Patents by Inventor Yinqi WU

Yinqi WU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Monooxygenase and use in preparation of optically pure sulfoxide
    Patent number: 11345900
    Abstract: A monooxygenase having an amino acid sequence obtained by mutation of the amino acid sequence shown in SEQ ID NO:2 is disclosed. The use of the monooxygenase of the present invention in production of chiral sulfoxide-based drugs has advantages including mild reaction conditions, environmental friendliness, high yield, high optical purity of products, less peroxide products, and the like, and therefore the monooxygenase in the present invention has a good industrial application prospect in the production of proton pump inhibitors for the treatment of gastric ulcers.
    Type: Grant
    Filed: November 26, 2019
    Date of Patent: May 31, 2022
    Assignees: JIANGSU AOSAIKANG PHARMACEUTICAL CO., LTD., EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Yan Zhang, Huilei Yu, Shimiao Ren, Peng Zhao, Jianhe Xu, Yinqi Wu, Qian Zhao
  • MONOXYGENASE AND USE IN PREPARATION OF OPTICALLY PURE SULFOXIDE
    Publication number: 20220002684
    Abstract: A monooxygenase having an amino acid sequence obtained by mutation of the amino acid sequence shown in SEQ ID NO:2 is disclosed. The use of the monooxygenase of the present invention in production of chiral sulfoxide-based drugs has advantages including mild reaction conditions, environmental friendliness, high yield, high optical purity of products, less peroxide products, and the like, and therefore the monooxygenase in the present invention has a good industrial application prospect in the production of proton pump inhibitors for the treatment of gastric ulcers.
    Type: Application
    Filed: November 26, 2019
    Publication date: January 6, 2022
    Applicants: EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY, JIANGSU AOSAIKANG PHARMACEUTICAL CO., LTD.
    Inventors: Yan ZHANG, Huilei YU, Shimiao REN, Peng ZHAO, Jianhe XU, Yinqi WU, Qian ZHAO