Patents by Inventor Yinyan Zhao
Yinyan Zhao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11872307Abstract: Described herein are oral pharmaceutical compositions suitable for chewing, sucking, or buccal dissolution comprising soft gel capsules and liquid fills, methods for making the same, and methods for treating subjects in need thereof with such capsules. In particular, oral pharmaceutical compositions comprising chewable, suckable, or dissolvable soft gel capsules with various flowable fill compositions are described.Type: GrantFiled: March 25, 2022Date of Patent: January 16, 2024Assignee: PATHEON SOFTGELS INC.Inventors: YinYan Zhao, Yunhua Hu, Mervin Williams, Jr., Tatyana Dyakonov, Saujanya Gosangari, Chue Yang, Henricus Marinus Gerardus Maria Van Duijnhoven, Martin Piest, Aqeel A. Fatmi
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Publication number: 20220211616Abstract: Described herein are oral pharmaceutical compositions suitable for chewing, sucking, or buccal dissolution comprising soft gel capsules and liquid fills, methods for making the same, and methods for treating subjects in need thereof with such capsules. In particular, oral pharmaceutical compositions comprising chewable, suckable, or dissolvable soft gel capsules with various flowable fill compositions are described.Type: ApplicationFiled: March 25, 2022Publication date: July 7, 2022Inventors: YinYan Zhao, Yunhua Hu, Mervin Williams, JR., Tatyana Dyakonov, Saujanya Gosangari, Chue Yang, Henricus Marinus, Gerardus, Maria Van Duijnhoven, Martin Piest, Aqeel A. Fatmi
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Publication number: 20200121595Abstract: Described herein are oral pharmaceutical compositions suitable for chewing, sucking, or buccal dissolution comprising soft gel capsules and liquid fills, methods for making the same, and methods for treating subjects in need thereof with such capsules. In particular, oral pharmaceutical compositions comprising chewable, suckable, or dissolvable soft gel capsules with various flowable fill compositions are described.Type: ApplicationFiled: December 20, 2019Publication date: April 23, 2020Inventors: YinYan Zhao, Yunhua Hu, Mervin Williams, JR., Tatyana Dyakonov, Saujanya Gosangari, Chue Yang, Henricus Marinus, Gerardus, Maria Van Duijnhoven, Martin Piest, Aqeel A. Fatmi
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Patent number: 10555901Abstract: Described herein are oral pharmaceutical compositions suitable for chewing, sucking, or buccal dissolution comprising soft gel capsules and liquid fills, methods for making the same, and methods for treating subjects in need thereof with such capsules. In particular, oral pharmaceutical compositions comprising chewable, suckable, or dissolvable soft gel capsules with various flowable fill compositions are described.Type: GrantFiled: October 27, 2017Date of Patent: February 11, 2020Assignee: PATHEON SOFTGELS INCInventors: YinYan Zhao, Yunhua Hu, Mervin Williams, Jr., Tatyana Dyakonov, Saujanya Gosangari, Chue Yang, Henricus Marinus Gerardus Maria Van Duijnhoven, Martin Piest, Aqeel A Fatmi
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Patent number: 10195211Abstract: Described herein are topical, non-systemic, slow releasing oral pharmaceutical compositions, methods for making the same, and methods for treating subjects in need thereof with such compositions. In particular, the oral composition provides topical, non-systemic administration of one or more active pharmaceutical ingredients to the oral cavity and upper gastrointestinal track, including the esophagus. In one embodiment, the pharmaceutical composition provides topical corticosteroids to the esophagus and oral cavity.Type: GrantFiled: October 27, 2017Date of Patent: February 5, 2019Assignee: Patheon Softgels, Inc.Inventors: YinYan Zhao, Justin Hughey, Jason Vaughn, Qi Fang
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Patent number: 10188662Abstract: Described herein are oral pharmaceutical compositions suitable for chewing, sucking, or buccal dissolution comprising non-systemic corticosteroid soft lozenges, methods for making the same, and methods for treating subjects in need thereof with such lozenges. In particular, the oral composition provides topical, non-systemic administration of one or more active pharmaceutical ingredients to the oral cavity and upper gastrointestinal track, including the esophagus. In one embodiment, the oral pharmaceutical compositions comprise chewable, suckable, or buccally-dissolvable soft lozenges for the treatment of esophageal lesions. The soft lozenges provide topical, non-systemic delivery of corticosteroids to the esophagus and oral cavity.Type: GrantFiled: October 27, 2017Date of Patent: January 29, 2019Assignee: Patheon Softgels, Inc.Inventors: YinYan Zhao, Justin Hughey, Jason Vaughn, Qi Fang
