Patents by Inventor Yingjun Zhang

Yingjun Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AMINE COMPOUND FOR INHIBITING SSAO / VAP-1 AND USE THEREOF
    Publication number: 20200377461
    Abstract: An amine compound serving as a semicarbazide-sensitive amine oxidase (SSAO) and/or vascular adhesion protein-1 (VAP-1) inhibitor, a pharmaceutical composition, and an application thereof in medicines that can be used for treating inflammation and/or inflammation related diseases, diabetes and/or a disease related diabetes, psychiatric disorder, ischemic disease, vascular disease, fibrosis, or tissue transplant rejection.
    Type: Application
    Filed: December 28, 2018
    Publication date: December 3, 2020
    Applicant: SUNSHINE LAKE PHARMA CO., LTD.
    Inventors: Zheng GU, Jianhao LI, Zheng LI, Weihua WANG, Haoxiong QIN, Xuli WANG, Jianyu LIU, Yingjun ZHANG
  • Method for preparing pyrimidone compound
    Patent number: 10851068
    Abstract: A method for preparing a pyrimidone compound and an important intermediate in which raw materials of the preparation method are cheap, the reaction condition of preparation method is mild, the preparation method is simple to operate, and is safe and controllable, has high total yield, and thus is suitable for industrial production.
    Type: Grant
    Filed: July 3, 2018
    Date of Patent: December 1, 2020
    Assignee: SUNSHINE LAKE PHARMA CO., LTD.
    Inventors: Runfeng Lin, Xiaojun Wang, Jihua Lin, Liang Chen, Yingjun Zhang, Jiancun Zhang
  • INHIBITORS OF INFLUENZA VIRUS REPLICATION AND USES THEREOF
    Publication number: 20200339564
    Abstract: Provided herein is inhibitors of influenza virus replication and uses thereof. Specifically, provided herein a novel class of compounds as inhibitors of influenza virus replication, preparation methods thereof, pharmaceutical compositions containing these compounds, and uses of these compounds and pharmaceutical compositions thereof in the treatment of influenza.
    Type: Application
    Filed: January 4, 2018
    Publication date: October 29, 2020
    Applicant: SUNSHINE LAKE PHARMA CO., LTD.
    Inventors: Qingyun REN, Changhua TANG, Junjun YIN, Kai YI, Yibo LEI, Yejun WANG, Yingjun ZHANG
  • INHIBITORS OF INFLUENZA VIRUS REPLICATION, APPLICATION METHODS AND USES THEREOF
    Publication number: 20200299294
    Abstract: The invention provides a novel class of compounds as inhibitors of influenza virus replication, preparation methods thereof, pharmaceutical compositions containing these compounds, and uses of these compounds and pharmaceutical compositions thereof in the treatment of influenza.
    Type: Application
    Filed: June 9, 2020
    Publication date: September 24, 2020
    Applicant: SUNSHINE LAKE PHARMA CO., LTD.
    Inventors: Yingjun ZHANG, Qingyun REN, Changhua TANG, Xiaohong LIN, Junjun YIN, Kai YI
  • INFLUENZA VIRUS REPLICATION INHIBITOR AND USE THEREOF
    Publication number: 20200283454
    Abstract: Disclosed are a compound as shown in formula (I) as an influenza virus replication inhibitor and a preparation method therefor, a pharmaceutical composition comprising the compound and the use of the compound and pharmaceutical composition thereof in the treatment of influenza.
    Type: Application
    Filed: September 18, 2018
    Publication date: September 10, 2020
    Applicants: SUNSHINE LAKE PHARMA CO., LTD., NORTH & SOUTH BROTHER PHARMACY INVESTMENT COMPANY LIMITED
    Inventors: Changhua TANG, Qingyun REN, Huichao LUO, Junjun YIN, Kai YI, Yibo LEI, Yejun WANG, Yingjun ZHANG
  • DIHYDROPYRIMIDINE COMPOUNDS AND USES THEREOF IN MEDICINE
    Publication number: 20200283445
    Abstract: A dihydropyrimidine compound and use as a medicament, especially application as a medicament used for treating and preventing hepatitis B, specifically, is a compound having Formula (I) or (Ia), or a stereisomer, a tautomer, an N-oxide, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof, wherein the variables of the formulas are as defined in the specification; and also includes the use of the compound having Formula (I) or (Ia), or an enantiomer, a diastereoisomer, a tautomer, a hydrate, a solvate, or a pharmaceutically acceptable salt thereof as a medicament, especially use as a medicament for treating and preventing hepatitis B.
