Abstract: Provided are a fused bicyclic heteroaryl amide compound as a protein aggregation inhibitor, as well as the use of such compound in the treatment or prevention of neurodegenerative diseases characterized by protein aggregation, such as Alzheimer's disease, Parkinson's disease, frontotemporal dementia, dementia with Lewy bodies, Parkinson's disease dementia, multiple system atrophy, amyotrophic lateral sclerosis, Huntington's disease, and cancer.

Abstract: This application provides a motor, a watercraft propeller, and a watercraft. The motor includes: a housing with a cavity filled with insulating liquid; a stator fixed inside the cavity, with an inner rotating cavity on its inner side; and a agitation structure, rotating inside the inner rotating cavity, at least partially immersed in the insulating liquid, and configured to agitate the insulating liquid in a centrifugal or rotational form to contact and cool the stator. The agitation structure agitate the insulating liquid to the inner peripheral surface of the stator, allowing the stator to obtain the insulating liquid from the inner peripheral surface, ensuring uniform contact and heat exchange between the stator and the insulating liquid.

Abstract: A method for optimizing a layer-stacking sequence of a composite material pressure vessel. includes determining design variables of a to-be-optimized composite material pressure vessel based on design objectives thereof, the design objectives including a liner size and a working pressure of the composite material pressure vessel, and the design variables including filament winding angles, winding layer thicknesses, and winding layer quantities; establishing a finite element model based on layer-stacking information and boundary conditions of the to-be-optimized composite material pressure vessel, the layer-stacking information being the design variables; modeling the liner of the pressure vessel by solid elements, and modeling composite material layers of the pressure vessel by continuum shell elements.

Abstract: The present disclosure provides a corrugated skew rolling preparation method of a magnesium alloy bar with a gradient structure, adopts a three-roller skew rolling mill, adding a corrugated curve to a flat roll rolling section of the three-roller skew rolling mill to form a corrugated roll, the billet used is as-cast magnesium alloy bar, and steps include: simulated rolling physical experiment; rolling parameters setting; bar homogenization annealing treatment; heating treatment of bars before rolling; three-roller skew mill rolling; cooling of the rolled parts after rolling. Thus improving the preparation efficiency and preparation quality of the magnesium alloy bar with gradient structure. And further improves the formiability of magnesium alloy bar with gradient structure.

Abstract: An extraction cleaner may include a base, an upright body pivotally coupled to the base, a supply tank removably coupled to the upright body and a recovery tank removably coupled to the upright body. The base may include a non-removable door and a removable suction nozzle. At least one fluid dispensing nozzle may be provided on the door. The door may be pivotally coupled to the base for providing access to an agitator. The cleaner may include and auto-spray configuration. The cleaner may include a support on the upright portion for the recovery tank. The cleaner may include an additive tank received in a receptacle of the supply tank. The recovery tank may include a float and/or an airflow management configuration. The cleaner may include a cleaning tool and a suction changeover valve and/or a fluid changeover valve. The cleaner may include a mixing valve for supplying fluid to a fluid changeover valve.

Abstract: A blockchain-based data storage method, comprising: a target node acquires the serial number of a newly generated first block broadcasted in a blockchain system, the target node is any one of a plurality of nodes, the first block comprises block data and a block head, and the block head comprises the serial number of the first block; the target node obtains a first token seed, the first token seed is generated according to the number of nodes of the blockchain system; the target node determines a first serial number range where the first block is located on the basis of the first token seed and the serial number of the first block; and the target node determines to store the first block or store the block head of the first block on the basis of the first serial number range and a first token value of the target node.

Abstract: The present disclosure relates to suspension systems, control methods, and vehicles. One example suspension system includes a suspension assembly, a driver, a controller, a compressor, and a gas tank. The suspension assembly has a gas spring and a height sensor. The gas tank contains gas, the gas tank is connected to the compressor through a first ventilation pipe, and the compressor is connected to the gas spring through a second ventilation pipe. A first switch valve is disposed on the first ventilation pipe, and a second switch valve is disposed on the second ventilation pipe. The driver is separately electrically connected to the controller, the compressor, the first switch valve, the second switch valve, and the height sensor. The suspension system is installed between a wheel and a vehicle body of the vehicle.

