Patents by Inventor Yiou Chen

Yiou Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Gene knockout method
    Patent number: 11624077
    Abstract: A donor construct and a gene knockout method, as well as a system and kit for the gene knockout are provided. The donor construct is a linear donor DNA or can be cleaved in a cell to produce the linear donor DNA. The gene knockout method uses a marker gene contained in the donor construct to enrich cells in which a gene is knocked out, thereby improving the efficiency of generating the gene knockout by a sequence-specific nuclease.
    Type: Grant
    Filed: August 8, 2017
    Date of Patent: April 11, 2023
    Assignees: Peking University, Edigene Biotechnology Inc.
    Inventors: Wensheng Wei, Yiou Chen, Yuexin Zhou, Hongmin Zhang, Pengfei Yuan, Yuan Liu