Patents by Inventor Ying-Wen Shen
Ying-Wen Shen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220204936Abstract: A non-fibrous film of which the composition includes a collagen and a polyester polymer is provided. A content of the polyester polymer in the non-fibrous film is 1-60 wt %. Moreover, the non-fibrous film has a swelling rate of 1-200 ?m/hour or a swelling proportion per unit time of 0.1-2%/hour in an aqueous liquid.Type: ApplicationFiled: September 15, 2021Publication date: June 30, 2022Applicant: Industrial Technology Research InstituteInventors: Yu-Bing LIOU, Chih-Ching LIAO, Hsin-Yi HSU, Ying-Wen SHEN, Yun-Chung TENG, Hsin-Hsin SHEN, Yi-Chen CHEN
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Publication number: 20220204772Abstract: A bioprintable material is provided. The bioprintable material includes a hydrogel and microfilaments mixed in the hydrogel. The hydrogel includes a first collagen. The microfilament includes a second collagen. The diameter of the microfilament is ranging from 5 microns to 200 microns. The weight ratio of the microfilaments to the first collagen is ranging from 0.01:1 to 10:1.Type: ApplicationFiled: December 23, 2021Publication date: June 30, 2022Applicant: Industrial Technology Research InstituteInventors: Yun-Chung TENG, Jen-Huang HUANG, Ying-Wen SHEN, Yu-Bing LIOU, Hsin-Yi HSU, Li-Hsin LIN, Yuchi WANG, Hsin-Hsin SHEN
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Patent number: 11254902Abstract: A cell culture module, a cell culture system and a cell culture method are provided. The cell culture module includes a casing, a first fixer, a second fixer and a sheet-shaped carrier member. The casing has a chamber and at least one inlet/outlet. The inlet/outlet communicates with the chamber. The first fixer is fixed to the casing and located in the chamber. The second fixer is disposed in the chamber and is movable relative to the first fixer. The sheet-shaped carrier member is formed by arranging a plurality of cell culture carriers, and two opposite ends of the sheet-shaped carrier member are respectively fixed to the first fixer and the second fixer. The sheet-shaped carrier member is in an open state or a folded state according to a variation in a distance between the first fixer and the second fixer due to a movement of the second fixer.Type: GrantFiled: December 20, 2018Date of Patent: February 22, 2022Assignee: Industrial Technology Research InstituteInventors: Ing-Kae Wang, Ying-Wen Shen, Yea-Tzy Deng, Den-Tai Lin, Yu-Bing Liou, Sing-Ying Hsieh, Wei-Zhou Yeh, Meng-Hua Yang, Hsiang-Chun Hsu, Ying-Chun Chien
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Patent number: 11154637Abstract: A biodegradable sealant includes: a polyethylene glycol derivative; a photoinitiator; and a solvent, wherein the content of the polyethylene glycol derivative is about 10-75 wt % in the biodegradable sealant. The polyethylene glycol derivative is obtained by a substitution reaction, and in the substitution reaction, the polyethylene glycol is modified with methacrylic anhydride.Type: GrantFiled: November 6, 2019Date of Patent: October 26, 2021Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Hsin-Hsin Shen, Yu-Chi Wang, Sen-Lu Chen, Yu-Bing Liou, Jian-Wei Lin, Yi-Hsuan Lee, Ming-Chia Yang, Ying-Wen Shen, Wei-Lin Yu
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Patent number: 11103446Abstract: An ophthalmic drug delivery device and a method for fabricating the same are provided. The ophthalmic drug delivery device includes a shield element and a drug release element. The shield element has a light transmittance more than or equal to 80%. The drug release element is an annular body so that the drug release element surrounds the shield element. The drug release element is neutral and includes a cross-linked neutral collagen, a first hydrophilic biodegradable polymer and a drug. The shield element is acidic and includes a cross-linked acidic collagen and a second hydrophilic biodegradable polymer.Type: GrantFiled: December 31, 2019Date of Patent: August 31, 2021Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Yu-Bing Liou, Hsin-Yi Hsu, Ying-Wen Shen, Yun-Chung Teng, Yuchi Wang, Hsin-Hsin Shen
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Publication number: 20210206064Abstract: A three-dimensional printing apparatus having electrostatic auxiliary, including a printing platform, a feeding device, a nozzle, and a high voltage power supply, is provided. The feeding device and the nozzle are disposed above the printing platform. The nozzle is connected to the feeding device and is located between the feeding device and the printing platform. A distance between the nozzle and the printing platform is less than or equal to 1 cm. The high voltage power supply has an output end electrically connected to the nozzle and a ground end electrically connected to the printing platform.Type: ApplicationFiled: December 22, 2020Publication date: July 8, 2021Applicant: Industrial Technology Research InstituteInventors: Hsin-Hsin Shen, Chang-Chou Li, Li-Wen Lai, Yu-Bing Liou, Ying-Wen Shen
