Patents by Inventor Yingzhe Li

Yingzhe Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240343796
    Abstract: Provided herein are antibodies that specifically bind to GPRC5D. Also described are related polynucleotides capable of encoding the provided GPRC5D-specific antibodies or antigen-binding fragments, cells expressing the provided antibodies or antigen-binding fragments, as well as associated vectors and detectably labeled antibodies or antigen-binding fragments. In addition, methods of using the provided antibodies are described. For example, the provided antibodies may be used to diagnose, treat, or monitor GPRC5D-expressing cancer progression, regression, or stability; to determine whether or not a patient should be treated for cancer; or to determine whether or not a subject is afflicted with GPRC5D-expressing cancer and thus may be amenable to treatment with a GPRC5D-specific anti-cancer therapeutic, such as the multispecific antibodies against GPRC5D and CD3 described herein.
    Type: Application
    Filed: December 4, 2023
    Publication date: October 17, 2024
    Inventors: Ricardo Attar, Francois Gaudet, Mark Tornetta, Alexey Teplyakov, Mark Mendonca, Suzanne Edavettal, Kodandaram Pillarisetti, Nathan Majewski, Yingzhe Li, Leopoldo L. Luistro, III, Diana Chin
  • Patent number: 12077592
    Abstract: The present disclosure provides for chimeric antigen receptors (CARs) that specifically target a G-protein coupled receptor, G-protein coupled receptor family C group 5 member D (GPRC5D), and immunoresponsive cells comprising such CARs, for the treatment of cancer.
    Type: Grant
    Filed: January 15, 2020
    Date of Patent: September 3, 2024
    Assignee: Janssen Biotech, Inc.
    Inventors: Ricardo Attar, Rajkumar Ganesan, Francois Gaudet, Bradley J. Heidrich, Carmen Baca Jones, John Lee, Yingzhe Li, Sanjaya Singh, Sathya Venkataramani
  • Publication number: 20240262921
    Abstract: The present disclosure provides for chimeric antigen receptors (CARs) that specifically target a G-protein coupled receptor, G-protein coupled receptor family C group 5 member D (GPRC5D), and immunoresponsive cells comprising such CARs, for the treatment of cancer.
    Type: Application
    Filed: April 23, 2024
    Publication date: August 8, 2024
    Inventors: Ricardo ATTAR, Rajkumar Ganesan, Francois Gaudet, Bradley J. Heidrich, Carmen Baca Jones, John Lee, Yingzhe Li, Sanjaya Singh, Sathya Venkataramani
  • Publication number: 20240163682
    Abstract: A method and apparatus of a user equipment (UE) in a wireless communication system is provided. The method and apparatus comprises: receiving a synchronization signals and physical broadcast channel (SS/PBCH) block; determining whether a shared spectrum channel access is enabled; determining a first index of the SS/PBCH block as a candidate SS/PBCH block index (ISSB1) based on a number of candidate SS/PBCH blocks in a half frame; and determining a second index of the SS/PBCH block as an SS/PBCH block index (ISSB2) based on a quasi-co-location (QCL) parameter (Q) indicated by a PBCH in the SS/PBCH block, wherein the SS/PBCH block index (ISSB2) is determined as: ISSB2=ISSB1 mod Q based on a determination that the shared spectrum channel access is enabled, where mod is a modular operation; or ISSB2=ISSB1 based on the determination that the shared spectrum channel access is not enabled.
    Type: Application
    Filed: January 25, 2024
    Publication date: May 16, 2024
    Inventors: Hongbo Si, Yingzhe Li
  • Patent number: 11968708
    Abstract: A method and apparatus in a wireless communication system supporting a semi-static shared spectrum channel access is provided. The method and apparatus comprises: receiving system information carried by downlink channels; identifying a duration of idle period, a fixed frame period, a number of observation slots, and an index; determining a first phase based on a first time period between a starting instance of the idle period and an ending instance of the at least one observation slot, a second phase based on a second time period between the ending instance of the at least one observation slot and an ending instance of the idle period, and a third phase based on a third time period between the ending instance of the idle period and an ending instance of the fixed frame period; and identifying the downlink channels as an idle state in the at least one observation slot.
