Patents by Inventor Yiqi Yang

Yiqi Yang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11660285
    Abstract: Disclosed in the present invention is a new triptolide derivative as shown in formula (I). Also disclosed in the present invention are a preparation method for the compound and the medical use thereof in preparation of anti-cancer drugs. Triptolide acrylate of the present invention and a pharmaceutically acceptable salt thereof have anti-cancer activity, and after animal in-vivo experiments, can effectively inhibit tumor growth in animals. A plurality of in-vitro experiments proves that same can significantly increase the protein expression quantity of p53, promote the apoptosis of tumor cells, effectively inhibit the growth of the tumor cells, and have the effect of inhibiting metastasis of cancer cells. More importantly, the toxicity of the compound to normal cells is less than that of triptolide.
    Type: Grant
    Filed: December 30, 2019
    Date of Patent: May 30, 2023
    Assignees: Guangdong Provincial Hospital of TCM, The Second Affiliated Hospital Of Guangzhou University of Chinese Medicine, The Second Clinical College Of Guangzhou University of Chinese Medicine, Guangdong Provincial Academy Of Chinese Medical Sciences
    Inventors: Bo Liu, Xianzhang Huang, Zhimin Yang, Jun Li, Quanfu Chen, Liqiao Han, Hualun Liang, Yiqi Yang, Kai Wang, Xiaowan Wang, Ennian Li, Yi Wang, Runyue Huang, Yunshan Wu, Xiaodong Han, Jinlang Zhong, Bidan Zheng
  • Publication number: 20230071444
    Abstract: This disclosure relates to processes for preparing a keratin fiber, for example, continuous process. In some embodiments, a process as described herein can comprise extruding a keratin solution into a first solution to form a first fiber; drawing the first fiber and oxidizing the first fiber to form a treated fiber; drawing the treated fiber and oxidizing the treated fiber one or more times; and setting the treated fiber to form the keratin fiber. Such processes can be useful for preparing a keratin fiber with a high draw ratio.
    Type: Application
    Filed: January 21, 2021
    Publication date: March 9, 2023
    Inventors: Yiqi Yang, Bingnan Mu, Faqrul Hassan
  • Publication number: 20230064939
    Abstract: Disclosed in the present invention is a new triptolide derivative as shown in formula (I). Also disclosed in the present invention are a preparation method for the compound and the medical use thereof in preparation of anti-cancer drugs. Triptolide acrylate of the present invention and a pharmaceutically acceptable salt thereof have anti-cancer activity, and after animal in-vivo experiments, can effectively inhibit tumor growth in animals. A plurality of in-vitro experiments proves that same can significantly increase the protein expression quantity of p53, promote the apoptosis of tumor cells, effectively inhibit the growth of the tumor cells, and have the effect of inhibiting metastasis of cancer cells. More importantly, the toxicity of the compound to normal cells is less than that of triptolide.
    Type: Application
    Filed: December 30, 2019
    Publication date: March 2, 2023
    Inventors: Bo Liu, Xianzhang Huang, Zhimin Yang, Jun Li, Quanfu Chen, Liqiao Han, Hualun Liang, Yiqi Yang, Kai Wang, Xiaowan Wang, Ennian Li, Yi Wang, Runyue Huang, Yunshan Wu, Xiaodong Han, Jinlang Zhong, Bidan Zheng
  • Publication number: 20220080628
    Abstract: A method for preparing keratin-based composites includes mixing polysaccharide nanoparticles and a keratin solution to form a nanoparticle-keratin solution; and solvent casting the nanoparticle-keratin solution to form the keratin-based composites.
    Type: Application
    Filed: September 17, 2021
    Publication date: March 17, 2022
    Inventors: Yiqi Yang, Bingnan Mu
  • Patent number: 10925913
    Abstract: The disclosure relates to a low toxic tripterygium neoglycosides, which is obtained by chemically processing tripterygium glycosides and adding triptriolide. The disclosure also discloses the application of the low toxic tripterygium neoglycosides. The tripterygium neoglycosides can effectively relieve renal pathological injury and urinary protein of nephrotic syndrome, attenuate the inflammatory level of the body, have obvious treatment effect on nephrotic syndrome, and have low toxicity and persistent effect.
    Type: Grant
    Filed: August 30, 2017
    Date of Patent: February 23, 2021
    Assignees: THE SECOND AFFILIATED HOSPITAL OF GUANGZHOU UNIVERSITY OF CHINESE MEDICINE, GUANGZHOU UNIVERSITY OF CHINESE MEDICINE
    Inventors: Bo Liu, Wei Mao, Xusheng Liu, Peng Xu, Xiaodong Han, Wen Zhou, Fangfang Xu, Yuanchao Li, Yiqi Yang, Jinbao Deng, Lilan Wu, Yunshan Wu, Weiying Chen, Ruimin Tian, Jinjian Lu, Yuqin Zhang
  • Patent number: 10828246
    Abstract: This disclosure relates to hair styling compositions and processes, and more particularly to compositions for disentangling or crosslinking hair that are useful in hair styling processes.
