Patents by Inventor Yiping Gao

Yiping Gao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9963480
    Abstract: A novel nucleoside phosphoramidate compound of the formula below, or a stereoisomer, salt, hydrate, solvate or crystal thereof for the treatment of Flaviviridae family viral infection, especially hepatitis C viral infection, and having a good anti-HCV effect; a pharmaceutical composition having the compound, or a stereoisomer, salt, hydrate, solvate or crystal thereof:
    Type: Grant
    Filed: March 6, 2014
    Date of Patent: May 8, 2018
    Assignee: NANJING SANHOME PHARMACEUTICAL CO., LTD.
    Inventors: Yong Wang, Liwen Zhao, Xian Zhang, Sheng Bi, Yiping Gao, Hongyan Chen, Dezhong Wang, Yang Nan, Cang Zhang, Yuxiu Li, Di Zhang
  • Publication number: 20160135379
    Abstract: The present invention is a method of shoot apical meristem transformation for dicot plant via sufficient and micro wounding (SMW). The technical process includes: germinate the seeds in Petri dish or in the nutrient matrix which can be transplanted with the seedling; expose the shoot apical meristem by removing one cotyledon away; make sufficient and micro wounding transformation treatment in vivo to the apical meristem by stabbing and brushing for 2-3 times using the SMW brush having 100-5000 bristles which is 4-20 ?m in diameter for each one and 0.
    Type: Application
    Filed: September 14, 2012
    Publication date: May 19, 2016
    Inventors: Haibo Wang, Mengyu Lv, Fushuang Dong, Yanmin Zhang, Zhiheng Ren, Fan Yang, Guozhong Sun, Xian Xu, Xueping Shi, Huanhuan Zhang, He Zhao, Jianfang Chai, Yiping Gao, Yongwei Liu, Jinyong Zhu, Qiufen Han, Qiang Zhang, Huijie Ma, Zhanwu Wang, Junfeng Guan
  • Patent number: 9255107
    Abstract: In the field of pharmaceutical chemistry compounds of general formula I having heteroaryl alkynyl moiety or pharmaceutically acceptable salts, isomers, solvates, crystals or prodrugs thereof, and pharmaceutical compositions including these compounds, as well as uses of these compounds and compositions thereof in the manufacture of a medicament. The compounds have a strong inhibitory effect on BCR-ABL tyrosine kinase and are useful for treating diseases, such as tumors.
    Type: Grant
    Filed: November 27, 2013
    Date of Patent: February 9, 2016
    Assignee: NANJING SANHOME PHARMACEUTICAL CO., LTD.
    Inventors: Yong Wang, Liwen Zhao, Di Zhang, Feng Wu, Sheng Bi, Yiping Gao, Hongbin Chen, Hongyan Chen, Cang Zhang, Yang Nan, Yang Liu
  • Publication number: 20150361123
    Abstract: A novel nucleoside phosphoramidate compound, or a stereoisomer, salt, hydrate, solvate or crystal thereof for the treatment of Flaviviridae family viral infection, especially hepatitis C viral infection is provided. The pharmaceutical composition having the compound, or a stereoisomer, salt, hydrate, solvate or crystal thereof and a use of the compound or the composition in the treatment of Flaviviridae family viral infection, especially hepatitis C viral infection. The compound has a good anti-HCV effect.
    Type: Application
    Filed: March 6, 2014
    Publication date: December 17, 2015
    Applicant: NANJING SANHOME PHARMACEUTICAL CO., LTD
    Inventors: Yong WANG, Liwen ZHAO, Xian ZHANG, Sheng BI, Yiping GAO, Hongyan CHEN, Dezhong WANG, Yang NAN, Cang ZHANG, Yuxiu LI, Di ZHANG
  • Publication number: 20150344897
    Abstract: The present invention is a method of shoot apical meristem transformation for monocot plant via sufficient and micro wounding (SMW). The technical process includes: expose the apical meristem by removing the coleoptile away when the shoot grows to 0.2-2 cm after 1-2 days of seed germination; make sufficient and micro wounding transformation to the apical meristem by stabbing and brushing for 2-3 times using the SMW brush having 100-5000 bristles which is 4-20 ?m in diameter for each one and 0.5-3 mm in exposed length, and dipped with the Agrobacterium tumefaciens containing binary vector harboring exogenous genes; develop the treated meristems directly to normal plants after co-cultivation; promote the plants to develop big spikes and set more seeds; harvest the seeds of T0 plants separately; detect and identify the transformation results in T1 generation which is bred from each individual T0 plant.