    Type: Application
    Filed: October 17, 2018
    Publication date: September 10, 2020
    Applicant: SUNSHINE LAKE PHARMA CO., LTD.
    Inventors: Xinchang LIU, Qingyun REN, Guanghua YAN, Siegfried GOLDMANN, Yingjun ZHANG
  • SUBSTITUTED PYRIMIDINE PIPERAZINE COMPOUND AND USE THEREOF
    Publication number: 20200276196
    Abstract: A substituted pyrimidine piperazine compound and uses thereof, and a pharmaceutical composition containing the compound and uses thereof. Wherein the compound has Formula (I), or a stereoisomer, a geometric isomer, a tautomer, an N-oxide, a hydrate, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof. The substituted pyrimidine piperazine compound and the pharmaceutical composition containing the compound can be used to inhibit 5-hydroxytryptamine reuptake and/or activate the 5-HT1A receptors. Also, a method of preparing such compounds and pharmaceutical compositions, and uses thereof in the treatment of central nervous system dysfunction.
    Type: Application
    Filed: September 21, 2018
    Publication date: September 3, 2020
    Applicants: SUNSHINE LAKE PHARMA CO., LTD., NORTH & SOUTH BROTHER PHARMACY INVESTMENT COMPANY LIMITED
    Inventors: Chuanfei JIN, Wenhe ZHONG, Haiping LIANG, Yingjun ZHANG
  • Thienopyrimidine derivative and use thereof in medicine
    Patent number: 10759812
    Abstract: The present invention relates to a thienopyrimidine derivative and use thereof in medicine, and also to a pharmaceutical composition containing the compound. The compound or pharmaceutical composition is used for inhibiting acetyl-CoA carboxylase (ACC). The present invention also relates to a method of preparing such compound and pharmaceutical composition, as well as their use in the treatment or prevention of diseases regulated by acetyl-CoA carboxylase in mammals, especially in humans.
    Type: Grant
    Filed: January 22, 2018
    Date of Patent: September 1, 2020
    Assignee: Sunshine Lake Pharma Co., Ltd.
    Inventors: Wanjun Tang, Xinye Yang, Zheng Gu, Chenlu Li, Zongyuan Zhang, Zhifu Wan, Xiaojun Wang, Yingjun Zhang
  • Inhibitors of influenza virus replication, application methods and uses thereof
    Patent number: 10717732
    Abstract: The invention provides a novel class of compounds as inhibitors of influenza virus replication, preparation methods thereof, pharmaceutical compositions containing these compounds, and uses of these compounds and pharmaceutical compositions thereof in the treatment of influenza.
    Type: Grant
    Filed: December 8, 2016
    Date of Patent: July 21, 2020
    Assignee: SUNSHINE LAKE PHARMA CO., LTD.
    Inventors: Yingjun Zhang, Qingyun Ren, Changhua Tang, Xiaohong Lin, Junjun Yin, Kai Yi
  • METHOD FOR PREPARING PYRIMIDONE COMPOUND
    Publication number: 20200157054
    Abstract: A method for preparing a pyrimidone compound and an important intermediate in which raw materials of the preparation method are cheap, the reaction condition of preparation method is mild, the preparation method is simple to operate, and is safe and controllable, has high total yield, and thus is suitable for industrial production.
    Type: Application
    Filed: July 3, 2018
    Publication date: May 21, 2020
    Applicant: NORTH & SOUTH BROTHER PHARMACY INVESTMENT COMPANY LIMITED
    Inventors: Runfeng LIN, Xiaojun WANG, Jihua LIN, Liang CHEN, Yingjun ZHANG, Jiancun ZHANG
  • Salts of 2,6-dimethylpyrimidone derivatives and uses thereof
    Patent number: 10647682
    Abstract: Provided are salts of 2,6-dimethylpyrimidone derivatives and uses thereof. Also provided are pharmaceutical compositions containing the salts.