    Type: Grant
    Filed: October 3, 2016
    Date of Patent: November 10, 2020
    Assignee: NUtech Ventures
    Inventors: Yiqi Yang, Helan Xu, Kaili Song
  • Publication number: 20200069757
    Abstract: The disclosure relates to a low toxic tripterygium neoglycosides, which is obtained by chemically processing tripterygium glycosides and adding triptriolide. The disclosure also discloses the application of the low toxic tripterygium neoglycosides. The tripterygium neoglycosides can effectively relieve renal pathological injury and urinary protein of nephrotic syndrome, attenuate the inflammatory level of the body, have obvious treatment effect on nephrotic syndrome, and have low toxicity and persistent effect.
    Type: Application
    Filed: August 30, 2017
    Publication date: March 5, 2020
    Inventors: Bo LIU, Wei MAO, Xusheng LIU, Peng XU, Xiaodong HAN, Wen ZHOU, Fangfang XU, Yuanchao LI, Yiqi YANG, Jinbao DENG, Lilan WU, Yunshan WU, Weiying CHEN, Ruimin TIAN, Jinjian LU, Yuqin ZHANG
  • Publication number: 20170173917
    Abstract: Compression molded composites comprising at least two compressed layers of unshredded carpet and method of making compression molded composites from unshredded carpets.
    Type: Application
    Filed: December 21, 2016
    Publication date: June 22, 2017
    Inventors: Yiqi Yang, Yi Zhao, Gangwei Pan, Helan Xu
  • Publication number: 20170095409
    Abstract: This disclosure relates to hair styling compositions and processes, and more particularly to compositions for disentangling or crosslinking hair that are useful in hair styling processes.
    Type: Application
    Filed: October 3, 2016
    Publication date: April 6, 2017
    Inventors: Yiqi Yang, Helan Xu, Kaili Song
  • Publication number: 20140011416
    Abstract: A randomly-oriented 3-D fibrous structure and a method for making the same. The method involves electrospinning a spinning dope with an electrospinning apparatus, wherein the spinning dope comprises: a solvent; a polymer dissolved in the solvent, wherein the dissolved polymer is in subunits having molecular weights that are about 5 to about 150 kDa; and a surfactant; to form one or more fibers that comprise a polymer-surfactant complex and that arrange randomly and evenly in three dimensions when contacting a collecting board of the electrospinning apparatus thereby forming the randomly-oriented 3-D fibrous structure.
    Type: Application
    Filed: July 5, 2013
    Publication date: January 9, 2014
    Inventors: Yiqi Yang, Helan Xu, Shaobo Cai
  • Publication number: 20130072598
    Abstract: A thermoplastic biobased material-containing composition comprising chemically-modified feathers and/or dried distillers grains and a process for forming the thermoplastic biobased material-containing composition. More specifically, the thermoplastic biobased material-containing composition comprises one or more of the following chemically-modified biobased materials: (a) acylated biobased material having a % Acyl Content that is at least 3% and a % Weight Gain that is at least 1%, and; (b) etherified biobased material having a % Weight Gain that is at least 2%; and (c) graft polymerized biobased material having a % Monomer Conversion that is at least 40%, a % Grafting Efficiency that is at least 30%, and a % Grafting that is at least 10%.
    Type: Application
    Filed: March 19, 2012
    Publication date: March 21, 2013
    Applicant: Board of Regents of the University of Nebraska
    Inventors: Yiqi Yang, Narendra Reddy, Chunyan Hu, Jin Enqi
  • Patent number: 7887672
    Abstract: A method for extracting such natural cellulosic fiber bundles from natural cellulose sources selected from the group consisting of cornhusk, cornstalk, switchgrass leaves, switchgrass stems, rice straw, sorghum leaves, sorghum stems, soybean straw, wheat straw, cotton stems, barley straw, and combinations thereof, the method comprising performing an alkali treatment to partially delignify the cellulose source material and an enzyme treatment to depolymerize hemicellulose, break covalent links between lignin and carbohydrates, and decompose cellulose chains in the natural cellulosic source material, or a combination thereof thereby yielding extracted natural cellulosic fiber bundles having a length that is greater than that of individual cells and a fineness of at least about 1 denier and no greater than about 300 denier.
    Type: Grant
    Filed: February 16, 2007
    Date of Patent: February 15, 2011
    Assignee: University of Nebraska-Lincoln
    Inventors: Yiqi Yang, Narenda Reddy
  • Publication number: 20090069542
    Abstract: The present invention is directed to a method for processing a plant-based protein source, the method comprising an acidic extracting solution comprising a reducing agent is useful for extracting and isolating proteins from plant-based protein sources.