Abstract: An extraction cleaner may include a base, an upright body pivotally coupled to the base, a supply tank removably coupled to the upright body and a recovery tank removably coupled to the upright body. The base may include a non-removable door and a removable suction nozzle. At least one fluid dispensing nozzle may be provided on the door. The door may be pivotally coupled to the base for providing access to an agitator. The cleaner may include and auto-spray configuration. The cleaner may include a support on the upright portion for the recovery tank. The cleaner may include an additive tank received in a receptacle of the supply tank. The recovery tank may include a float and/or an airflow management configuration. The cleaner may include a cleaning tool and a suction changeover valve and/or a fluid changeover valve. The cleaner may include a mixing valve for supplying fluid to a fluid changeover valve.

Abstract: The present disclosure belongs to the field of livestock molecular biotechnology, and provides kits and methods for pedigree division and paternity testing of domestic pigs. The kits and methods specifically select 14 SSR loci of domestic pigs, especially Anqing six-end-white pigs, and synthesize primers for corresponding loci. Through capillary electrophoresis detection of the ear tissue DNA of 98 Anqing six-end-white pigs, the count of effective alleles, heterozygosity, polymorphism information content, and genetic distance, and exclusion probability at each locus are calculated, the pedigree division of domestic pigs, especially Anqing six-end-white pigs, and paternity testing are conducted. The cumulative exclusion probability of 14 microsatellite loci is 99%.

Abstract: An extraction cleaner may include a base, an upright body pivotally coupled to the base, a supply tank removably coupled to the upright body and a recovery tank removably coupled to the upright body. The base may include a non-removable door and a removable suction nozzle. At least one fluid dispensing nozzle may be provided on the door. The door may be pivotally coupled to the base for providing access to an agitator. The cleaner may include and auto-spray configuration. The cleaner may include a support on the upright portion for the recovery tank. The cleaner may include an additive tank received in a receptacle of the supply tank. The recovery tank may include a float and/or an airflow management configuration. The cleaner may include a cleaning tool and a suction changeover valve and/or a fluid changeover valve. The cleaner may include a mixing valve for supplying fluid to a fluid changeover valve.

Abstract: A device for manufacturing a storage container by integrally winding multiple bundles of fibers in a double-layer spiral circumferential direction. The device includes a rotary drive unit and two radial slide drive units provided at two sides of the rotary drive unit, each of the two radial slide drive units is provided with several spiral winding guide wire tubes in a circumferential array and drives the spiral winding guide wire tubes to perform a radial telescopic movement, the rotary drive unit drives the spiral winding guide wire tubes on the two radial slide drive units to perform a rotation movement, the rotary drive unit is connected to the two radial slide drive units by means of brackets, and a rack plate is connected to one side of each of the two radial slide drive units away from the rotary drive unit.

Abstract: An inflation control apparatus includes seal heads at ends of a container liner on a rack; a rotary inflation connector includes a static component and a rotating component. The rotating component is connected with the seal head; an inflation core tube is in the container liner, air holes are in the inflation core tube, and the two ends of the inflation core tube are connected with the static component of the rotary inflation connector respectively. A temperature and pressure sensor is in the container liner; an air compressor provides air for an air heater, the air heater introduces the heated air into an air inlet of the inflation core tube, an air outlet of the inflation core tube is connected with an air inlet of a flow regulating valve, and an air outlet of flow regulating valve is connected with an air inlet of the air compressor.

Abstract: The present application relates to the technical field of fiber winding control, and provides a tension control method of a multi-bundle winding equipment combined driving system, which solves the problem that the tension fluctuates greatly and cannot be output constantly in the fiber winding process.

Abstract: The present disclosure relates to a profile structure of the frame of an advertising poster. Said apparatus includes a profile assembly fixedly attached to the side of a compartment, said profile assembly includes a fixing profile fixedly attached to the compartment, said fixing profile is provided in an “I” shape in cross section, wherein a number of fastening bolts are inserted in a web segment of the fixing profile, wherein the free ends of said fastening bolts are provided towards the inside of the web segment, wherein a fastening profile is provided on the inside of the web segment of the fixing profile, wherein the free ends of the fixing bolts are threaded to the fastening profile, wherein the free end of the fastening profile located outside the fixing profile is provided with a fixing slot for engaging the side edges of the advertising cloth, wherein the outside of the web segment of the fixing profile is connected with a cover.

