Patents by Inventor Yiping Zhao

Yiping Zhao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10391104
    Abstract: The present invention discloses an application of an antidepressant compound in preparation of antidepressant drugs and antidepressant health-care foods, where the antidepressant compound has a structure represented by formula I. The antidepressant compound serves as the only active ingredient or one of active ingredients of antidepressant health-care foods. The antidepressant drug is a liquid preparation, a solid preparation, a spray, an aerosol, or the like. The antidepressant compound according to the present invention is applied in preparation of antidepressant drugs and antidepressant health-care foods, and has a chemical structure different from those of existing antidepressant drugs. The anti-depressant compound has significant antidepressant activities without obvious toxic and side effects, contributes to large-scale promotion and use on the market, and has broad application prospects.
    Type: Grant
    Filed: June 8, 2016
    Date of Patent: August 27, 2019
    Assignee: ZHEJIANG ACADEMY OF MEDICAL SCIENCES
    Inventors: Yiping Ye, Xiaoyu Li, Yewei Yang, Zhengrong Zhao, Fengyang Chen, Shifang Xu, Wenhai Huang
  • Publication number: 20190202914
    Abstract: Disclosed are isolated monoclonal antibodies, comprising a CD152-binding domain, wherein the antibodies bind specifically to human CD152. Methods of making and using the antibodies to treat diseases including cancers and autoimmune diseases are also provided.
    Type: Application
    Filed: December 19, 2018
    Publication date: July 4, 2019
    Inventors: Xin GAN, Yun HE, Yuqiang SHEN, Jiuqiao ZHAO, Yiping RONG
  • Publication number: 20190194185
    Abstract: The present invention relates to phenyl [a]indole[2,3-g]quinolizine compounds represented by formula (I), a preparation method therefor, a pharmaceutical composition, and applications thereof. Specific applications are applications in the preparation of drugs for treating diseases related to a proprotein convertase subtilisin Kexin-9 (PCSK9), comprising the applications in the preparation of drugs for treating hyperlipemia, hypercholesterolemia, hypertriglyceridemia, fatty liver deformation, atherosclerosis, obesity and other metabolic diseases.
    Type: Application
    Filed: March 29, 2017
    Publication date: June 27, 2019
    Applicant: Shanghai Institute of Materia Medica, Chinese Academy of Sciences
    Inventors: Hong Liu, Yiping Wang, Fei Zhao, Jing Zhao, Jiang Wang, Cong Xi, Chenglin Wu, Hao Shen, Xu Han, Hualiang Jiang, Kaixian Chen
  • Patent number: 9202606
    Abstract: The present disclosure relates to multilayered materials that are designed to roll spontaneously into micron-sized, cylindrical “jelly roll” or scroll structures. Specifically in this disclosure, at least one of the layers is comprised of a nanosheet material.
    Type: Grant
    Filed: April 12, 2013
    Date of Patent: December 1, 2015
    Assignee: University of Georgia Research Foundation, Inc.
    Inventors: Kun Yao, Manoj Manjare, Christopher Andrew Barrett, Tina Trnka Salguero, Yiping Zhao
  • Patent number: 8975205
    Abstract: Embodiments of the present disclosure include structures, photocatalytic structures, and photoelectrochemical structures, methods of making these structures, methods of making photocatalysis, methods of splitting H2O, methods of splitting CO2, and the like.
    Type: Grant
    Filed: November 10, 2009
    Date of Patent: March 10, 2015
    Assignee: University of Georgia Research Foundation, Inc.
    Inventors: Wilson Smith, Yiping Zhao
  • Patent number: 8810789
    Abstract: The present disclosure includes methods of simultaneous analyte separation and detection using surface enhanced Raman spectroscopy (SERS)-active ultra thin layer chromatography (UTLC) chips. The SERS-active UTLC chips of the present disclosure are used to physically separate compounds within a mixture, which are then identified based on their unique SERS spectra.
    Type: Grant
    Filed: November 7, 2012
    Date of Patent: August 19, 2014
    Assignee: University of Georgia Research Foundation, Inc.
    Inventors: Yiping Zhao, Justin L. Abell, Jing Chen
  • Publication number: 20120327407
    Abstract: Embodiments of the present disclosure, in one aspect, relate to methods of analyzing SERS signals, systems for analyzing SERS signals, in particular, using an independent component analysis, and the like.
    Type: Application
    Filed: June 20, 2012
    Publication date: December 27, 2012
    Applicant: University of Georgia Research Foundation, Inc.
    Inventors: Yiping Zhao, Qun Zhao, Justin L. Abell, Joonsang Lee
  • Patent number: 8107070
    Abstract: Embodiments of the present disclosure relate to methods of melamine detection and quantification. In particular, embodiments of the present disclosure include the detection of very low concentrations of melamine using silver nanorod array substrates fabricated by oblique angle deposition (OAD) technique.
    Type: Grant
    Filed: June 11, 2010
    Date of Patent: January 31, 2012
    Assignee: University of Georgia Research Foundation, Inc.
