Patents by Inventor Yingrui Dai

Yingrui Dai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Processes of preparing a JAK1 inhibitor
    Patent number: 11685731
    Abstract: The present application provides processes for preparing 4-[3-(cyanomethyl)-3-(3?,5?-dimethyl-1H, 1?H-4,4?-bipyrazol-1-yl)azetidin-1-yl]-2,5-difluoro-N-[(1S)-2,2,2-trifluoro-1-methylethyl]benzamide, and phosphoric acid salt thereof, which is useful as a selective (Janus kinase 1) JAK1 inhibitor, as well as salt forms and intermediates related thereto.
    Type: Grant
    Filed: June 2, 2021
    Date of Patent: June 27, 2023
    Assignee: Incyte Corporation
    Inventors: Jiacheng Zhou, Yingrui Dai, Zhongjiang Jia, Yongchun Pan, James M. Parks, Anthony J. Tomaine, Jianji Wang, Aibin Zhang
  • PROCESSES OF PREPARING A JAK1 INHIBITOR
    Publication number: 20210380563
    Abstract: The present application provides processes for preparing 4-[3-(cyanomethyl)-3-(3?,5?-dimethyl-1H, 1?H-4,4?-bipyrazol-1-yl)azetidin-1-yl]-2,5-difluoro-N-[(1S)-2,2,2-trifluoro-1-methylethyl]benzamide, and phosphoric acid salt thereof, which is useful as a selective (Janus kinase 1) JAK1 inhibitor, as well as salt forms and intermediates related thereto.
    Type: Application
    Filed: June 2, 2021
    Publication date: December 9, 2021
    Inventors: Jiacheng Zhou, Yingrui Dai, Zhongjiang Jia, Yongchun Pan, James M. Parks, Anthony J. Tomaine, Jianji Wang, Aibin Zhang
  • PROCESSES OF PREPARING A JAK1 INHIBITOR AND NEW FORMS THERETO
    Publication number: 20180099978
    Abstract: This invention relates to processes for preparing a JAK1 inhibitor having Formula Ia: as well as new forms of the inhibitor.
    Type: Application
    Filed: September 22, 2017
    Publication date: April 12, 2018
    Inventors: Jiacheng Zhou, Pingli Liu, Shili Chen, Yongzhong Wu, Dengjin Wang, Zhongjiang Jia, Lei Qiao, William Frietze, Michael Xia, Yingrui Dai
  • Processes of preparing a JAK1 inhibitor and new forms thereto
    Patent number: 9802957
    Abstract: This invention relates to processes for preparing a JAK1 inhibitor having Formula Ia: as well as new forms of the inhibitor.
    Type: Grant
    Filed: April 29, 2015
    Date of Patent: October 31, 2017
    Assignee: Incyte Corporation
    Inventors: Jiacheng Zhou, Shili Chen, Yongzhong Wu, Zhongjiang Jia, Yingrui Dai
  • PROCESSES OF PREPARING A JAK1 INHIBITOR AND NEW FORMS THERETO
    Publication number: 20150344497
    Abstract: This invention relates to processes for preparing a JAK1 inhibitor having Formula Ia: as well as new forms of the inhibitor.
    Type: Application
    Filed: April 29, 2015
    Publication date: December 3, 2015
    Applicant: INCYTE CORPORATION
    Inventors: Jiacheng Zhou, Pingli Liu, Shili Chen, Yongzhong Wu, Dengjin Wang, Zhongjiang Jia, Lei Qiao, William Frietze, Michael Xia, Yingrui Dai