    Type: Application
    Filed: September 14, 2012
    Publication date: December 3, 2015
    Applicant: HEBEI ACADEMY OF AGRICULTURE AND FORESTRY SCIENCES, INSTITUTE OF GENETICS AND PHYSIOLOGY
    Inventors: Haibo Wang, Fushuang Dong, Mengyu Lv, Yanmin Zhang, Zhiheng Ren, Fan Yang, Xinchao Liang, Wenbo Zuo, Xueping Shi, Huanhuan Zhang, Yiping Gao, He Zhao, Xian Xu, Guozhong Sun, Jianfang Chai, Yongwei Liu, Jinyong Zhu, Qiufen Han, Qiang Zhang, Huijie Ma, Zhanwu Wang, Junfeng Guan
  • Publication number: 20150299202
    Abstract: In the field of pharmaceutical chemistry compounds of general formula I having heteroaryl alkynyl moiety or pharmaceutically acceptable salts, isomers, solvates, crystals or prodrugs thereof, and pharmaceutical compositions including these compounds, as well as uses of these compounds and compositions thereof in the manufacture of a medicament. The compounds have a strong inhibitory effect on BCR-ABL tyrosine kinase and are useful for treating diseases, such as tumors.
    Type: Application
    Filed: November 27, 2013
    Publication date: October 22, 2015
    Applicant: NANJING SANHOME PHARMACEUTICAL CO., LTD.
    Inventors: Yong WANG, Liwen ZHAO, Di ZHANG, Feng WU, Sheng BI, Yiping GAO, Hongbin CHEN, Hongyan CHEN, Cang ZHANG, Yang NAN, Yang LIU
  • Publication number: 20150152088
    Abstract: The present invention belongs to the field of pharmaceutical chemistry, and specifically relates to compounds having an alkynyl heteroaromatic ring structure and pharmaceutically acceptable salts, stereoisomers, N-oxides, solvates, or prodrugs thereof, and pharmaceutical compositions comprising these compounds, as well as uses of these compounds and compositions in the manufacture of a medicament. The compounds of the present invention and the pharmaceutically acceptable salts, stereoisomers, N-oxides, solvates or prodrugs thereof and the pharmaceutical compositions comprising the compounds have better anti-tumor activity.
    Type: Application
    Filed: September 12, 2013
    Publication date: June 4, 2015
    Applicant: Nanjing Sanhome Pharmaceutical Co., Ltd.
    Inventors: Yong Wang, Liwen Zhao, Wenping Zhang, Hongyan Chen, Sheng Bi, Yiping Gao, Hongbin Chen, Yang Liu, Xin Xu, Cang Zhang
  • Publication number: 20130042618
    Abstract: A power unit includes two or more power modules (1, 2, 3), each comprising an engine (11), a transfer case (12) connected to the engine (11) and a hydraulic pump set (13) connected to the transfer case (12). A controlling method for the power unit is also disclosed. Compared to the prior art of using a single super high power engine, the hydraulic mobile crane using the in power unit has advantages of low cost, high reliability, and not being subjected to the restrictions by road transportation conditions during transportation.
    Type: Application
    Filed: April 11, 2011
    Publication date: February 21, 2013
    Applicant: HUNAN ZOOMLION SPECIAL VEHICLE CO., LTD.
    Inventors: Chunxin Zhan, Quan Liu, Yiping Gao, Weifu Li, Shaojun Wang, Hong Zhou