    Type: Grant
    Filed: October 21, 2021
    Date of Patent: April 23, 2024
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Yingzhe Li, Hongbo Si, Qiongjie Lin
  • Patent number: 11943634
    Abstract: A method and apparatus of a user equipment (UE) in a wireless communication system is provided. The method and apparatus comprises: receiving a synchronization signals and physical broadcast channel (SS/PBCH) block; determining whether a shared spectrum channel access is enabled; determining a first index of the SS/PBCH block as a candidate SS/PBCH block index (ISSB1) based on a number of candidate SS/PBCH blocks in a half frame; and determining a second index of the SS/PBCH block as an SS/PBCH block index (ISSB2) based on a quasi-co-location (QCL) parameter (Q) indicated by a PBCH in the SS/PBCH block, wherein the SS/PBCH block index (ISSB2) is determined as: ISSB2=ISSB1 mod Q based on a determination that the shared spectrum channel access is enabled, where mod is a modular operation; or ISSB2=ISSB1 based on the determination that the shared spectrum channel access is not enabled.
    Type: Grant
    Filed: February 6, 2023
    Date of Patent: March 26, 2024
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Hongbo Si, Yingzhe Li
  • Patent number: 11889482
    Abstract: A method of a UE in a wireless communication system supporting a shared spectrum channel access is provided. The UE comprises: receiving, from a BS over a first downlink channel, a SS/PBCH block; determining a transmission window in which the received SS/PBCH block is located; determining whether a CORESET for Type0-PDCCH CSS is present based on the received SS/PBCH block; determining a parameter for a QCL assumption of candidate SS/PBCH blocks within the transmission window; determining a group of QCLed candidate SS/PBCH blocks within the transmission window based on the determined parameter for the QCL assumption; determining a group of slots including the Type0-PDCCH CSS, wherein each slot of the group of slots corresponds to a candidate SS/PBCH block within the group of QCLed candidate SS/PBCH blocks; and receiving, over a second downlink channel, at least one Type0-PDCCH based on the determined groups of slots including the Type0-PDCCH CSS.
    Type: Grant
    Filed: August 27, 2021
    Date of Patent: January 30, 2024
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Hongbo Si, Yingzhe Li
  • Patent number: 11884722
    Abstract: Provided herein are antibodies that specifically bind to GPRC5D. Also described are related polynucleotides capable of encoding the provided GPRC5D-specific antibodies or antigen-binding fragments, cells expressing the provided antibodies or antigen-binding fragments, as well as associated vectors and detectably labeled antibodies or antigen-binding fragments. In addition, methods of using the provided antibodies are described. For example, the provided antibodies may be used to diagnose, treat, or monitor GPRC5D-expressing cancer progression, regression, or stability; to determine whether or not a patient should be treated for cancer; or to determine whether or not a subject is afflicted with GPRC5D-expressing cancer and thus may be amenable to treatment with a GPRC5D-specific anti-cancer therapeutic, such as the multispecific antibodies against GPRC5D and CD3 described herein.
    Type: Grant
    Filed: January 20, 2023
    Date of Patent: January 30, 2024
    Assignee: JANSSEN BIOTECH, INC.
    Inventors: Ricardo Attar, Francois Gaudet, Mark Tornetta, Alexey Teplyakov, Mark Mendonca, Suzanne Edavettal, Kodandaram Pillarisetti, Nathan Majewski, Yingzhe Li, Leopoldo L. Luistro, III, Diana Chin
  • Patent number: 11864012
    Abstract: A method and apparatus in a wireless communication system is provided. The method and apparatus comprise: receiving an SS/PBCH block; determining a subcarrier spacing of the SS/PBCH block from a set of subcarrier spacings {SCS1, SCS2}; determining a subcarrier spacing of a Type0-PDCCH CSS set in a CORESET, the subcarrier spacing of the Type0-PDCCH CSS set is the same as the subcarrier spacing of the SS/PBCH block; determining a bandwidth and a number of symbols of the CORESET based on an MIB in the SS/PBCH block; determining a frequency offset from a set of frequency offsets {O1, O2}, the frequency offset is determined as being from a smallest RB index of the CORESET to a smallest RB index of the common RB overlapping with a first RB of the SS/PBCH block; determining a frequency location of the CORESET; and receiving a Type0-PDCCH.
    Type: Grant
    Filed: June 29, 2022
    Date of Patent: January 2, 2024
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Hongbo Si, Yingzhe Li
  • Publication number: 20230413324
    Abstract: A method of a base station (BS) in a wireless communication system is provide.
