Patents by Inventor Yingjuan June Lu

Yingjuan June Lu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SEQUENCING METHOD FOR CAR T CELL THERAPY
    Publication number: 20250230216
    Abstract: The present disclosure relates to methods of treating a patient with a cancer by administering to the patient a composition comprising CAR T cells and administering to the patient a small molecule linked to a targeting moiety by a linker. The disclosure also relates to compositions for use in such methods.
    Type: Application
    Filed: November 27, 2024
    Publication date: July 17, 2025
    Inventors: Richard Messmann, Christopher Paul Leamon, Haiyan Chu, Yingjuan June Lu, Philip Stewart Low, Michael C. Jensen, James Matthaei, Navin Robert Charles Pinto, Julie Ruggieri Park
  • Methods of use for CAR T cells
    Patent number: 12269862
    Abstract: The present disclosure relates to methods of treating a patient with a cancer by administering to the patient a composition comprising CAR T cells wherein the CAR T cells comprise a CAR and the CAR comprises an E2 anti-fluorescein antibody fragment, and administering to the patient a small molecule linked to a targeting moiety by a linker. The disclosure also relates to compositions for use in such methods.
    Type: Grant
    Filed: August 31, 2023
    Date of Patent: April 8, 2025
    Assignees: Endocyte, Inc., Purdue Research Foundation, Seattle Children's Hospital
    Inventors: Philip Stewart Low, Haiyan Chu, Yingjuan June Lu, Christopher Paul Leamon, Leroy W. Wheeler, II, Michael C. Jensen, James Matthaei
  • Sequencing method for CAR T cell therapy
    Patent number: 12240870
    Abstract: The present disclosure relates to methods of treating a patient with a cancer by administering to the patient a composition comprising CAR T cells and administering to the patient a small molecule linked to a targeting moiety by a linker. The disclosure also relates to compositions for use in such methods.
    Type: Grant
    Filed: February 22, 2019
    Date of Patent: March 4, 2025
    Assignees: Purdue Research Foundation, Endocyte, Inc, Seattle Children's Hospital
    Inventors: Richard Messmann, Christopher Paul Leamon, Haiyan Chu, Yingjuan June Lu, Philip Stewart Low, Michael C. Jensen, James Matthaei, Navin Robert Charles Pinto, Julie Ruggieri Park
  • METHODS OF USE FOR CAR T CELLS
    Publication number: 20240075069
    Abstract: The present disclosure relates to methods of treating a patient with a cancer by administering to the patient a composition comprising CAR T cells wherein the CAR T cells comprise a CAR and the CAR comprises an E2 anti-fluorescein antibody fragment, and administering to the patient a small molecule linked to a targeting moiety by a linker. The disclosure also relates to compositions for use in such methods.
    Type: Application
    Filed: August 31, 2023
    Publication date: March 7, 2024
    Inventors: Philip Stewart LOW, Haiyan CHU, Yingjuan June LU, Christopher Paul LEAMON, Leroy W. WHEELER, II, Michael C. JENSEN, James MATTHAEI
  • Methods of use for CAR T cells
    Patent number: 11779602
    Abstract: The present disclosure relates to methods of treating a patient with a cancer by administering to the patient a composition comprising CAR T cells wherein the CAR T cells comprise a CAR and the CAR comprises an E2 anti-fluorescein antibody fragment, and administering to the patient a small molecule linked to a targeting moiety by a linker. The disclosure also relates to compositions for use in such methods.
    Type: Grant
    Filed: January 22, 2019
    Date of Patent: October 10, 2023
    Assignees: Endocyte, Inc., Purdue Research Foundation, Seattle Children's Hospital
    Inventors: Philip Stewart Low, Haiyan Chu, Yingjuan June Lu, Christopher Paul Leamon, Leroy W. Wheeler, II, Michael C. Jensen, James Matthaei
  • SEQUENCING METHOD FOR CAR T CELL THERAPY
    Publication number: 20210346431
    Abstract: The present disclosure relates to methods of treating a patient with a cancer by administering to the patient a composition comprising CAR T cells and administering to the patient a small molecule linked to a targeting moiety by a linker. The disclosure also relates to compositions for use in such methods.
    Type: Application
    Filed: February 22, 2019
    Publication date: November 11, 2021
    Inventors: Richard MESSMANN, Christopher Paul LEAMON, Haiyan CHU, Yingjuan June LU, Philip Stewart LOW, Michael C. JENSEN, James MATTHAEI, Navin Robert Charles PINTO, Julie Ruggieri PARK
  • VITAMIN RECEPTOR DRUG DELIVERY CONJUGATES FOR TREATING INFLAMMATION
    Publication number: 20200155555
    Abstract: Described herein are compositions, methods, compounds, conjugates, and kits for use in targeted drug delivery using drug delivery conjugates containing hydrophilic spacer linkers for use in treating disease states caused by pathogenic cell populations, such as inflammatory cells.
    Type: Application
    Filed: November 13, 2019
    Publication date: May 21, 2020
    Inventors: Christopher Paul Leamon, Iontcho Radoslavov Vlahov, Yingjuan June Lu, Kevin Yu Wang, Fei You, Paul Joseph Kleindl, Hari Krishna R. Santhapuram
  • Vitamin receptor drug delivery conjugates for treating inflammation
    Patent number: 10500204
    Abstract: Described herein are compositions, methods, compounds, conjugates, and kits for use in targeted drug delivery using drug delivery conjugates containing hydrophilic spacer linkers for use in treating disease states caused by pathogenic cell populations, such as inflammatory cells.
    Type: Grant
    Filed: November 13, 2017
    Date of Patent: December 10, 2019
    Assignee: Endocyte, Inc.