    Inventors: Yiping Zhao, Xiaobing Du
  • Publication number: 20110245074
    Abstract: Embodiments of the present disclosure include structures, photocatalytic structures, and photoelectrochemical structures, methods of making these structures, methods of making photocatalysis, methods of splitting H2O, methods of splitting CO2, and the like
    Type: Application
    Filed: November 10, 2009
    Publication date: October 6, 2011
    Inventors: Wilson Smith, Yiping Zhao
  • Patent number: 7940387
    Abstract: Surface-enhanced Raman spectroscopic (SERS) systems and methods for detecting and differentiating biomolecules of interest, such as human immunodeficiency virus (HIV), are provided.
    Type: Grant
    Filed: June 9, 2008
    Date of Patent: May 10, 2011
    Assignee: Univeristy of Georgia Research Foundation, Inc.
    Inventors: Richard A. Dluhy, Ralph A. Tripp, Yiping Zhao, Jeremy Driskell
  • Publication number: 20110069308
    Abstract: Embodiments of the present disclosure relate to methods of melamine detection and quantification. In particular, embodiments of the present disclosure include the detection of very low concentrations of melamine using silver nanorod array substrates fabricated by oblique angle deposition (OAD) technique.
    Type: Application
    Filed: June 11, 2010
    Publication date: March 24, 2011
    Inventors: Yiping Zhao, Xiaobing Du
  • Publication number: 20110037976
    Abstract: Flexible SERS substrates, methods of making flexible SERS substrates, and methods of using flexible SERS substrates are disclosed.
    Type: Application
    Filed: August 17, 2010
    Publication date: February 17, 2011
    Inventors: Yiping Zhao, HsiaoYun Chu
  • Patent number: 7889334
    Abstract: Surface-enhanced Raman spectroscopic (SERS) systems and methods for detecting biomolecules of interest, such as a bacterium or virus are provided.
    Type: Grant
    Filed: June 16, 2008
    Date of Patent: February 15, 2011
    Assignee: University of Georgia Research Foundation, Inc.
    Inventors: Duncan C. Krause, Suzanne Marie Larkin Hennigan, Richard A. Dluhy, Jeremy Driskell, Yiping Zhao, Ralph A. Tripp
  • Patent number: 7880876
    Abstract: Surface-enhanced Raman spectroscopic (SERS) systems and methods for detecting biomolecules of interest, such as a bacterium are provided.
    Type: Grant
    Filed: July 2, 2008
    Date of Patent: February 1, 2011
    Assignee: University of Georgia Research Foundation, Inc.
    Inventors: Yiping Zhao, Richard A. Dluhy, Ralph A. Tripp, Yao-wen Huang, Hsiao Yun Chu, Yongjun Liu
  • Publication number: 20100268473
    Abstract: Embodiments of the present disclosure include a method for analysis of individual components in a multicomponent sample where the identity of the individual components is an indicator for disease.
    Type: Application
    Filed: February 19, 2009
    Publication date: October 21, 2010
    Inventors: Ralph A. Tripp, Richard A. Dluhy, Yiping Zhao, Jeremy Driskell
  • Patent number: 7738096
    Abstract: Surface-enhanced Raman spectroscopic (SERS) systems including nanostructures and capable of detecting analytes, in particular biomolecules, of interest are provided. Methods of making the SERS systems and methods for detection of a biomolecule of interest, such as a virus or other infectious agent are also provided.
    Type: Grant
    Filed: March 15, 2006
    Date of Patent: June 15, 2010
    Assignee: University of Georgia Research Foundation, Inc.
    Inventors: Yiping Zhao, Richard A. Dluhy, Ralph A. Tripp, Stephen Chaney, Saratchandra Shanmukh
  • Publication number: 20100104749
    Abstract: Substrates having nanostructures disposed thereon and methods of forming nanostructures on the substrates are disclosed.
    Type: Application
    Filed: November 20, 2009
    Publication date: April 29, 2010
    Inventors: Yiping Zhao, Jianguo Fan
  • Patent number: 7658991
    Abstract: Substrates having nanostructures disposed thereon and methods of forming nanostructures on the substrates are disclosed. In particular, embodiments of the present invention provide for structures having a substrate having a non-planar surface. In an embodiment, a portion of the non-planar surface has at least one layer of nanostructures disposed thereon.
    Type: Grant
    Filed: October 21, 2005
    Date of Patent: February 9, 2010
    Assignee: University of Georgia Research Foundation, Inc.
    Inventors: Yiping Zhao, Jianguo Fan
  • Patent number: 7656525
    Abstract: Fiber optic surface-enhanced Raman spectroscopic (SERS) systems (also referred to as “SERS system”), portable SERS systems, SERS probes, and methods of using the SERS systems and SERS probes to detect an analyte, are disclosed.
    Type: Grant
    Filed: August 6, 2007
    Date of Patent: February 2, 2010
    Assignee: University of Georgia Research Foundation, Inc.
    Inventors: Yiping Zhao, Yongjun Liu
  • Publication number: 20090303472
    Abstract: Surface-enhanced Raman spectroscopic (SERS) systems and methods for detecting biomolecules of interest, such as a bacterium are provided.
    Type: Application
    Filed: July 2, 2008
    Publication date: December 10, 2009
    Inventors: Yiping Zhao, Richard A. Dluhy, Ralph A. Tripp, Yao-wen Huang, Hsiao Yun Chu, Yongjun Liu