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Publication number: 20180078502Abstract: Described herein are topical, non-systemic, slow releasing oral pharmaceutical compositions, methods for making the same, and methods for treating subjects in need thereof with such compositions. In particular, the oral composition provides topical, non-systemic administration of one or more active pharmaceutical ingredients to the oral cavity and upper gastrointestinal track, including the esophagus. In one embodiment, the pharmaceutical composition provides topical corticosteroids to the esophagus and oral cavity.Type: ApplicationFiled: October 27, 2017Publication date: March 22, 2018Inventors: YinYan Zhao, Justin Hughey, Jason Vaughn, Qi Fang
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Publication number: 20180049979Abstract: Described herein are oral pharmaceutical compositions suitable for chewing, sucking, or buccal dissolution comprising soft gel capsules and liquid fills, methods for making the same, and methods for treating subjects in need thereof with such capsules. In particular, oral pharmaceutical compositions comprising chewable, suckable, or dissolvable soft gel capsules with various flowable fill compositions are described.Type: ApplicationFiled: October 27, 2017Publication date: February 22, 2018Inventors: YinYan Zhao, Yunhua Hu, Mervin Williams, Tatyana Dyakonov, Saujanya Gosangari, Chue Yang, Henricus Marinus, Gerardus, Maria Van Duijnhoven, Martin Piest, Aqeel A. Fatmi
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Publication number: 20180042940Abstract: Described herein are oral pharmaceutical compositions suitable for chewing, sucking, or buccal dissolution comprising non-systemic corticosteroid soft lozenges, methods for making the same, and methods for treating subjects in need thereof with such lozenges. In particular, the oral composition provides topical, non-systemic administration of one or more active pharmaceutical ingredients to the oral cavity and upper gastrointestinal track, including the esophagus. In one embodiment, the oral pharmaceutical compositions comprise chewable, suckable, or buccally-dissolvable soft lozenges for the treatment of esophageal lesions. The soft lozenges provide topical, non-systemic delivery of corticosteroids to the esophagus and oral cavity.Type: ApplicationFiled: October 27, 2017Publication date: February 15, 2018Inventors: YinYan Zhao, Justin Hughey, Jason Vaughn, Qi Fang
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Patent number: 9877971Abstract: Described herein are oral pharmaceutical compositions suitable for chewing, sucking, or buccal dissolution comprising non-systemic corticosteroid soft lozenges, methods for making the same, and methods for treating subjects in need thereof with such lozenges. In particular, the oral composition provides topical, non-systemic administration of one or more active pharmaceutical ingredients to the oral cavity and upper gastrointestinal track, including the esophagus. In one embodiment, the oral pharmaceutical compositions comprise chewable, suckable, or buccally-dissolvable soft lozenges for the treatment of esophageal lesions. The soft lozenges provide topical, non-systemic delivery of corticosteroids to the esophagus and oral cavity.Type: GrantFiled: June 14, 2016Date of Patent: January 30, 2018Assignee: Banner Life Sciences LLCInventors: Yinyan Zhao, Justin Hughey, Jason Vaughn, Qi Fang
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Patent number: 9867834Abstract: Described herein are topical, non-systemic, slow releasing oral pharmaceutical compositions, methods for making the same, and methods for treating subjects in need thereof with such compositions. In particular, the oral composition provides topical, non-systemic administration of one or more active pharmaceutical ingredients to the oral cavity and upper gastrointestinal track, including the esophagus. In one embodiment, the pharmaceutical composition provides topical corticosteroids to the esophagus and oral cavity.Type: GrantFiled: October 14, 2016Date of Patent: January 16, 2018Assignee: Banner Life Sciences LLCInventors: Yinyan Zhao, Justin Hughey, Jason Vaughn, Qi Fang