    Type: Application
    Filed: August 24, 2023
    Publication date: December 21, 2023
    Inventors: Yingzhe Li, Hongbo Si
  • Patent number: 11844107
    Abstract: A UE in a wireless communication system is provided. The UE comprises at least one processor configured to identify a DTTC including at least one of a first periodicity, a duration of a first transmission window, or a first timing offset of the first transmission window, wherein the DTTC is identified for the DSCH or RLM in a serving cell, and identify a DMTC including at least one of a second periodicity, a duration of a second transmission window, or a second timing offset of the second transmission window, wherein the DMTC is identified for RRM measurement based on the DSCH. The UE further comprises a transceiver operably connected to the processor, the transceiver configured to receive, from a BS, at least one DSCH from a set of DSCH over unlicensed downlink channels based on the identified DTTC, wherein the received at least one DSCH includes a SS/PBCH block.
    Type: Grant
    Filed: July 28, 2022
    Date of Patent: December 12, 2023
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Hongbo Si, Yingzhe Li
  • Patent number: 11838899
    Abstract: A method of a UE in a wireless communication system supporting a shared spectrum channel access is provided. The UE comprises: receiving, from a BS over a first downlink channel, a SS/PBCH block; determining a transmission window in which the received SS/PBCH block is located; determining whether a CORESET for Type0-PDCCH CSS is present based on the received SS/PBCH block; determining a parameter for a QCL assumption of candidate SS/PBCH blocks within the transmission window; determining a group of QCLed candidate SS/PBCH blocks within the transmission window based on the determined parameter for the QCL assumption; determining a group of slots including the Type0-PDCCH CSS, wherein each slot of the group of slots corresponds to a candidate SS/PBCH block within the group of QCLed candidate SS/PBCH blocks; and receiving, over a second downlink channel, at least one Type0-PDCCH based on the determined groups of slots including the Type0-PDCCH CSS.
    Type: Grant
    Filed: August 27, 2021
    Date of Patent: December 5, 2023
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Hongbo Si, Yingzhe Li
  • Publication number: 20230389071
    Abstract: Methods and apparatuses of a BSs and UEs in a wireless communication system are provided. A method of operating the UE comprises: receiving, from a BS over a shared spectrum channel, a first DCI including a COT of the BS; determining a first portion of the COT for a downlink transmission from the BS and a second portion of the COT for an uplink transmission to the BS, wherein the COT includes a gap between the first and second portions of the COT; performing a channel access procedure based on a duration of the gap; receiving the downlink transmission in the first portion of the COT; and transmitting the uplink transmission in the second portion of the COT based on a sensing status of the shared spectrum channel that is sensed as an idle state during the channel access procedure in the duration of the gap.
    Type: Application
    Filed: August 10, 2023
    Publication date: November 30, 2023
    Inventors: Yingzhe Li, Hongbo Si
  • Patent number: 11812517
    Abstract: A UE in a wireless communication system supporting a shared spectrum channel access is provided. The method comprises: determining a set of DSCH transmission windows based on a window periodicity, a window duration, and a window offset; determining a first set of SS/PBCH blocks within a DSCH transmission window of the set of DSCH transmission windows, wherein the first set of SS/PBCH blocks is QCLed; determining a second set of SS/PBCH blocks across at least two DSCH transmission windows being different DSCH windows of the set of DSCH transmission windows, wherein the second set of SS/PBCH blocks is QCLed; and receiving at least one SS/PBCH block that is located in the first set of SS/PBCH blocks or the second set of SS/PBCH blocks based on QCL information of the first set of SS/PBCH blocks or the second set of SS/PBCH blocks within the DSCH transmission window.
    Type: Grant
    Filed: May 25, 2021
    Date of Patent: November 7, 2023
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Hongbo Si, Yingzhe Li
  • Publication number: 20230345256
    Abstract: A method and apparatus in a wireless communication system supporting shared spectrum channel access is provided. The method and apparatus comprises: receiving a set of downlink channels supporting the shared spectrum channel access; identifying, a window for SS/PBCH block transmission, a bitmap for SS/PBCH blocks (ssb-PositionsInBurst), and a parameter for QCL assumption Q; determining, based on the identified window for the SS/PBCH block transmission, the identified bitmap for the ssb-PositionsInBurst, and the identified parameter for the QCL assumption Q, a SS/PBCH block as one of: a first set of SS/PBCH blocks assumed to be transmitted by the BS, or a second set of SS/PBCH blocks not transmitted by the BS; determining a set of resources that is not available for at least one PDSCH as overlapped with the first set of SS/PBCH blocks; and receiving the at least one PDSCH based on resource other than the determined set of resources.
