outer bubble wall conjugated to ligands capable of achieving cell contact dependent juxtacrine signaling on the isolated T cells; and adding to isolated T cells ligands presenting microbubbles having a flexible lipid shell with an inner bubble wall enclosing a gas and an outer bubble wall conjugated to an antigen capable of forming an immunological synapse (IS) with the T cells.
    Type: Application
    Filed: September 26, 2019
    Publication date: January 16, 2020
    Inventors: Guixin Shi, Kimberly Liu, Ying-Ting Wang
  • Patent number: 10479976
    Abstract: A buoyancy enabled separation method for isolation from a sample including a variety of different cells a sparse subset of cells that is differentiated by a plurality of different cell surface markers. Microbubbles conjugated to antibodies are applied sequentially in a container with the previously used microbubbles disrupted prior to applying the next microbubbles conjugated to a different antibody. A system that includes a syringe-like container with a plunger and closeable opening. Further, a method for activating and expanding isolated T cells by applying antigen presenting microbubbbles having a flexible lipid shell mimicking an antigen presenting cell for generating immunological synapses.
    Type: Grant
    Filed: December 14, 2017
    Date of Patent: November 19, 2019
    Assignee: Diagnologix, LLC
    Inventors: Guixin Shi, Kimberly Liu, Ying-Ting Wang
  • Publication number: 20180171295
    Abstract: A buoyancy enabled separation method for isolation from a sample including a variety of different cells a sparse subset of cells that is differentiated by a plurality of different cell surface markers. Microbubbles conjugated to antibodies are applied sequentially in a container with the previously used microbubbles disrupted prior to applying the next microbubbles conjugated to a different antibody. A system that includes a syringe-like container with a plunger and closeable opening. Further, a method for activating and expanding isolated T cells by applying antigen presenting microbubbbles having a flexible lipid shell mimicking an antigen presenting cell for generating immunological synapses.
    Type: Application
    Filed: December 14, 2017
    Publication date: June 21, 2018
    Inventors: Guixin Shi, Kimberly Liu, Ying-Ting Wang