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Patent number: 9867779Abstract: Described herein are oral pharmaceutical compositions suitable for chewing, sucking, or buccal dissolution comprising soft gel capsules and liquid fills, methods for making the same, and methods for treating subjects in need thereof with such capsules. In particular, oral pharmaceutical compositions comprising chewable, suckable, or dissolvable soft gel capsules with various flowable fill compositions are described.Type: GrantFiled: March 25, 2016Date of Patent: January 16, 2018Assignee: Patheon Softgels Inc.Inventors: Yinyan Zhao, Yunhua Hu, Mervin Williams, Tatyana Dyakonov, Saujanya Gosangari, Chue Yang, Henricus Marinus Gerardus Maria Van Duijnhoven, Martin Piest, Aqeel A Fatmi
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Publication number: 20170065613Abstract: Described herein are topical, non-systemic, slow releasing oral pharmaceutical compositions, methods for making the same, and methods for treating subjects in need thereof with such compositions. In particular, the oral composition provides topical, non-systemic administration of one or more active pharmaceutical ingredients to the oral cavity and upper gastrointestinal track, including the esophagus. In one embodiment, the pharmaceutical composition provides topical corticosteroids to the esophagus and oral cavity.Type: ApplicationFiled: October 14, 2016Publication date: March 9, 2017Inventors: Yinyan Zhao, Justin Hughey, Jason Vaughn, Qi Fang
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Publication number: 20160361320Abstract: Described herein are oral pharmaceutical compositions suitable for chewing, sucking, or buccal dissolution comprising non-systemic corticosteroid soft lozenges, methods for making the same, and methods for treating subjects in need thereof with such lozenges. In particular, the oral composition provides topical, non-systemic administration of one or more active pharmaceutical ingredients to the oral cavity and upper gastrointestinal track, including the esophagus. In one embodiment, the oral pharmaceutical compositions comprise chewable, suckable, or buccally-dissolvable soft lozenges for the treatment of esophageal lesions. The soft lozenges provide topical, non-systemic delivery of corticosteroids to the esophagus and oral cavity.Type: ApplicationFiled: June 14, 2016Publication date: December 15, 2016Inventors: Yinyan Zhao, Justin Hughey, Jason Vaughn, Qi Fang
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Publication number: 20160279056Abstract: Described herein are oral pharmaceutical compositions suitable for chewing, sucking, or buccal dissolution comprising soft gel capsules and liquid fills, methods for making the same, and methods for treating subjects in need thereof with such capsules. In particular, oral pharmaceutical compositions comprising chewable, suckable, or dissolvable soft gel capsules with various flowable fill compositions are described.Type: ApplicationFiled: March 25, 2016Publication date: September 29, 2016Inventors: Yinyan Zhao, Yunhua Hu, Mervin Williams, JR., Tatyana Dyakonov, Saujanya Gosangari, Chue Yang, Henricus Marinus, Gerardus, Maria Van Duijnhoven, Martin Piest, Aqeel A Fatmi
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Patent number: 8591943Abstract: The present invention provides methods for inhibiting mTOR using pyrazolo[1,5-a]pyrimidine compounds and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with mTOR using such compounds.Type: GrantFiled: April 8, 2010Date of Patent: November 26, 2013Assignee: Merck Sharp & Dohme Corp.Inventors: Yongqi Deng, Binyuan Sun, Hongbo Zeng, Matthew Richards, Gerald W. Shipps, Jr., Cliff C. Cheng, Yinyan Zhao, Andrew McRiner, Zhaoyang Meng, Yang Nan, Mehul F. Patel, Iwona E. Wrona, Panduranga Adulla Reddy, Brian M. Eklov, Shuyi Tang, Duan Liu, Amit K. Mandal, Lianyun Zhao, M. Arshad Siddiqui
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Publication number: 20120114739Abstract: The present invention provides methods for inhibiting mTOR using pyrazolo[1,5-a]pyrimidine compounds and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with mTOR using such compounds.Type: ApplicationFiled: April 8, 2010Publication date: May 10, 2012Inventors: Yongqi Deng, Binyuan Sun, Hongbo Zeng, Matthew Richards, Gerald W. Shipps, JR., Cliff C. Cheng, Yinyan Zhao, Andrew McRiner, Zhaoyang Meng, Yang Nan, Mehul F. Patel, Iwona E. Wrona, Panduranga Adulla Reddy, Brian M. Eklov, Shuyi Tang, Duan Liu, Amit K. Mandal, Lianyun Zhao, M. Asshad Siddiqui