Patents by Inventor Yitzchak Hillman

Yitzchak Hillman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20150258172
    Abstract: The invention provides methods for the treatment of disease and promotion of healing that include providing a therapeutically effective amount of a mammalian antimicrobial peptide (AMP) or analog thereof, in particular a cathelicidin or cathelicidin fragment or cathelicidin analog, thereby treating the disease in the subject in need thereof. The invention also provides specific analogs or fragments of cathelicidin that function as agonists, as do endogenous cathelicidins, or as either dominant negatives or as inhibitors to endogenous cathelicidin or to other endogenous AMPs or that compete with pro-inflammatory agents or fragments of AMPs on cognate receptors without inducing disease.
    Type: Application
    Filed: April 13, 2015
    Publication date: September 17, 2015
    Inventor: Yitzchak Hillman, SR.
  • Patent number: 9044438
    Abstract: Provided are methods for the treatment of disease and promotion of healing that include providing a therapeutically effective amount of a mammalian antimicrobial peptide (AMP) or analog thereof, in particular a cathelicidin or cathelicidin fragment or cathelicidin analog, thereby treating the disease in the subject in need thereof. Also provided are specific analogs or fragments of cathelicidin that function as agonists, as do endogenous cathelicidins, or as either dominant negatives or as inhibitors to endogenous cathelicidin or to other endogenous AMPs or that compete with pro-inflammatory agents or fragments of AMPs on cognate receptors without inducing disease.
    Type: Grant
    Filed: February 5, 2013
    Date of Patent: June 2, 2015
    Inventor: Yitzchak Hillman
  • Publication number: 20140235544
    Abstract: The invention provides methods for the treatment of disease and promotion of healing that include providing a therapeutically effective amount of a mammalian antimicrobial peptide (AMP) or analog thereof, in particular a cathelicidin or cathelicidin fragment or cathelicidin analog, thereby treating the disease in the subject in need thereof. The invention also provides specific analogs or fragments of cathelicidin that function as agonists, as do endogenous cathelicidins, or as either dominant negatives or as inhibitors to endogenous cathelicidin or to other endogenous AMPs or that compete with pro-inflammatory agents or fragments of AMPs on cognate receptors without inducing disease.
    Type: Application
    Filed: February 15, 2013
    Publication date: August 21, 2014
    Inventor: Yitzchak Hillman
  • Publication number: 20140221278
    Abstract: Provided are methods for the treatment of disease and promotion of healing that include providing a therapeutically effective amount of a mammalian antimicrobial peptide (AMP) or analog thereof, in particular a cathelicidin or cathelicidin fragment or cathelicidin analog, thereby treating the disease in the subject in need thereof. Also provided are specific analogs or fragments of cathelicidin that function as agonists, as do endogenous cathelicidins, or as either dominant negatives or as inhibitors to endogenous cathelicidin or to other endogenous AMPs or that compete with pro-inflammatory agents or fragments of AMPs on cognate receptors without inducing disease.
    Type: Application
    Filed: February 5, 2013
    Publication date: August 7, 2014
    Inventor: Yitzchak Hillman
  • Patent number: 8426366
    Abstract: Provided are methods for the treatment of disease and promotion of healing that include providing a therapeutically effective amount of a mammalian antimicrobial peptide (AMP) or analog thereof, in particular a cathelicidin or cathelicidin fragment or cathelicidin analog, thereby treating the disease in the subject in need thereof. Also provided are specific analogs or fragments of cathelicidin that function as agonists, as do endogenous cathelicidins, or as either dominant negatives or as inhibitors to endogenous cathelicidin or to other endogenous AMPs or that compete with pro-inflammatory agents or fragments of AMPs on cognate receptors without inducing disease.
    Type: Grant
    Filed: April 29, 2012
    Date of Patent: April 23, 2013
    Inventor: Yitzchak Hillman
  • Publication number: 20120277157
    Abstract: Provided are methods for the treatment of disease and promotion of healing that include providing a therapeutically effective amount of a mammalian antimicrobial peptide (AMP) or analog thereof, in particular a cathelicidin or cathelicidin fragment or cathelicidin analog, thereby treating the disease in the subject in need thereof. Also provided are specific analogs or fragments of cathelicidin that function as agonists, as do endogenous cathelicidins, or as either dominant negatives or as inhibitors to endogenous cathelicidin or to other endogenous AMPs or that compete with pro-inflammatory agents or fragments of AMPs on cognate receptors without inducing disease.