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Publication number: 20210196626Abstract: An ophthalmic drug delivery device and a method for fabricating the same are provided. The ophthalmic drug delivery device includes a shield element and a drug release element. The shield element has a light transmittance more than or equal to 80%. The drug release element is an annular body so that the drug release element surrounds the shield element. The drug release element is neutral and includes a cross-linked neutral collagen, a first hydrophilic biodegradable polymer and a drug. The shield element is acidic and includes a cross-linked acidic collagen and a second hydrophilic biodegradable polymer.Type: ApplicationFiled: December 31, 2019Publication date: July 1, 2021Applicant: Industrial Technology Research InstituteInventors: Yu-Bing LIOU, Hsin-Yi HSU, Ying-Wen SHEN, Yun-Chung TENG, Yuchi WANG, Hsin-Hsin SHEN
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Publication number: 20210147789Abstract: A cell recovery method including the following steps is provided. A cell culture carrier module is provided. The cell culture carrier module includes at least one cell culture carrier. The cell culture carrier is compressed into a first structure. Cell culture is performed by using the cell culture carrier exhibiting the first structure. The cell culture carrier is stretched from the first structure to a second structure. The first structure and the second structure are different structures. Cell recovery is performed by using the cell culture carrier exhibiting the second structure.Type: ApplicationFiled: January 28, 2021Publication date: May 20, 2021Applicant: Industrial Technology Research InstituteInventors: Hsiu-Ying Wang, Ying-Wen Shen, Ing-Kae Wang, Shu-Fen Yeh, Wei-Zhou Yeh
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Patent number: 10704017Abstract: A cell culture carrier module and a cell culture system having the same are provided. A cell tank and a culture medium module respectively communicate with the carrier module. The carrier module includes a reactor, a first fixer, a second fixer and a plurality of cell culture carriers. The reactor has a chamber and at least one inlet/outlet. The inlet/outlet communicates with the chamber. The first fixer is fixed to the reactor and located in the chamber. The second fixer is disposed in the chamber and is movable relative to the first fixer. Two ends of each cell culture carrier are fixed to the first fixer and the second fixer, respectively. The cell culture carriers are in an untwisted state or a twisted state according to a variation in a distance between the first fixer and the second fixer due to a movement of the second fixer.Type: GrantFiled: December 27, 2017Date of Patent: July 7, 2020Assignee: Industrial Technology Research InstituteInventors: Ying-Wen Shen, Ing-Kae Wang, Chia-Jung Lu, Yea-Tzy Deng, Yu-Bing Liou, Sing-Ying Hsieh, Hsin-Hsin Shen, Hsiu-Ying Wang
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Publication number: 20200197563Abstract: A biodegradable sealant includes: a polyethylene glycol derivative; a photoinitiator; and a solvent, wherein the content of the polyethylene glycol derivative is about 10-75 wt % in the biodegradable sealant. The polyethylene glycol derivative is obtained by a substitution reaction, and in the substitution reaction, the polyethylene glycol is modified with methacrylic anhydride.Type: ApplicationFiled: November 6, 2019Publication date: June 25, 2020Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Hsin-Hsin SHEN, Yu-Chi WANG, Sen-Lu CHEN, Yu-Bing LIOU, Jian-Wei LIN, Yi-Hsuan LEE, Ming-Chia YANG, Ying-Wen SHEN, Wei-Lin YU
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Publication number: 20200170838Abstract: An eye wearing device is provided, including a body, at least one reservoir and at least one microchannel. The body has a first surface, a second surface, a center, a first outer edge of the first surface and a second outer edge of the second surface. The reservoir is disposed in the body to load the drug. The microchannel is disposed near the first outer edge of the first surface and the second outer edge of the second surface. One end of the microchannel is connected to the reservoir for filling the drug into the reservoir. The other end of the microchannel is an opening facing an edge of the eye wearing device for contacting the cornea and/or the sclera, and the opening is connected to the first outer edge of the first surface and the second outer edge of the second surface.Type: ApplicationFiled: November 14, 2019Publication date: June 4, 2020Applicant: Industrial Technology Research InstituteInventors: Yun-Chung Teng, Yu-Bing Liou, Hsin-Yi Hsu, Ying-Wen Shen, Sen-Lu Chen, Yu-Chi Wang, Hsin-Hsin Shen