    Type: Application
    Filed: September 27, 2007
    Publication date: March 12, 2009
    Applicant: BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA
    Inventors: Yiqi Yang, Weijie XU, Narenda Reddy
  • Publication number: 20070199669
    Abstract: The present invention is directed to natural cellulosic fiber bundles from natural cellulose sources preferably having a length, width, strength, elongation, or other properties desirable for textiles, composites, nonwoven mats, and other applications. For example, the fiber bundles may have a length that is greater than that of individual cells and a fineness of at least about 1 denier and no greater than about 300 denier. The present invention is also directed to textiles, composites, nonwoven mats, and other applications that comprise the fiber bundles. Additionally, the present invention is directed to a method for extracting such natural cellulosic fiber bundles from a cellulose source, the method comprising performing an alkali treatment, an enzyme treatment, or both to separate the fiber bundles from connecting material in the cellulose source.
    Type: Application
    Filed: February 16, 2007
    Publication date: August 30, 2007
    Applicant: UNIVERSITY OF NEBRASKA-LINCOLN
    Inventors: Yiqi Yang, Narenda Reddy
  • Publication number: 20060282958
    Abstract: A series of new manufactured protein fibers from wheat proteins, a method and kit for production of these wheat protein fibers is provided. The method may include dissolving wheat proteins by use of at least one of an alkali, acid, alcohol, reducing agent, amino acid, chemical additive, or salt in weight ratios ranging between approximately 0.5 percent and 50 percent by weight of a single wheat protein or a combination of one or more wheat proteins. Further, the method may involve aging the dissolved wheat proteins at temperatures from approximately minus thirty degrees Celsius (?30° C.) to one hundred and fifty degrees Celsius (150° C.) for approximately one to eighty hours to obtain a spinnable solution. In addition, the method entails extruding the dissolved wheat proteins into a coagulation bath to precipitate the wheat protein fibers in which the coagulation bath includes at least one of an alkali, acid or salt.
    Type: Application
    Filed: May 25, 2006
    Publication date: December 21, 2006
    Inventors: Yiqi Yang, Narendra Reddy, Ying Li
  • Publication number: 20060180285
    Abstract: A method and kit for rice fiber extraction is provided. In an exemplary embodiment, the method may include treating rice straw with an alkali solution such as a sodium hydroxide solution. Further, the method may include extracting coarse rice fibers from the rice straw and treating the extracted coarse rice fibers with an enzyme solution. For instance, the enzyme solution may include cellulase and a xylanase preparation. Implementation of the method results in high quality natural cellulose rice fibers which may be suitable for all textile applications that use natural cellulose fibers (e.g., cotton and linen). In addition, extracted rice fibers that are at least ten (10) millimeters in length, no more than 0.5 millimeters in width and include a generally smooth surface are disclosed. For example, textile or composite products may be produced with such rice fibers.
    Type: Application
    Filed: January 24, 2006
    Publication date: August 17, 2006
    Inventors: Yiqi Yang, Narendra Reddy
  • Publication number: 20040068807
    Abstract: The invention relates to new methods of dyeing polymers. The methods include dispersing nanomaterials into the polymers to form polymer nanocomposites, and dyeing the polymer nanocomposites with a dye. The invention also relates to dyed polymers thus obtained and articles made from these dyed polymers.
    Type: Application
    Filed: September 16, 2003
    Publication date: April 15, 2004
    Applicants: University of Massachusetts, a Massachusetts corporation, The Board of Regents of the University of Nebraska, a Nebraska corporation
    Inventors: Qinguo Fan, Yiqi Yang, Samuel C. Ugbolue, Alton R. Wilson
  • Patent number: 6646026
    Abstract: The invention relates to new methods of dyeing polymers. The methods include dispersing nanomaterials into the polymers to form polymer nanocomposites, and dyeing the polymer nanocomposites with a dye. The invention also relates to dyed polymers thus obtained and articles made from these dyed polymers.
    Type: Grant
    Filed: February 7, 2002
    Date of Patent: November 11, 2003
    Assignee: University of Massachusetts
    Inventors: Qinguo Fan, Yiqi Yang, Samuel C. Ugbolue, Alton R Wilson
  • Publication number: 20030158293
    Abstract: The invention relates to new methods of dyeing polymers. The methods include dispersing nanomaterials into the polymers to form polymer nanocomposites, and dyeing the polymer nanocomposites with a dye. The invention also relates to dyed polymers thus obtained and articles made from these dyed polymers.
    Type: Application
    Filed: February 7, 2002
    Publication date: August 21, 2003
    Inventors: Qinguo Fan, Yiqi Yang, Samuel C. Ugbolue, Alton R. Wilson
  • Patent number: 6083283
    Abstract: A method for removing color and extracting dyes from ionically dyeable polymeric materials is provided. The method includes contacting the ionically dyeable polymeric material with a swelling agent for the material under conditions sufficient to effect diffusion of the dye from the material. The process is especially useful for removing colors from ionically dyeable polymeric materials as part of a recycling process for such materials. Also, the extracted dye may be recovered for re-use as the swelling agent and contacting composition are substantially non-reactive with the dye.
    Type: Grant
    Filed: February 6, 1998
    Date of Patent: July 4, 2000
    Assignee: Solutia Inc.
    Inventors: Gordon A. Berkstresser, IV, Richard A. Dunbar, George R. McLellan, Le Moyne W. Plischke, Yiqi Yang