Abstract: The present disclosure relates to thermoplastic resin modifier compositions, methods for converting the compositions into functional resins, and to plastic articles prepared from the resins.

Abstract: A portable and completely self-contained apparatus(20) for detecting analyte and the methods of use thereof is described. The apparatus (20) includes a microfluidic cartridge driver unit (30), an optical inspection unit (32), and a control unit (28) and a power supply unit, which can run the binding and detection of the analyte without any fluidic interfaces to the instrument. The microfluidic cartridge driver unit (30) receives microfluidic cartridge (22) that holds a microarray and integrated microfluidic chip (24) for delivering the analyte to perform different process steps in the detection of analyte. A complete detection of analyte using the invention takes only a few minutes.

Abstract: This invention discloses a transparent standalone resin or masterbatch concentrate composition and manufacturing method of transforming commercial transparent grade base thermoplastics into anti-biofouling resins through extrusion or any similar hot melt mixing processes. The re-compound solids enable a number of product reforming processes, including but not limited to thermoforming, profile extrusion, injection molding, blow molding, blow filming, film casting, and spinning into articles of different shapes and geometries or overmolding on plastic substrates that can resist surface adsorption of microbes, mammalian cells, proteins, peptides, nucleic acids, steroids and other cellular constituents after solidification. The articles formed thereof additionally exhibit mechanical reinforcement and no leaching while retain the optical clarity of the base thermoplastics in the same product form as quantified in terms of the light transmittance and haze.

Abstract: This invention discloses a transparent standalone resin or masterbatch concentrate composition and manufacturing method of transforming commercial transparent grade base thermoplastics into anti-biofouling resins through extrusion or any similar hot melt mixing processes. The re-compound solids enable a number of product reforming processes, including but not limited to thermoforming, profile extrusion, injection molding, blow molding, blow filming, film casting, and spinning into articles of different shapes and geometries or overmolding on plastic substrates that can resist surface adsorption of microbes, mammalian cells, proteins, peptides, nucleic acids, steroids and other cellular constituents after solidification. The articles formed thereof additionally exhibit mechanical reinforcement and no leaching while retain the optical clarity of the base thermoplastics in the same product form as quantified in terms of the light transmittance and haze.

Abstract: Provided herein is a method for preparing antimicrobial thermoplastic resins and products thereof.

Abstract: A built-in and process-adaptive formulation of antimicrobial commodity thermoplastic resins with mixed compositions comprising of a polymer, a backbone linker, and a non-labile antifouling and biocompatible coupling agent which is melt-processable and enabled to be manufactured into finished products in the form of solid, monolith, tube, composite, fiber, film, sheet and varnish without the prerequisite of biocides or antimicrobial additives is disclosed. The said formulation is adapted to thermoforming and thermal curing processes including but not limited to melt compounding, spinning, extrusion, molding, compression foaming and drawing. The antimicrobial property is attributed to the persistent formation of a non-stick bacteria-repellent tethered layer in which the antifouling component of the said formulation is heterogeneously phase separated and/or surface migrated to the surface after product forming in order to minimize adsorption and/or colonization of bacteria.

Abstract: A built-in and process-adaptive formulation of antimicrobial commodity thermoplastic resins with mixed compositions comprising of a polymer, a backbone linker, and a non-labile antifouling and biocompatible coupling agent which is melt-processable and enabled to be manufactured into finished products in the form of solid, monolith, tube, composite, fiber, film, sheet and varnish without the prerequisite of biocides or antimicrobial additives is disclosed. The said formulation is adapted to thermoforming and thermal curing processes including but not limited to melt compounding, spinning, extrusion, molding, compression foaming and drawing. The antimicrobial property is attributed to the persistent formation of a non-stick bacteria-repellent tethered layer in which the antifouling component of the said formulation is heterogeneously phase separated and/or surface migrated to the surface after product forming in order to minimize adsorption and/or colonization of bacteria.

Abstract: This invention discloses a transparent standalone resin or masterbatch concentrate composition and manufacturing method of transforming commercial transparent grade base thermoplastics into anti-biofouling resins through extrusion or any similar hot melt mixing processes. The re-compound solids enable a number of product reforming processes, including but not limited to thermoforming, profile extrusion, injection molding, blow molding, blow filming, film casting, and spinning into articles of different shapes and geometries or overmolding on plastic substrates that can resist surface adsorption of microbes, mammalian cells, proteins, peptides, nucleic acids, steroids and other cellular constituents after solidification. The articles formed thereof additionally exhibit mechanical reinforcement and no leaching while retain the optical clarity of the base thermoplastics in the same product form as quantified in terms of the light transmittance and haze.

Abstract: The present invention generally relates to a thermoplastic resin which is functionalized by an initiator- or linker-free process and imparted with functional properties, and related methods of fabrication. In particular, the present invention relates to methods of covalently modifying the thermoplastic resin using plasma before or after being introduced with an active agent having said functional properties.

Abstract: A portable and completely self-contained apparatus(20) for detecting analyte and the methods of use thereof is described. The apparatus (20) includes a microfluidic cartridge driver unit (30), an optical inspection unit (32), and a control unit (28) and a power supply unit, which can run the binding and detection of the analyte without any fluidic interfaces to the instrument. The microfluidic cartridge driver unit (30) receives microfluidic cartridge (22) that holds a microarray and integrated microfluidic chip (24) for delivering the analyte to perform different process steps in the detection of analyte. A complete detection of analyte using the invention takes only a few minutes.

Abstract: A built-in and process-adaptive formulation of antimicrobial commodity thermoplastic resins with mixed compositions comprising of a polymer, a backbone linker, and a non-labile antifouling and biocompatible coupling agent which is melt-processable and enabled to be manufactured into finished products in the form of solid, monolith, tube, composite, fiber, film, sheet and varnish without the prerequisite of biocides or antimicrobial additives is disclosed. The said formulation is adapted to thermoforming and thermal curing processes including but not limited to melt compounding, spinning, extrusion, molding, compression foaming and drawing. The antimicrobial property is attributed to the persistent formation of a non-stick bacteria-repellent tethered layer in which the antifouling component of the said formulation is heterogeneously phase separated and/or surface migrated to the surface after product forming in order to minimize adsorption and/or colonization of bacteria.