Abstract: Provided are an anti-tumor fusion protein, a preparation method therefor and an application thereof. Specifically, the fusion protein contacts a CPP element, an optional linking element, and a SH2 domain of SHP2 or SHP1 or an active fragment thereof. The obtained fusion protein has an extremely excellent anti-tumor effect.

Abstract: The present application discloses two anti-GDF15 neutralizing monoclonal antibodies and uses thereof. The variable regions of the light chain and heavy chain of the antibodies G1 and G2 with neutralizing activity are provided. Anti-GDF15 mouse monoclonal antibodies were prepared by the hybridoma technology, anti-GDF15 hybridoma cell lines capable of stable secretion with high specificity were screened out, ascites were prepared to obtain high-specificity and high-affinity anti-GDF15 monoclonal antibodies and two anti-GDF15 monoclonal antibodies with neutralizing activity were identified for the first time by constructing an antibody neutralization detection system.

Abstract: The present application provides a driving circuit of power devices, a switching circuit and a power conversion circuit. The driving circuit is configured to control switching actions of N power devices connected in parallel, where N?2 and N is a positive integer; the driving circuit includes a driving input circuit and a common magnetic bead, where a first end of the driving input circuit is electrically connected to N first ends of the common magnetic bead, N second ends of the common magnetic bead are electrically connected to control ends of the N power devices in a one-to-one correspondence, and a second end of the driving input circuit is electrically connected to second ends of the N power devices.

Abstract: The present invention discloses a dual-polarized wide-stopband filtering antenna and a communications device, the antenna comprising a dielectric substrate, a metal ground plate, a metal radiating patch, metal feeding arms, a metal square ring stub, metal transverse stubs, and metal probes, wherein the dielectric substrate is a rectangular cavity structure, the metal ground plate is disposed on the bottom surface of the dielectric substrate, and the metal radiating patch is disposed in the middle of the top surface of the dielectric substrate; the metal transverse stubs and the metal square ring stub are located inside the rectangular cavity and are connected on the same layer; the metal feeding arms are located between the metal square ring stub and the metal radiating patch; one end of the metal probe and a circular hole disposed on the metal ground plate form a coaxial feeding structure, and the other end of the metal probe is linked with the midpoint of the metal transverse stub and it is simultaneously c

Abstract: The present invention discloses a dual-polarized wide-stopband filtering antenna and a communications device, the antenna comprising a dielectric substrate, a metal ground plate, a metal radiating patch, metal feeding arms, a metal square ring stub, metal transverse stubs, and metal probes, wherein the dielectric substrate is a rectangular cavity structure, the metal ground plate is disposed on the bottom surface of the dielectric substrate, and the metal radiating patch is disposed in the middle of the top surface of the dielectric substrate; the metal transverse stubs and the metal square ring stub are located inside the rectangular cavity and are connected on the same layer; the metal feeding arms are located between the metal square ring stub and the metal radiating patch; one end of the metal probe and a circular hole disposed on the metal ground plate form a coaxial feeding structure, and the other end of the metal probe is linked with the midpoint of the metal transverse stub and it is simultaneously c

Abstract: It is a system for supplying power to at least one load. The system comprises at least one power source, load bank and control device coupled to the at least one load. The load bank is coupled to at least one power source and at least one load. The load bank comprises a controllable voltage source, at least three resistors coupled between an output side of the controllable voltage source and the at least one power source, and at least one storage element. The controllable voltage source comprises more than one switches. And the at least one storage element comprises one or more capacitors, batteries, or combinations thereof. The control device is configured for controlling the switches during a first condition such that, to the extent that an output power of the at least one power source exceeds a requisite power of the at least one load, any excess output power is either supplied to the at least one storage element or consumed by the at least three resistors.

Abstract: A method for controlling a plurality of series connected switch modules each including at least two parallel connected electronic switches, the method includes the step of, in response to failure of any electronic switch of one or more switch modules, turning on any non-faulty electronic switch of one or more faulty switch modules when the electronic switches of other non-faculty switch modules are controlled to be turned on.

Abstract: An electric coupler includes a body, a first electrical path through the body having a first resistance to electric current within a first frequency range and a second electrical path through the body having a second resistance to electric current within a second frequency range.

Abstract: The present disclosure relates to a snubber circuit which comprises a static snubber unit, connected in parallel with the switch, for balancing a static voltage sharing across a switch when the switch is in a state of turn-on or turn-off; and a dynamic snubber unit for balance a dynamic voltage sharing across the switch when the switch is in a process of turn-on or turn-off, comprising a dynamic voltage sharing capacitor connected in parallel with the switch and having a relationship between a capacitance and a voltage of the dynamic voltage sharing capacitor; and a controller for controlling the capacitance of the dynamic voltage sharing capacitor to be in a predetermined working area of capacitance rising while the voltage across the switch is increasing. The present disclosure also relates to a power semiconductor device.

Abstract: A protection circuit for a controllable switch comprising a control terminal, a first terminal, and a second terminal having a lower electric potential than the first terminal, the protection device comprising: an active clamping module, coupled between the first terminal and the control terminal of the controllable switch, configured to clamp a first voltage across the first terminal and the second terminal; and a damping module, coupled to an output of the active clamping module and configured to damp oscillations of a second voltage across the control terminal and the second terminal. Embodiments of the present disclosure also relate to a protection method for a controllable switch.