    Type: Application
    Filed: April 29, 2012
    Publication date: November 1, 2012
    Inventor: Yitzchak Hillman
  • Patent number: 8202835
    Abstract: The invention provides methods for the treatment of disease and promotion of healing that include providing a therapeutically effective amount of a mammalian antimicrobial peptide (AMP) or analog thereof, in particular a cathelicidin or cathelicidin fragment or cathelicidin analog, thereby treating the disease in the subject in need thereof. The invention also provides specific analogs or fragments of cathelicidin that function as agonists, as do endogenous cathelicidins, or as either dominant negatives or as inhibitors to endogenous cathelicidin or to other endogenous AMPs or that compete with pro-inflammatory agents or fragments of AMPs on cognate receptors without inducing disease.
    Type: Grant
    Filed: July 15, 2008
    Date of Patent: June 19, 2012
    Inventor: Yitzchak Hillman
  • Publication number: 20100297150
    Abstract: A method of treating a disease in a subject in need thereof is disclosed. The method comprises providing to the subject a therapeutically effective amount of a compound being capable of decreasing an activity and/or level of an antimicrobial peptide (AMP) and/or AMP-like molecule, thereby treating the disease in the subject in need thereof.
    Type: Application
    Filed: August 5, 2010
    Publication date: November 25, 2010
    Inventor: Yitzchak Hillman
  • Publication number: 20090048167
    Abstract: The invention provides methods for the treatment of disease and promotion of healing that include providing a therapeutically effective amount of a mammalian antimicrobial peptide (AMP) or analog thereof, in particular a cathelicidin or cathelicidin fragment or cathelicidin analog, thereby treating the disease in the subject in need thereof. The invention also provides specific analogs or fragments of cathelicidin that function as agonists, as do endogenous cathelicidins, or as either dominant negatives or as inhibitors to endogenous cathelicidin or to other endogenous AMPs or that compete with pro-inflammatory agents or fragments of AMPs on cognate receptors without inducing disease.
    Type: Application
    Filed: July 15, 2008
    Publication date: February 19, 2009
    Inventor: YITZCHAK HILLMAN
  • Patent number: 7428323
    Abstract: A method and system for automatic diagnosis of possible brain disease is based on at least one brain scan image of a patient containing at least one feature of interest and a corresponding result of a medical profile analysis of the patient. A database containing parameters associated with at least one feature of a plurality of brain scan images each compiled from respective patient data and inserted into the database is searched so as to extract from the database a set of respective parameters each associated with the at least one feature and wherein in respect of each feature at least one of the corresponding parameters is indicative of a brain disease profile. The set of respective parameters is analyzed to determine a statistically significant brain disease profile which fits the patient based on the at least one feature of interest of the patient's brain scan image.
    Type: Grant
    Filed: January 19, 2006
    Date of Patent: September 23, 2008
    Inventor: Yitzchak Hillman
  • Publication number: 20060120584
    Abstract: A method and system for automatic diagnosis of possible brain disease is based on at least one brain scan image of a patient containing at least one feature of interest and a corresponding result of a medical profile analysis of the patient. A database containing parameters associated with at least one feature of a plurality of brain scan images each compiled from respective patient data and inserted into the database is searched so as to extract from the database a set of respective parameters each associated with the at least one feature and wherein in respect of each feature at least one of the corresponding parameters is indicative of a brain disease profile. The set of respective parameters is analyzed to determine a statistically significant brain disease profile which fits the patient based on the at least one feature of interest of the patient's brain scan image.
    Type: Application
    Filed: January 19, 2006
    Publication date: June 8, 2006
    Inventor: Yitzchak Hillman
  • Publication number: 20060115480
    Abstract: A method of treating a disease in a subject in need thereof is disclosed. The method comprises providing to the subject a therapeutically effective amount of a compound being capable of decreasing an activity and/or level of an antimicrobial peptide (AMP) and/or AMP-like molecule, thereby treating the disease in the subject in need thereof.
    Type: Application
    Filed: December 21, 2003
    Publication date: June 1, 2006
    Inventor: Yitzchak Hillman
  • Publication number: 20040013291
    Abstract: A method for psychiatric profiling comprising: (a) obtaining a 3-D brain scan image (and its enhancement parameters) and obtaining a psychiatric profile analysis; (b) extracting the edges of the scan, pinpointing reference points on it, positioning, standardizing, and aligning it; (c) autocropping, extracting a plurality of features and/or regions within the scan; (d) correlating said regions or features with database images and parameters; (e) searching a message memory for messages that make up an individual's profile (said messages correspond to feature/s of a database), outputting each message to form a first profile set of messages; (f) obtaining a second set of feature detections and message statements; (g) accepting output detections and related messages in the first set to form a third profile set (a subset of the first set), combining the second and third profile to form a fourth set, alternatively allowing the fourth set to equal the first set, alternatively allowing the third set to equal the secon
    Type: Application
    Filed: May 14, 2003
    Publication date: January 22, 2004
    Inventor: Yitzchak Hillman