    Type: Grant
    Filed: July 19, 2017
    Date of Patent: May 12, 2020
    Assignee: NORTH & SOUTH BROTHER PHARMACY INVESTMENT COMPANY LIMITED
    Inventors: Runfeng Lin, Liang Chen, Xiaojun Wang, Yingjun Zhang, Jiancun Zhang
  • Inhibitors of influenza virus replication, application methods and uses thereof
    Patent number: 10647693
    Abstract: The invention provides a novel class of compounds as inhibitors of influenza virus replication, preparation methods thereof, pharmaceutical compositions containing these compounds, and uses of these compounds and pharmaceutical compositions thereof in the manufacture of medicaments for treating of influenza.
    Type: Grant
    Filed: August 29, 2017
    Date of Patent: May 12, 2020
    Assignee: NORTH & SOUTH BROTHER PHARMACY INVESTMENT COMPANY LIMITED
    Inventors: Changhua Tang, Qingyun Ren, Junjun Yin, Kai Yi, Yingjun Zhang
  • SALT OF SUBSTITUTED UREA DERIVATIVE AND USE THEREOF IN MEDICINE
    Publication number: 20200121690
    Abstract: A salt of a substituted urea derivative of formula (I) and use thereof in the pharmaceutical field. Also, a pharmaceutical composition containing the salt or a combination thereof, and use of the salt or the pharmaceutical composition in the manufacture of a medicament for treating, remitting or preventing a disorder related to tyrosine kinase activity.
    Type: Application
    Filed: July 11, 2018
    Publication date: April 23, 2020
    Applicant: NORTH & SOUTH BROTHER PHARMACY INVESTMENT COMPANY LIMITED
    Inventors: Liang CHEN, Chengxi LI, Bing LIU, Yingjun ZHANG, Changchung CHENG
  • FUSED TRICYCLIC COMPOUNDS AND USES THEREOF IN MEDICINE
    Publication number: 20200113879
    Abstract: A fused tricyclic compound and use thereof as a medicament, in particular as a medicament for the treatment and/or prevention of hepatitis B. Specifically, a compound having Formula (I) or a stereoisomer, a tautomer, an N-oxide, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof, wherein each variate is as defined in specification. The compound also includes a Formula (I) or a stereoisomer, a tautomer, an N-oxide, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof as a medicament, especially as a medicament for the treatment and/or prevention of hepatitis B.
    Type: Application
    Filed: June 2, 2018
    Publication date: April 16, 2020
    Applicants: SUNSHINE LAKE PHARMA CO., LTD., NORTH & SOUTH BROTHER PHARMACY INVESTMENT COMPANY LIMITED
    Inventors: Xinchang LIU, Qingyun REN, Jianzhou HUANG, Zhimin XIONG, Jinfeng XIONG, You LI, Yang LIU, Zhifu ZOU, Guanghua YAN, Siegfried GOLDMANN, Yingjun ZHANG
  • DIHYDROPYRIMIDINE COMPOUNDS AND USES THEREOF IN MEDICINE
    Publication number: 20200115381
    Abstract: A dihydropyrimidine compound and a pharmaceutical application thereof, especially the application used for treating and preventing HBV diseases. Specifically, a compound having Formula (I) or (Ia), or an enantiomer, a diastereoisomer, a tautomer, a hydrate, a solvate, or a pharmaceutically acceptable salt thereof, wherein the variables of the formulas are as defined in the specification. Also, use of the compound having Formula (I) or (Ia), or an enantiomer, a diastereoisomer, a tautomer, a hydrate, a solvate, or a pharmaceutically acceptable salt thereof as a medicine, especially for treating and preventing HBV diseases.
