Abstract: An optofluidic device includes: a housing having an inlet port coupled to an inlet side and an outlet port coupled to an outlet side; and a microlens disposed within the housing between the inlet side and the outlet side. A fluid having a plurality of particles flows from the inlet side through the microlens to the outlet side. The optofluidic device further includes a light source configured to emit a light beam in a direction opposite flow direction of the fluid, the light beam defining an optical axis that is perpendicular to the microlens.

Abstract: The present invention relates to the biomedicine field, in particular to an anti-human PD-L1 humanized monoclonal antibody and its applications. The invention obtains an anti-human PD-L1 humanized monoclonal antibody with good specificity, high affinity and stability by screening, and the antibody can specifically bind to human PD-L1 instead of binding to members of B7 family, and it can bind to active T-cells to strengthen the activation of T-cells, so it can significantly inhibit the growth of tumor.

Abstract: The present invention relates to the biomedicine field, in particular to an anti-human PD-1 humanized monoclonal antibody and its applications. The invention obtains an anti-human PD-1 humanized monoclonal antibody with good specificity, high affinity and stability by screening, and the antibody can specifically bind to human PD-1 instead of binding to other members of CD28 family, block the binding of PD-L1 and PD-1 with CD80 and partially restore functions of T-cells, so it can significantly inhibit the growth of tumor.

Abstract: The present invention relates to the biomedicine field, in particular to an anti-human PD-L1 humanized monoclonal antibody and its applications. The invention obtains an anti-human PD-L1 humanized monoclonal antibody with good specificity, high affinity and stability by screening, and the antibody can specifically bind to human PD-L1 instead of binding to members of B7 family, and it can bind to active T-cells to strengthen the activation of T-cells, so it can significantly inhibit the growth of tumor.

Abstract: The present invention relates to the biomedicine field, in particular to an anti-human PD-1 humanized monoclonal antibody and its applications. The invention obtains an anti-human PD-1 humanized monoclonal antibody with good specificity, high affinity and stability by screening, and the antibody can specifically bind to human PD-1 instead of binding to other members of CD28 family, block the binding of PD-L1 and PD-1 with CD80 and partially restore functions of T-cells, so it can significantly inhibit the growth of tumor.

Abstract: The present invention provides a stratigraphic correlation method and apparatus based on uncertainty. The stratigraphic correlation method comprises: determining a plurality of possible correlation positions in a well with uncertain layered position in a profile, in a stratigraphic correlation process; assigning a qualitative or quantitative certainty value to the plurality of correlation positions; and storing and displaying the plurality of correlation positions and certainty values thereof as different layered solutions on the profile, respectively. By setting a plurality of position solutions for a layer in the present invention, all possibilities of the layered position judged by the geological personnel can be recorded as references for the subsequent correlation of other profiles, the closing of the whole layered solution, and the quality control.

Abstract: The present invention discloses a method and an apparatus for predicting performance profiles of multi-layered oil reservoirs, wherein the method comprises: dividing the multi-layered oil reservoirs into a plurality of blocks, and determining a reservoir type, formation factor Kh and an evaluated reserves of each layer in each block; selecting a block representing geologic features of the multi-layered oil reservoirs from the plurality of blocks as a representative block, to build a fine geological model of the representative block; building corresponding fine numerical simulation model according to the fine geological model of the representative block, and determining type curves of different reservoir types under different development strategies; determining a relation curve between Kh and well injection rate for injectors and a relation curve between Kh and well production rate for producers in the multi-layered oil reservoirs under different restrictive conditions; predicting performance of the multi-laye