    Type: Application
    Filed: June 29, 2023
    Publication date: October 26, 2023
    Inventors: Hongbo Si, Yingzhe Li
  • Patent number: 11800371
    Abstract: A method of a user equipment (UE) in a wireless communication system supporting a shared spectrum channel access is provided. The method comprises: receiving, from a base station (BS), a set of higher layer parameters including a subcarrier spacing of a physical random access channel (PRACH) preamble, a logical root index (ilog) for the PRACH preamble, and an index (zeroCorrelationZoneConfg); determining a sequence length (LRA) for the PRACH preamble based on the subcarrier spacing of the PRACH preamble; determining a physical root index (iphy) for the PRACH preamble based on the logical root index (ilog); determining a cyclic shift (NCS) for the PRACH preamble based on the index (zeroCorrelationZoneConfg); generating the PRACH preamble based on the determined sequence length LRA, the determined physical root index iphy, and the determined cyclic shift NCS; and transmitting, to the base station (BS) over the shared spectrum channel, the PRACH preamble.
    Type: Grant
    Filed: November 30, 2021
    Date of Patent: October 24, 2023
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Yingzhe Li, Hongbo Si, Eun Sun Kim
  • Patent number: 11792850
    Abstract: A UE in a wireless communication system is provided. The UE comprises at least one processor configured to identify a DTTC including at least one of a first periodicity, a duration of a first transmission window, or a first timing offset of the first transmission window, wherein the DTTC is identified for the DSCH or RLM in a serving cell, and identify a DMTC including at least one of a second periodicity, a duration of a second transmission window, or a second timing offset of the second transmission window, wherein the DMTC is identified for RRM measurement based on the DSCH. The UE further comprises a transceiver operably connected to the processor, the transceiver configured to receive, from a BS, at least one DSCH from a set of DSCH over unlicensed downlink channels based on the identified DTTC, wherein the received at least one DSCH includes a SS/PBCH block.
    Type: Grant
    Filed: July 28, 2022
    Date of Patent: October 17, 2023
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Hongbo Si, Yingzhe Li
  • Patent number: 11785649
    Abstract: A base station (BS) in a wireless communication system is provided. The BS comprises a processor configured to determine frequency units within a frequency range for a bandwidth of an operating carrier, wherein a listen-before-talk (LBT) operation is performed over each of the frequency units; and determine, for each of the frequency units, a set of intended spatial transmit (TX) parameters and a set of spatial receiver (RX) parameters of the LBT operation; and determine a subset of the frequency units for a downlink transmission based on the LBT operation performed over each of the frequency units; and a transceiver operably connected to processor, which is configured to transmit, to a user equipment (UE), downlink channels using the bandwidth corresponding to the determined subset of the frequency units.
    Type: Grant
    Filed: January 29, 2021
    Date of Patent: October 10, 2023
    Assignee: Samsung Electronics Co. , Ltd.
    Inventors: Yingzhe Li, Hongbo Si
  • Patent number: 11737135
    Abstract: Methods and apparatuses of a BSs and UEs in a wireless communication system are provided. A method of operating the UE comprises: receiving, from a BS over a shared spectrum channel, a first DCI including a COT of the BS; determining a first portion of the COT for a downlink transmission from the BS and a second portion of the COT for an uplink transmission to the BS, wherein the COT includes a gap between the first and second portions of the COT; performing a channel access procedure based on a duration of the gap; receiving the downlink transmission in the first portion of the COT; and transmitting the uplink transmission in the second portion of the COT based on a sensing status of the shared spectrum channel that is sensed as an idle state during the channel access procedure in the duration of the gap.
    Type: Grant
    Filed: August 4, 2020
    Date of Patent: August 22, 2023
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Yingzhe Li, Hongbo Si
  • Patent number: 11729797
    Abstract: A UE in a wireless communication system is provided. The UE comprises a transceiver configured to receive SS/PBCH block over downlink channels using a set of parameters based on an operation mode. The operation mode is configured for the SS/PBCH block as a first operation mode in which the SS/PBCH block is used on a LAA Scell or a second operation mode in which the SS/PBCH block is at least used on a Pcell. The set of parameters is configured as a first set of parameters for the SS/PBCH block when the operation mode of the SS/PBCH block is configured as the first operation mode or a second set of parameters for the SS/PBCH block when the operation mode of the SS/PBCH block is configured as the second operation mode. The first and second set of parameters include different information each other.
    Type: Grant
    Filed: October 25, 2021
    Date of Patent: August 15, 2023
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Hongbo Si, Yingzhe Li