Patents by Inventor Yitzhak Koch

Yitzhak Koch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and pharmaceutical compositions for GnRH-I and GnRH-II modulation of T-cell activity, adhesion, migration and extravasation
    Patent number: 7951775
    Abstract: Methods and compositions comprising GnRH-I and GnRH-II, GnRH-I and GnRH-II antibodies, anti-receptor antibodies, polynucleotide constructs and GnRH-I and GnRH-II analogs for immune enhancement and suppression, prevention and treatment of diseases and conditions characterized by abnormal T-cell activity, treatment of viral and prion-related diseases, and treatment of T-cell related neoplastic diseases are disclosed.
    Type: Grant
    Filed: December 17, 2002
    Date of Patent: May 31, 2011
    Inventors: Mia Levite, Yitzhak Koch
  • Long-acting gonadotropin-releasing hormone analogs and methods of use thereof
    Publication number: 20060100154
    Abstract: The present invention relates to the design, synthesis and biological evaluation of potent long-acting gonadotropin-releasing hormone (GnRH) analogs including agonists and antagonists comprising a GnRH peptide conjugated to emodic acid or an emodic acid derivative. These long acting analogs bind to GnRH receptors with high affinity and are devoid of any toxicity or antiproliferative effects. The present invention further relates to therapeutic uses of these GnRII analogs as contraceptives, in controlling fertility and in treating and/or preventing sex-hormone dependent diseases or conditions.
    Type: Application
    Filed: October 13, 2005
    Publication date: May 11, 2006
    Applicant: YEDA RESEARCH AND DEVELOPMENT CO
    Inventors: Yitzhak Koch, Matityahu Fridkin, Shai Rahimipour
  • Methods and pharmaceutical compositions for gnrh-II and gnrh-II modulation of t-cell activity, adhesion, migration and extravasation
    Publication number: 20050158309
    Abstract: Methods and compositions comprising GnRH-I and GnRH-II, GnRH-I and GnRH-II antibodies, anti-receptor antibodies, polynucleotide constructs and GnRH-I and GnRH-II analogs for immune enhancement and suppression, prevention and treatment of diseases and conditions characterized by abnormal T-cell activity, treatment of viral and prion-related diseases, and treatment of T-cell related neoplastic diseases are disclosed.
    Type: Application
    Filed: December 17, 2002
    Publication date: July 21, 2005
    Inventors: Mia Levite, Yitzhak Koch