    Inventors: Christopher Paul Leamon, Iontcho Radoslavov Vlahov, Yingjuan June Lu, Kevin Yu Wang, Fei You, Paul Joseph Kleindl, Hari Krishna R. Santhapuram
  • METHODS OF USE FOR CAR T CELLS
    Publication number: 20190255109
    Abstract: The present disclosure relates to methods of treating a patient with a cancer by administering to the patient a composition comprising CAR T cells wherein the CAR T cells comprise a CAR and the CAR comprises an E2 anti-fluorescein antibody fragment, and administering to the patient a small molecule linked to a targeting moiety by a linker. The disclosure also relates to compositions for use in such methods.
    Type: Application
    Filed: January 22, 2019
    Publication date: August 22, 2019
    Inventors: Philip Stewart LOW, Haiyan CHU, Yingjuan June LU, Christopher Paul LEAMON, Leroy W. WHEELER, II, Michael C. JENSEN, James MATTHAEI
  • METHOD OF TREATING CANCER BY TARGETING MYELOID-DERIVED SUPPRESSOR CELLS
    Publication number: 20190216935
    Abstract: The invention described herein relates to methods for treating a cancer using one or more compounds comprising a folate receptor binding ligand attached to a drug via a linker. More particularly, the invention described herein relates to methods for treating a cancer using one or more compounds comprising a folate receptor binding ligand attached to a drug via a linker to target myeloid-derived suppressor cells.
    Type: Application
    Filed: May 25, 2017
    Publication date: July 18, 2019
    Inventors: Philip Stewart LOW, Bingbing WANG, Christopher Paul LEAMON, Yingjuan June LU, Leroy W. WHEELER, II
  • VITAMIN RECEPTOR DRUG DELIVERY CONJUGATES FOR TREATING INFLAMMATION
    Publication number: 20180221372
    Abstract: Described herein are compositions, methods, compounds, conjugates, and kits for use in targeted drug delivery using drug delivery conjugates containing hydrophilic spacer linkers for use in treating disease states caused by pathogenic cell populations, such as inflammatory cells.
    Type: Application
    Filed: November 13, 2017
    Publication date: August 9, 2018
    Inventors: Christopher Paul Leamon, Iontcho Radoslavov Vlahov, Yingjuan June Lu, Kevin Yu Wang, Fei You, Paul Joseph Kleindl, Hari Krishna R. Santhapuram
  • Vitamin receptor drug delivery conjugates for treating inflammation
    Patent number: 9877965
    Abstract: Described herein are compositions, methods, compounds, conjugates, and kits for use in targeted drug delivery using drug delivery conjugates containing hydrophilic spacer linkers for use in treating disease states caused by pathogenic cell populations, such as inflammatory cells.
    Type: Grant
    Filed: March 27, 2015
    Date of Patent: January 30, 2018
    Assignee: Endocyte, Inc.
    Inventors: Christopher Paul Leamon, Iontcho Radoslavov Vlahov, Yingjuan June Lu, Kevin Yu Wang, Fei Yu, Paul Joseph Kleindl, Hari Krishna R. Santhapuram
  • VITAMIN RECEPTOR DRUG DELIVERY CONJUGATES FOR TREATING INFLAMMATION
    Publication number: 20170319585
    Abstract: Described herein are compositions, methods, compounds, conjugates, and kits for use in targeted drug delivery using drug delivery conjugates containing hydrophilic spacer linkers for use in treating disease states caused by pathogenic cell populations, such as inflammatory cells.
    Type: Application
    Filed: March 27, 2015
    Publication date: November 9, 2017
    Inventors: Christopher Paul Leamon, Iontcho Radoslavov Vlahov, Yingjuan June Lu, Kevin Yu Wang, Fei Yu, Paul Joseph Kleindl, Hari Krishna R. Santhapuram
  • VITAMIN RECEPTOR DRUG DELIVERY CONJUGATES FOR TREATING INFLAMMATION
    Publication number: 20150314015
    Abstract: Described herein are compositions, methods, compounds, conjugates, and kits for use in targeted drug delivery using drug delivery conjugates containing hydrophilic spacer linkers for use in treating disease states caused by pathogenic cell populations, such as inflammatory cells.
    Type: Application
    Filed: March 27, 2015
    Publication date: November 5, 2015
    Inventors: Christopher Paul Leamon, Iontcho Radoslavov Vlahov, Yingjuan June Lu
  • FOLATE CONJUGATES FOR TREATING INFLAMMATION OF THE EYE
    Publication number: 20130203680
    Abstract: The present invention relates to methods of use of folate conjugates for treating inflammatory diseases of the eye, to folate conjugates for use in treating inflammatory diseases of the eye, and to folate conjugates for use in the manufacture of a medicament for treating inflammatory diseases of the eye. More particularly, the invention is directed to the use of folate linked to one or more anti-inflammatory agents for each of the above-described uses.
    Type: Application
    Filed: September 21, 2011
    Publication date: August 8, 2013
    Applicant: ENDOCYTE, INC.
    Inventors: Christopher Paul Leamon, Iontcho Radoslavov Vlahov, Yingjuan June Lu
  • VITAMIN RECEPTOR DRUG DELIVERY CONJUGATES FOR TREATING INFLAMMATION
    Publication number: 20120258905
    Abstract: Described herein are compositions, methods, compounds, conjugates, and kits for use in targeted drug delivery using drug delivery conjugates containing hydrophilic spacer linkers for use in treating disease states caused by pathogenic cell populations, such as inflammatory cells.
    Type: Application
    Filed: December 22, 2010
    Publication date: October 11, 2012
    Applicant: ENDOCYTE, INC.
    Inventors: Christopher Paul Leamon, Iontcho Radoslavov Vlahov, Yingjuan June Lu