Abstract: Systems and methods are provided for performing multi-analyte testing. In some embodiments, an analyte testing device is provided that includes a plurality of modules, each module of the plurality of modules configured to perform one or more of a plurality of different analyte tests. Each module of the plurality of modules includes at least one sample port for receiving a sample, and at least one microprocessor configured to calculate an amount of one or more different analytes in the sample and prepare test results based on the calculated one or more different analytes. A base unit is provided having a plurality of receptacles configured to receive the plurality of modules such that an electrical connection is established therebetween. Each module of the plurality of modules is configured to utilize the electrical connection to communicate the test results from each module to a processor of the base unit.