Abstract: A direct current (DC) circuit breaker for power transmission or distribution system includes a current sensor for sensing current of a system, a controller, a physical switch, and multiple switch modules. The multiple switch modules are electrically coupled to the current sensor and the physical switch in series. Each switch module includes multiple base elements electrically coupled in parallel. Each base element includes a first silicon carbide (SiC) metal-oxide-semiconductor field-effect transistor (MOSFET) and a second SiC MOSFET electrically coupled in an opposite series connection mode. The first and second SiC MOSFETs are configured in a synchronous rectification mode by channel reverse conduction control. The controller controls the multiple switch modules to connect current in the system, and break current of the multiple switch modules according to sensed current signals from the current sensor.

Abstract: A method for controlling a plurality of series connected switch modules each including at least two parallel connected electronic switches, the method includes the step of, in response to failure of any electronic switch of one or more switch modules, turning on any non-faulty electronic switch of one or more faulty switch modules when the electronic switches of other non-faculty switch modules are controlled to be turned on.

Abstract: The present disclosure relates to a snubber circuit which comprises a static snubber unit, connected in parallel with the switch, for balancing a static voltage sharing across a switch when the switch is in a state of turn-on or turn-off; and a dynamic snubber unit for balance a dynamic voltage sharing across the switch when the switch is in a process of turn-on or turn-off, comprising a dynamic voltage sharing capacitor connected in parallel with the switch and having a relationship between a capacitance and a voltage of the dynamic voltage sharing capacitor; and a controller for controlling the capacitance of the dynamic voltage sharing capacitor to be in a predetermined working area of capacitance rising while the voltage across the switch is increasing. The present disclosure also relates to a power semiconductor device.

Abstract: A method used to control the operation of a converting device such that it can provide multi-level output voltage for loads. This method comprises at least the steps of: determine whether the load which the converter is providing electricity for is operating under the first condition or the second condition; generate the first pulse signal after determining that this load is operating under the first condition, select at least one of at least three different current paths, such that when the converter is selecting any of the current paths, it can provide output voltage at the same level; as well as generate the second pulse signal after determining that this load is operating under the second condition, such that the converter can perform the regular energy conversion operations.

Abstract: It is a system for supplying power to at least one load. The system comprises at least one power source, load bank and control device coupled to the at least one load. The load bank is coupled to at least one power source and at least one load. The load bank comprises a controllable voltage source, at least three resistors coupled between an output side of the controllable voltage source and the at least one power source, and at least one storage element. The controllable voltage source comprises more than one switches. And the at least one storage element comprises one or more capacitors, batteries, or combinations thereof. The control device is configured for controlling the switches during a first condition such that, to the extent that an output power of the at least one power source exceeds a requisite power of the at least one load, any excess output power is either supplied to the at least one storage element or consumed by the at least three resistors.

Abstract: A circuit includes a switching module, a control module, and a driving module. The driving module is electrically coupled between the control module and the switching module for generating a driving signal. The driving module includes a normal driving unit and a fault protection unit. The normal driving unit is for turning on and off the switching module according to a first command signal from the control module. The fault protection unit is for lowering the driving signal from a driving value to a protection value according to a second command signal from the control module during a fault protection period after the control module receives a fault signal.

Abstract: A circuit includes first and second electronic switches, first and second excitation circuits, and first and second inductors. The first and second electronic switches are electrically coupled in series. The first and second excitation circuits are used for respectively controlling the first and second electronic switches to be turned on and turned off and are configured to synchronously switch the first and second electronic switches. The first inductor is electrically coupled between the first excitation circuit and the first electronic switch, for transmitting the switch control signal of the first excitation circuit to the first electronic switch. The second inductor is electrically coupled between the second excitation circuit and the second electronic switch, for transmitting the switch control signal of the second excitation circuit to the second electronic switch.

Abstract: A system having an alternating current (AC) driven LED unit, an AC voltage regulator, and a controller is provided. The AC driven LED unit includes a first LED and a second LED coupled in reverse parallel. The AC voltage regulator is operable to receive AC voltage originating from an AC voltage source, regulate the AC voltage according to control signals from the controller, and apply regulated AC voltage to the AC driven LED unit, so as to enable the first LED and the second LED to emit light according to the regulated AC voltage. In addition, a method is provided for driving the LED by regulating the AC voltage. By regulating the AC voltage using the AC voltage regulator, benefits of restraining voltage fluctuations, reducing THD, improving power factor, providing dimming control, and mitigating flicker phenomenon can be achieved.

Abstract: A semiconductor module comprising a plurality of electrically conductive top plates, an electrically conductive base plate, a plurality of semiconductor chips installed on the base plate, a first power supply connected to the plates, a second power supply connected to the plates and an electrically insulating outer casing component. The semiconductor chips are individually in contact with the top plates. Each semiconductor chip comprises a first electrode electrically coupled with the base plate, and a second electrical pole electrically coupled with the corresponding top plate. The first power supply connecting plate is equipped with protruding parts that are individually in electrical contact with the top plates. The second power supply connecting plate is electrically connected to the base plate. The outer casing component is used to integrate the first power supply connecting plate and the second power supply connecting plate. The outer casing component comprises at least one opening.

Abstract: An electric coupler includes a body, a first electrical path through the body having a first resistance to electric current within a first frequency range and a second electrical path through the body having a second resistance to electric current within a second frequency range.