Abstract: Provided are a murine or fully human monoclonal antibody targeting SEMA4D and a preparation method therefor, wherein the antibody binds to the SEMA4D antigen and has activities such as combating tumors.

Abstract: This application discloses a data processing method. A first apparatus obtains a first feature of a first data block in storage space. The first feature includes a read/write feature related to the first data block and a read feature of a second data block adjacent to the first data block. The first apparatus inputs the first feature into an access frequency prediction model, to obtain access frequency of the first data block. The access frequency of the first data block is used to determine a type of the first data block. To be specific, in embodiments of this application, future access frequency of the first data block is predicted by using a multidimensional feature of the first data block (the read/write feature of the first data block and a read feature of an adjacent data block).

Abstract: Systems and methods for selecting one or more characteristics for a netlist. A graph data structure is generated, the components of the netlist and connections therebetween being represented by nodes and edges, respectively, in the graph data structure, wherein the edges between the nodes indicate types of the connections between the components. The graph data structure is processed to select one or more characteristics for the components.

Abstract: The application discloses a liquid crystal display panel and a display device. In the liquid crystal display panel, each pixel unit includes a first sub-pixel and a second sub-pixel. The polarities of the data voltages received by two adjacent pixel units sharing the same data line are opposite. In each pixel unit, the driving timing of the first sub-pixel is earlier than the driving timing of the second sub-pixel, and the duty cycle of the scan signal received by the first sub-pixel is greater than the duty cycle of the scan signal received by the second sub-pixel.

Abstract: Systems and methods are described herein to control brightness based on image content or other inputs to a display system. A dual-control system may integrate both slow control operations and fast control operations into a cohesive brightness management system. By using both shorter-term (e.g., fast control) and longer-term (e.g., slow control) brightness adjustment operations, the electronic device may quickly respond to high luminance and high brightness situations that may cause burn-in into the display, image artifacts, or other damage. Responding quickly to these high consumption situations may prevent damage or perceivable upset to an ongoing process, among other benefits.

Abstract: Devices and methods are provided to overdrive or underdrive a display panel to account for display pixel hysteresis due to several frames of pixel history. An electronic device may include an electronic display and processing circuitry. The electronic display includes a number of display pixels. The processing circuitry may generate image data for the display pixels. The processing circuitry may receive a current frame value of the image data targeted for a first display pixel and, based at least in part on the current frame value and a pixel history of the first display pixel—may indicate a gray level for a number of previous frames—generate a compensated value by which to drive the first pixel to overcome pixel hysteresis to reach the desired luminance at an initial response.

Abstract: The present invention discloses a method for constructing and optimizing a molecular structure model of lignite, comprising: collecting and processing a lignite sample, analyzing a lignite experimental sample, calculating the number of carbon atoms in lignite and the number of carbon atoms in other parameters, obtaining the sizes of aromatic clusters, and determining the composition features and number of aromatic structural units in lignite; calculating the total number of carbon atoms and the number of aliphatic carbon atoms in lignite; obtaining the categories and number of oxygen-containing functional groups in lignite based on the contents of aromatic hydrocarbon, aliphatic hydrocarbon and various oxygen-containing functional groups, and designing the structural forms of nitrogen and sulfur; constructing a molecular structure model of lignite.

Abstract: The present disclosure discloses IL-2 mutants and uses thereof. More specifically, the disclosure provides IL-2 mutants and corresponding fusion proteins, conjugates, nucleic acid fragments, vectors, host cells, methods for preparing the mutants or fusion proteins, IL-2 mutants or fusion proteins prepared according to the methods, pharmaceutical compositions, pharmaceutical uses, methods for treating diseases, and methods for preferentially stimulating regulatory T cells. Compared to wild-type IL-2, the IL-2 mutants of the present disclosure have higher Tm values and improved stability; alternatively, the IL-2 mutants of the present disclosure have an increased yield or changed binding activity to the IL-2R?? complexes compared to wild-type IL-2.

Abstract: Disclosed herein are chimeric blastocysts, such as chimeric blastocysts derived from a host blastocyst from a first mammalian species and having donor pluripotent stem cells from a second mammalian species, wherein the donor pluripotent stem cells have reduced expression or reduced biological activity of one or more proteins in the TLR/NF-kB signaling pathway or the p53 pathway. Methods of preparing chimeric blastocysts and methods of obtaining mammalian organs and tissues are also provided.

Abstract: Provided are a murine or fully human monoclonal antibody targeting SEMA4D and a preparation method therefor, wherein the antibody binds to the SEMA4D antigen and has activities such as combating tumors.

Abstract: A BLyS antibody, preparation method therefor and application thereof, the BLyS antibody comprising one or more of CDR1, CDR2 and CDR3 of a heavy chain variable region of the BLyS antibody, and/or one or more of CDR1, CDR2 and CDR3 of a light chain variable region of the BLyS antibody. An amino acid sequence of the antibody is shown in a sequence listing. The BLyS antibody has a high affinity, and may observably and effectively seal a BLyS protein at a protein level and a cell level, and prevent the BLyS protein from binding to a receptor. The BLyS antibody lacks a cross-reaction with homologous protein antigens such as human APRIL, and enjoys good biological activity. The BLyS antibody may inhibit the proliferation of human BLyS-induced mouse B cells and may therefore be used for preparing a drug for preventing or treating diseases associated with BLyS expression or dysfunction.