    Type: Application
    Filed: June 25, 2018
    Publication date: April 16, 2020
    Applicant: NORTH & SOUTH BROTHER PHARMACY INVESTMENT COMPANY LIMITED
    Inventors: Qingyun REN, Xinchang LIU, Jianzhou HUANG, Yingjun ZHANG, Siegfried GOLDMANN
  • INHIBITORS OF INFLUENZA VIRUS REPLICATION AND USES THEREOF
    Publication number: 20200085822
    Abstract: The invention provides a class of compounds as inhibitors of influenza virus replication, preparation methods thereof, pharmaceutical compositions containing these compounds, and uses of these compounds and pharmaceutical compositions thereof in the treatment of influenza.
    Type: Application
    Filed: December 14, 2017
    Publication date: March 19, 2020
    Applicants: SUNSHINE LAKE PHARMA CO., LTD., NORTH & SOUTH BROTHER PHARMACY INVESTMENT COMPANY LIMITED
    Inventors: Changhua TANG, Qingyun REN, Junjun YIN, Kai YI, Yibo LEI, Yejun WANG, Yingjun ZHANG
  • Nitrogen-containing tricyclic compounds and uses thereof in medicine
    Patent number: 10562910
    Abstract: A nitrogen-containing tricyclic compound which acts as modulator of FXR, or a stereoisomer, a geometric isomer, a tautomer, an N-oxide, a hydrate, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof, and the use of the compound for the treatment of disease and/or condition mediated by FXR are described. And a pharmaceutical composition containing the compound disclosed herein and a method of treatment of disease and/or condition mediated by FXR comprising administering the compound or the pharmaceutical composition thereof are also described.
    Type: Grant
    Filed: August 2, 2017
    Date of Patent: February 18, 2020
    Assignee: NORTH & SOUTH BROTHER PHARMACY INVESTMENT COMPANY LIMITED
    Inventors: Xiaojun Wang, Xinye Yang, Junwen Wu, Shaohui Xiong, Shengqiang Pan, Shengtian Cao, Yingjun Zhang
  • INHIBITORS OF INFLUENZA VIRUS REPLICATION AND USES THEREOF
    Publication number: 20200010472
    Abstract: A class of compounds as inhibitors of influenza virus replication, preparation methods thereof, pharmaceutical compositions containing these compounds, and uses of these compounds and pharmaceutical compositions thereof in the treatment of influenza.
    Type: Application
    Filed: March 1, 2018
    Publication date: January 9, 2020
    Applicant: SUNSHINE LAKE PHARMA CO., LTD.
    Inventors: Changhua TANG, Qingyun REN, Junjun YIN, Kai YI, Yibo LEI, Yejun WANG, Yingjun ZHANG
  • Inhibitors of influenza virus replication, application methods and uses thereof
    Patent number: 10501444
    Abstract: The invention provides a novel class of compounds as inhibitors of influenza virus replication, preparation methods thereof, pharmaceutical compositions containing these compounds, and uses of these compounds and pharmaceutical compositions thereof in the treatment of influenza.
    Type: Grant
    Filed: August 15, 2017
    Date of Patent: December 10, 2019
    Assignees: SUNSHINE LAKE PHARMA CO., LTD., NORTH & SOUTH BROTHER PHARMACY INVESTMENT COMPANY LIMITED
    Inventors: Qingyun Ren, Changhua Tang, Junjun Yin, Kai Yi, Yingjun Zhang
  • Cathepsin K inhibitors and application thereof
    Patent number: 10494364
    Abstract: The invention relates to capthepsin K inhibitors and uses thereof, specifically relates to a class of compounds having the formula (I) which are used for treating or preventing cathepsin dependent diseases or conditions, specifically, wherein the cathepsin is capthepsin K. The compounds and compositions thereof can be used as bone resorption inhibitors for the treatment of associated diseases.
    Type: Grant
    Filed: August 26, 2016
    Date of Patent: December 3, 2019
    Assignees: SUNSHIN LAKE PHARMA CO., LTD, NORTH & SOUTH BROTHER PHARMACY INVESTMENT COMPANY LIMITED
    Inventors: Xiaojun Wang, Pingjian Zhou, Chuanwen Yang, Changwei Huang, Shaohui Xiong, Yingjun Zhang, Jiancun Zhang