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Publication number: 20200139003Abstract: A biodegradable sealant includes: a polyethylene glycol derivative; a photoinitiator; and a solvent, wherein the content of the polyethylene glycol derivative is about 10-75 wt % in the biodegradable sealant. The polyethylene glycol derivative is obtained by a substitution reaction, and in the substitution reaction, the polyethylene glycol is modified with methacrylic anhydride.Type: ApplicationFiled: February 27, 2019Publication date: May 7, 2020Applicant: Industrial Technology Research InstituteInventors: Hsin-Hsin SHEN, Yu-Chi WANG, Sen-Lu CHEN, Yu-Bing LIOU, Jian-Wei LIN, Yi-Hsuan LEE, Ming-Chia YANG, Ying-Wen SHEN, Wei-Lin YU
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Publication number: 20190203165Abstract: A cell culture module, a cell culture system and a cell culture method are provided. The cell culture module includes a casing, a first fixer, a second fixer and a sheet-shaped carrier member. The casing has a chamber and at least one inlet/outlet. The inlet/outlet communicates with the chamber. The first fixer is fixed to the casing and located in the chamber. The second fixer is disposed in the chamber and is movable relative to the first fixer. The sheet-shaped carrier member is formed by arranging a plurality of cell culture carriers, and two opposite ends of the sheet-shaped carrier member are respectively fixed to the first fixer and the second fixer. The sheet-shaped carrier member is in an open state or a folded state according to a variation in a distance between the first fixer and the second fixer due to a movement of the second fixer.Type: ApplicationFiled: December 20, 2018Publication date: July 4, 2019Applicant: Industrial Technology Research InstituteInventors: Ing-Kae Wang, Ying-Wen Shen, Yea-Tzy Deng, Den-Tai Lin, Yu-Bing Liou, Sing-Ying Hsieh, Wei-Zhou Yeh, Meng-Hua Yang, Hsiang-Chun Hsu, Ying-Chun Chien
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Publication number: 20180223238Abstract: A cell culture carrier module and a cell culture system having the same are provided. A cell tank and a culture medium module respectively communicate with the carrier module. The carrier module includes a reactor, a first fixer, a second fixer and a plurality of cell culture carriers. The reactor has a chamber and at least one inlet/outlet. The inlet/outlet communicates with the chamber. The first fixer is fixed to the reactor and located in the chamber. The second fixer is disposed in the chamber and is movable relative to the first fixer. Two ends of each cell culture carrier are fixed to the first fixer and the second fixer, respectively. The cell culture carriers are in an untwisted state or a twisted state according to a variation in a distance between the first fixer and the second fixer due to a movement of the second fixer.Type: ApplicationFiled: December 27, 2017Publication date: August 9, 2018Applicant: Industrial Technology Research InstituteInventors: Ying-Wen Shen, Ing-Kae Wang, Chia-Jung Lu, Yea-Tzy Deng, Yu-Bing Liou, Sing-Ying Hsieh, Hsin-Hsin Shen, Hsiu-Ying Wang
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Publication number: 20170166859Abstract: A cell culture carrier module, a bioreactor and a cell recovery method are provided. The cell culture carrier module includes at least one cell culture carrier capable of transforming between a two dimensional structure and a three dimensional structure. The cell culture carrier exhibits the two dimensional structure in a loosened state and exhibits the three dimensional structure in a compressed state.Type: ApplicationFiled: December 30, 2015Publication date: June 15, 2017Inventors: Hsiu-Ying Wang, Ying-Wen Shen, Ing-Kae Wang, Shu-Fen Yeh, Wei-Zhou Yeh
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Publication number: 20160015852Abstract: According to embodiments, a composite material is disclosed. The composite material has a multi-layered structure, wherein the multi-layered structure is constituted by a hydrophilic biodegradable polymer and a collagen. In particular, the collagen is strip-shaped and has a fiber length from 1.5 mm to 50 mm. There are at least ten stacked layers per 5 ?m of thickness in the multi-layered structure.Type: ApplicationFiled: July 14, 2015Publication date: January 21, 2016Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Yu-Bing LIOU, Hsiu-Ying WANG, Hsin-Hsin SHEN, Ying-Wen SHEN, Chin-Tsung HUANG, Hsin-Yi HSU
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Publication number: 20130172946Abstract: An implant module for dragging a bone fragment toward a bone is provided. The bone fragment has a first through hole, and the bone has a second through hole. The implant module includes a screw and a stud. The screw has a first section fixed to the bone fragment and a second section provided with a first external thread on its outer surface. The stud is provided with a second external thread on its outer surface for being screwed into the second through hole of the bone. An end of the stud has a screw hole for being screwed with the second section of the screw via the first external thread. A method of repairing avulsion fracture by using the implant module is further provided.Type: ApplicationFiled: August 3, 2012Publication date: July 4, 2013Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Ching-Chuan Jiang, Chun-Jen Liao, Wen-Hsiang Chang, Shih-Jui Han, Yu-Ming Wang, Ying-Wen Shen