Abstract: Disclosed are a display panel and a method of manufacturing a display panel. The display panel includes an array substrate; a color film substrate disposed opposite to the array substrate; a liquid crystal layer disposed between the array substrate and the color film substrate; a reflective layer disposed on a side of the array substrate facing the liquid crystal layer. The reflective layer comprises a plurality of first convex structures, each of the first convex structures has a first sidewall extending from a bottom to a top of each of the first convex structures, and an angle between a normal line of the first sidewall and a horizontal plane is greater than 0° and less than or equal to 10°.

Abstract: A liquid crystal display panel, a driving method, and a terminal thereof are disclosed. The display panel includes a pixel structure including data lines and scan lines, wherein each data line is connected to at least two pixel groups, and each pixel group includes three sub-pixels having different colors sequentially connected to the data lines; and a first driving unit electrically connected to the scan lines and inputting scan signals to the scan lines in a preset order to solve a problem of horizontal bright and dark lines.

Abstract: The present invention provides a novel bispecific anti-CD3/CD20 polypeptide complex formulation containing a first antigen-binding portion and a second antigen-binding portion. Specifically, the formulation comprises a liquid formulation and a lyophilized formulation.

Abstract: The invention relates to anti-CD98 antibodies and antibody drug conjugates (ADCs), including compositions and methods of using said antibodies and ADCs.

Abstract: Disclosed herein are methods to reliably and robustly generate a pure population of airway basal cells that are capable of producing a normal mucociliary epithelium. Such basal cells may be used to treat chronic respiratory diseases, such as cystic fibrosis, chronic obstructive pulmonary disease, and asthma.

Abstract: The invention relates to anti-CD98 antibodies and antibody drug conjugates (ADCs), including compositions and methods of using said antibodies and ADCs.

Abstract: Disclosed is a multi-view fast photographing device for horny jaws of cephalopods. The device includes a cover, a cover pin, a stylus, an image generating device, a data display device, and an image acquisition and processing device; a top of the image generating device is open and provided with mounting holes, and the cover is connected with the mounting holes through the cover pin and movably covers the top of the image generating device. The image acquisition and processing device is fixed at a bottom of the image generating device. The data display device is fastened to a front side wall of the image generating device. A magnetic patch is fixed on a front surface of a baffle of the data display device. The stylus is magnetically attracted to the magnetic patch.

Abstract: Disclosed herein are multivalent and multispecific binding proteins, methods of making the binding proteins, and their uses in the diagnosis, monitoring, inhibition, prevention and/or treatment of cancers, tumors, and/or other angiogenesis-dependent diseases diseases characterized by aberrant DLL4 and/or VEGF expression or activity.

Abstract: Provided are a fusion protein targeting PD-L1 and TGF-? and use thereof. The fusion protein is a fusion protein comprising an antibody or antigen-binding fragment that specifically binds to human PD-L1 and a human TGF?RII binding domain. Further provided are a polynucleotide encoding the fusion protein, a host cell containing the polynucleotide, and the use of the fusion protein in the preparation of an anti-tumor drug.

Abstract: DLL4 binding proteins are described herein, including antibodies, CDR-grafted antibodies, humanized antibodies, and DLL4 binding fragments thereof, proteins that bind DLL4 with high affinity, and DLL4 binding proteins that neutralize DLL4 and/or VEGF activity. The DLL4 binding proteins are useful for treating or preventing cancers and tumors and especially for treating or preventing tumor angiogenesis.

Abstract: Improved DLL4 binding proteins are described, including antibodies, CDR-grafted antibodies, human antibodies, and DLL4 binding fragments thereof, proteins that bind DLL4 with high affinity, and DLL4 binding proteins that neutralize DLL4 activity. The DLL4 binding proteins are useful for treating or preventing cancers and tumors and especially for treating or preventing tumor angiogenesis, and/or other angiogenesis-dependent diseases such as ocular neovascularization, or angiogenesis-independent diseases characterized by aberrant DLL4 expression or activity such as autoimmune disorders including multiple sclerosis.

Abstract: The invention is in the field of antibody formulations, and particularly relates to a pharmaceutical composition of a humanized monoclonal anti-PD-L1 antibody, wherein the pharmaceutical composition comprises 1-150 mg/ml of the humanized monoclonal anti-PD-L1 antibody, a buffer at 3-50 mM, 2-150 mg/ml of an isotonic adjuster/stabilizer and 0.01-0.8 mg/ml of a surfactant, and has a pH of about 4.5-6.8. The formulations prevent antibody aggregates therein from increasing, while enabling better maintenance of the biological binding activity of the antibody for a long time.

Abstract: A graded pressure drop type multi stage water injection device and method based on fracture observation. The device includes a test probe, a propulsion system and a control system. The test probe includes a plugging device, a pressure conversion assembly and a connected pipe. The rubber bag is wrapped around the outer end of the water leakage pipe, is fixed to both ends of the joints through a fastening iron ring and forms a blocked cavity with the water leakage pipe. The device integrates the plugging and detection system, and uses the same external water source to operate the plugging process and detection process under their respective pressures, thereby making pressure conversion more stable, solving the problem of winding the drill pipe and the hose in the propulsion process, realizing multi stage measurement in each propulsion and improving measurement efficiency.

Abstract: Within the technical field of detecting a mining-induced failure range of rock mass, and particularly relating to a graded-pressure drop type detection system and detection method of borehole cracks, a detection system is provided including a test probe, a drilling rig, a drill pipe and a control operation platform. The test probe includes a plugging device and a pressure conversion assembly. The pressure conversion assembly is connected with the plugging device at the rear end through a connected pipe and includes a first stage pressure converting device and a second stage pressure converting device. The detection system simplifies the existing operating system, avoids the problem of drill pipes winding in drill hole, realizes plugging process and detection process with the same external water source, and ensures that the plugging process and the observation process operate under respective predetermined pressures.

Abstract: The invention relates to anti-CD98 antibodies and antibody drug conjugates (ADCs), including compositions and methods of using said antibodies and ADCs.

Abstract: The invention relates to anti-CD98 antibodies and antibody drug conjugates (ADCs), including compositions and methods of using said antibodies and ADCs.

Abstract: The invention relates to anti-CD98 antibodies and antibody drug conjugates (ADCs), including compositions and methods of using said antibodies and ADCs.

Abstract: DLL4 binding proteins are described herein, including antibodies, CDR-grafted antibodies, humanized antibodies, and DLL4 binding fragments thereof, proteins that bind DLL4 with high affinity, and DLL4 binding proteins that neutralize DLL4 and/or VEGF activity. The DLL4 binding proteins are useful for treating or preventing cancers and tumors and especially for treating or preventing tumor angiogenesis.

Abstract: Disclosed herein are multivalent and multispecific binding proteins, methods of making the binding proteins, and their uses in the diagnosis, monitoring, inhibition, prevention and/or treatment of cancers, tumors, and/or other angiogenesis-dependent diseases diseases characterized by aberrant DLL4 and/or VEGF expression or activity.

Abstract: Improved DLL4 binding proteins are described, including antibodies, CDR-grafted antibodies, human antibodies, and DLL4 binding fragments thereof, proteins that bind DLL4 with high affinity, and DLL4 binding proteins that neutralize DLL4 activity. The DLL4 binding proteins are useful for treating or preventing cancers and tumors and especially for treating or preventing tumor angiogenesis, and/or other angiogenesis-dependent diseases such as ocular neovascularization, or angiogenesis-independent diseases characterized by aberrant DLL4 expression or activity such as autoimmune disorders including multiple sclerosis.