Abstract: A digital microfluidic apparatus and a driving method therefor. The digital microfluidic apparatus comprises a digital microfluidic chip (10), a thermal control apparatus (20), and an elastic support apparatus (30). The digital microfluidic chip (10) is provided with a droplet channel (91), and the droplet channel (91) is configured to allow droplets (90) to move therein; the thermal control apparatus (20) is disposed on one side of the digital microfluidic chip (10), and is configured to generate at least two independent and non-interference hot zones in the droplet channel (91), and control the temperature of each hot zone; and the elastic support apparatus (30) is disposed on the side of the thermal control apparatus (20) away from the digital microfluidic chip (10), and is configured to drive the thermal control apparatus (20) to be pasted on the surface of the digital microfluidic chip (10).

Abstract: Provided are a class of compounds, represented by formula (I??), as selective EGFR inhibitors, a pharmaceutical composition containing the compounds, useful intermediates for preparing the compounds, and a method for using the compounds of the present invention to treat cell proliferative diseases, such as cancers.

Abstract: A bispecific antibody directed against Claudin 18.2 and CD3, pharmaceutical compositions including the bispecific antibody, and a use thereof in the treatment of cancer are provided. The bispecific antibody includes an anti-CLDN18.2 binding domain and an anti-CD3 binding domain, the first binding domain being capable of binding to a CLDN18.2 protein, the second binding domain being capable of binding to CD3.

Abstract: The present invention provides a novel aminopyrimidine compound as a fourth-generation EGFR (T790M/C797S mutation) selective inhibitor, a pharmaceutical composition comprising the compound, an intermediate useful for preparing the compound, and a method for treating a cell proliferative disease, such as a cancer, by using the compound of the present invention.

Abstract: A method includes detecting a signal on a switching node connected to a power switch, detecting a gate drive voltage of the power switch, during a gate drive process of the power switch, reducing a gate drive current based on a first comparison result obtained from comparing the signal with a first threshold, and during the gate drive process of the power switch, increasing the gate drive current based on a second comparison result obtained from comparing the gate drive voltage with a second threshold.

Abstract: A method includes applying an excitation including a voltage step to a resonant tank comprising a first coil and a capacitor, comparing a damped sinusoidal waveform having a resonant attenuation envelope with a predetermined threshold voltage and detecting a last time instant at which a value of the damped sinusoidal waveform is equal to the predetermined threshold voltage, calculating a quality factor of the resonant tank based on a plurality of parameters derived from the last time instant, and determining whether a foreign object is magnetically coupled to the first coil based on the quality factor.

Abstract: Provided are a class of compounds, represented by formula (I??), as selective EGFR inhibitors, a pharmaceutical composition containing the compounds, useful intermediates for preparing the compounds, and a method for using the compounds of the present invention to treat cell proliferative diseases, such as cancers.

Abstract: A method includes detecting a signal on a switching node connected to a power switch, detecting a gate drive voltage of the power switch, during a gate drive process of the power switch, reducing a gate drive current based on a first comparison result obtained from comparing the signal with a first threshold, and during the gate drive process of the power switch, increasing the gate drive current based on a second comparison result obtained from comparing the gate drive voltage with a second threshold.

Abstract: Provided are an anti-CLDN18.2 antibody or an antigen-binding fragment thereof, a derivative comprising said antibody or antigen-binding fragment thereof, a pharmaceutical composition, and related use of said antibody or antigen-binding fragment thereof for treating, diagnosing and detecting cancers.

Abstract: A method includes applying an excitation including a voltage step to a resonant tank comprising a first coil and a capacitor, comparing a damped sinusoidal waveform having a resonant attenuation envelope with a predetermined threshold voltage and detecting a last time instant at which a value of the damped sinusoidal waveform is equal to the predetermined threshold voltage, calculating a quality factor of the resonant tank based on a plurality of parameters derived from the last time instant, and determining whether a foreign object is magnetically coupled to the first coil based on the quality factor.

Abstract: Disclosed is a spirocyclic aryl phosphorus oxide or sulfide as an ALK inhibitor, particularly, a compound represented by formula (I) as an ALK inhibitor or pharmaceutically acceptable salt thereof.

Abstract: Disclosed is a spirocyclic aryl phosphorus oxide or sulfide as an ALK inhibitor, particularly, a compound represented by formula (I) as an ALK inhibitor or pharmaceutically acceptable salt thereof.

Abstract: A displaying method of displaying a downloading progress of a file, including the following steps: downloading and restoring a poster of the file, and processing the poster to allow the poster to display the downloading progress of the other content of the file. With the present disclosure, the downloading progress of the other content of the file is displayed in the poster, and users are able to obtain the downloading progress when watching the poster, which brings a good using experience of products applying the displaying method.

Abstract: A method for customizing an interface in a TV set is provided in the present disclosure. This method comprises the following steps of: step a: setting a TV playing region and a customized function region; step b: storing the customized interface setting parameters into a memory of the TV set; and step c: invoking and displaying the customized interface from the memory depending on the user's settings when the TV set is powered on. By disposing a customized function region, the method for customizing an interface in a TV set according to the present disclosure allows the user who is watching the TV to also acquire other useful information depending on his own needs, and can also satisfy tastes of different users. This enriches functions of the TV set and makes it possible for the user to acquire interested information quickly through the TV set.

Abstract: A displaying method of displaying a downloading progress of a file, including the following steps: downloading and restoring a poster of the file, and processing the poster to allow the poster to display the downloading progress of the other content of the file. With the present disclosure, the downloading progress of the other content of the file is displayed in the poster, and users are able to obtain the downloading progress when watching the poster, which brings a good using experience of products applying the displaying method.

Abstract: The present disclosure provides a playing progress indicating method for time-shifted television and a TV set, which can calculate a time value indicated by a program time-shifted progress indicia by use of a time scaling unit and provide a very intuitive time progress indicator for a user. Therefore, the playing progress indicating method for time-shifted television and the TV set of the present disclosure are intuitive and convenient to use.