Patents by Inventor Yiquing Xu

Yiquing Xu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and reagents for genetic immunization
    Publication number: 20020072504
    Abstract: DNA vaccines which incorporate genetic sequences encoding sorting signals which direct an expressed antigen to a specific cellular organelle facilitate loading of the antigen onto a Class I or Class II MHC molecule for immune presentation. These vaccines are a nucleic acid construct of a genetic sequence encoding a protein or peptide antigen and a sorting signal which will direct expressed antigen to the ER or endosomal-lysosomal compartments within the cell. The resulting constructs can be used as naked DNA vaccines, packaged in liposomes, or coated onto colloidal gold particles. The construct might also be delivered in an expression vector which is expressed in cells of the organism being immunized.
    Type: Application
    Filed: July 2, 2001
    Publication date: June 13, 2002
    Inventors: Alan Houghton, Shirley M. Bartido, Yiquing Xu, Siqun Wang
  • Method and reagents for genetic immunization
    Patent number: 6294378
    Abstract: DNA vaccines which incorporate genetic sequences encoding sorting signals which direct an expressed antigen to a specific cellular organelle facilitate loading of the antigen onto a Class I or Class II MHC molecule for immune presentation. These vaccines are a nucleic acid construct of a genetic sequence encoding a protein or peptide antigen and a sorting signal which will direct expressed antigen to the ER or endosomal-lysosomal compartments within the cell. The resulting constructs can be used as naked DNA vaccines, packaged in liposomes, or coated onto colloidal gold particles. The construct might also be delivered in an expression vector which is expressed in cells of the organism being immunized.
    Type: Grant
    Filed: June 9, 1999
    Date of Patent: September 25, 2001
    Assignee: Sloan-Kettering Institute for Cancer Research
    Inventors: Alan Houghton, Shirley M. Bartido, Yiquing Xu, Siqun Wang