Abstract: A device for manufacturing a storage container by integrally winding multiple bundles of fibers in a double-layer spiral circumferential direction. The device includes a rotary drive unit and two radial slide drive units provided at two sides of the rotary drive unit, each of the two radial slide drive units is provided with several spiral winding guide wire tubes in a circumferential array and drives the spiral winding guide wire tubes to perform a radial telescopic movement, the rotary drive unit drives the spiral winding guide wire tubes on the two radial slide drive units to perform a rotation movement, the rotary drive unit is connected to the two radial slide drive units by means of brackets, and a rack plate is connected to one side of each of the two radial slide drive units away from the rotary drive unit.

Abstract: Carbon fiber winding equipment includes integrated spiral and hooping winding equipment for multi-bundle fibers. The equipment includes a spiral winding unit, a hoop winding unit, and a guide base and a supporting base for supporting the spiral winding unit and the hoop winding unit. An end face of a gear driving plate includes a continuous bulbous iris curve sliding rail, a sliding rod extends into the sliding rail and is capable of driving a yarn guide shaft tube to slide radially along with the rotation of the gear driving plate. A bevel gear is capable of driving the yarn guide shaft tube to do auto-rotation motion along with the rotation of a second transmission gear ring. A ratchet driving plate rotates to drive an electric telescopic rod to push a hoop rotation plate to rotate so as to drive a hoop winding bundling device to complete a hoop winding action.

Abstract: The present disclosure provides a single or multi-coupled fault test system and fault diagnosis method for a rotor system. With the modular design, and by setting different rotating conditions and structural forms of the flexible rotor system for simulation on operation states and fault types of the rotor system, the present disclosure can implement the simulation test of the rotor system in different fault conditions and can ensure the accuracy of the test performance in the simulation test. With the establishment of the fault determination models of the rotor system in the different fault conditions, the present disclosure can accurately predict and warn the fault of the rotor system, accurately analyze the fault type, and ensure the operational reliability of the rotor system.

Abstract: Spoken language processing method and apparatus, a device, and a storage medium, which relate to the field of artificial intelligence and, in particular, to the fields of deep learning, natural-language understanding, intelligent customer service, and the like. The specific implementation solution includes: determining a word feature of a word in spoken text information; determining a correlation feature of the word in the spoken text information; and determining an effect of the word on fluency of the spoken text information according to the word feature of the word and the correlation feature of the word.

Abstract: The disclosure includes an intelligent automatic control system for mine gas chromatographs, comprising a CPU. The system may comprise a touch screen coupled to the CPU, a computer and a relay unit electrically coupled to the CPU, and a remote transmission module and a remote mobile control terminal communicatively coupled to the CPU. A digital output terminal may be electrically coupled through the relay unit to a component selected from the group consisting of a solenoid valve, at least one heater, a chromatograph motor, a six-way injection valve, a ten-way injection valve, a chromatograph automatic injection pump, FID ignition coils, a TCD bridge solenoid valve, at least one gas generator solenoid valve, and a standard gas/sample gas conversion valve. The system may comprise at least one temperature sensor, at least one gas pressure sensor, a TCD bridge module, and at least one pressure-controlling switch electrically coupled to the CPU.

Abstract: The present invention provides a method for forming a history of natural gas accumulation by using carbon isotopes by a pyrolysis experiment. The method includes: obtaining activation energy distribution and a frequency factor of light carbon methane; carrying out carbon isotope kinetics simulation of natural gas in a study area by using a spreadsheet function of Excel to obtain activation energy, a mass fraction and a frequency factor of heavy carbon methane; establishing a burial history and a thermal history of the study area based on geological data; and combining the activation energy distribution and frequency factor of the heavy carbon methane with the burial history and thermal history of the study area, and establishing an instantaneous curve, a cumulative curve and a stage cumulative curve of natural gas under geological conditions on a geologic time scale.