Patents by Inventor YiXin Zhang

YiXin Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240123058
    Abstract: Provided are an epitope peptide (or a variant thereof) that can be used for preventing or treating an EBV infection, a recombinant protein containing the epitope peptide (or variant thereof) and a carrier protein, and the use of the epitope peptide (or variant thereof) and the recombinant protein. Further provided are an antibody against the epitope peptide, and the use thereof in the detection, prevention and/or treatment of an EBV infection and/or diseases caused by the infection.
    Type: Application
    Filed: January 29, 2022
    Publication date: April 18, 2024
    Inventors: Yixin CHEN, Xiao ZHANG, Junping HONG, Miao XU, Qian WU, Ling ZHONG, Ningshao XIA
  • Patent number: 11918900
    Abstract: This application discloses a scene recognition method and apparatus, which may be applied to game scene recognition. The method includes: obtaining one or more drawing instructions, and determining a to-be-drawn target object based on a description parameter carried in the one or more drawing instructions. Based on a particular relationship between scenes and an object inside scenes, a corresponding target scene may be determined based on the target object.
    Type: Grant
    Filed: July 30, 2021
    Date of Patent: March 5, 2024
    Assignee: HUAWEI TECHNOLOGIES CO., LTD.
    Inventors: Fan Zhang, Yixin Deng, Baocheng Gu, Dong Wei, Shengqiang Ke
  • Publication number: 20240039227
    Abstract: A distributed weak grating array sensing system and method with multiple demodulation modes are provided for optical fiber sensing.
    Type: Application
    Filed: March 3, 2023
    Publication date: February 1, 2024
    Applicant: NANJING UNIVERSITY
    Inventors: Feng WANG, Rui HONG, Xuping ZHANG, Yixin ZHANG
  • Patent number: 11860008
    Abstract: A self-heterodyne phase-sensitive optical time domain reflectometry (?-OTDR) system with a free multi-spatial resolution includes a narrow linewidth laser source, a 1×3 fiber-optic coupler, three acousto-optic modulators (AGMs), a 3×1 fiber-optic coupler, two time-delay fibers, an erbium-doped fiber amplifier (EDFA), a circulator, a photodetector, an electrical amplifier, three filters, a data acquisition card, a pulse signal generator, and a driver module. A plurality of acousto-optic modulators using the same driver are used to couple probe light with different pulse intervals and different frequency shifts and then inject the probe light into a fiber, such that a self-heterodyne detection structure with a multi-spatial resolution is implemented, which suppressed optical background noise such as coherent fading noise, phase noise introduced by a frequency drift of a light source, and pseudo-random noise (PRN).
    Type: Grant
    Filed: May 6, 2022
    Date of Patent: January 2, 2024
    Assignee: NANJING UNIVERSITY
    Inventors: Yixin Zhang, Jinyu Song, Xuping Zhang, Zhewen Ding, Shuai Tong, Shun Wang, Feng Wang
  • Patent number: 11804316
    Abstract: The invention discloses an underwater umbilical cable which is capable of temperature and vibration measuring and three-dimensional shape reconstruction, wherein underwater umbilical cable is used to connect underwater equipment and aquatic equipment; the underwater umbilical cable comprises an outer sheath, armored steel wires, an inner sheath, a power cable, a communication optical cable, a steel pipe, three strain measuring optical fibers, three temperature measuring optical fibers, a distributed optical fiber strain interrogator, a distributed optical fiber temperature interrogator and a processor. The invention can collect the operation status data of the umbilical cable for a long time. The collected data is highly objective, can truly reflect the real-time operation status of the umbilical cables, and plays an important role in guaranteeing the long-term submarine oil and gas exploitation.
    Type: Grant
    Filed: June 15, 2022
    Date of Patent: October 31, 2023
    Inventors: Yixin Zhang, Fei Xiong, Xuping Zhang, Chi Zhang, Long Chen, Shun Wang, Xiaohong Chen, Feng Wang
  • Publication number: 20230314188
    Abstract: A self-heterodyne phase-sensitive optical time domain reflectometry (?-OTDR) system with a free multi-spatial resolution includes a narrow linewidth laser source, a 1×3 fiber-optic coupler, three acousto-optic modulators (AOMs), a 3×1 fiber-optic coupler, two time-delay fibers, an erbium-doped fiber amplifier (EDFA), a circulator, a photodetector, an electrical amplifier, three filters, a data acquisition card, a pulse signal generator, and a driver module. A plurality of acousto-optic modulators using the same driver are used to couple probe light with different pulse intervals and different frequency shifts and then inject the probe light into a fiber, such that a self-heterodyne detection structure with a multi-spatial resolution is implemented, which suppressed optical background noise such as coherent fading noise, phase noise introduced by a frequency drift of a light source, and pseudo-random noise (PRN).
    Type: Application
    Filed: May 6, 2022
    Publication date: October 5, 2023
    Applicant: NANJING UNIVERSITY
    Inventors: Yixin ZHANG, Jinyu SONG, Xuping ZHANG, Zhewen DING, Shuai TONG, Shun WANG, Feng WANG
  • Publication number: 20230273092
    Abstract: A method for suppressing coherent and polarization-induced fading by simultaneous monitoring of loss and vibration is provided. By using merely common single-mode sensing fibers, the polarization diversity-based measurement method solves the conflict between ?-OTDR and COTDR in terms of polarization state. In addition, the method not only achieves a better coherent fading noise suppression effect but also enhances the capability of recognizing small loss events in the monitoring of loss parameters. Meanwhile, the method can suppress the influence of coherent fading on the phase demodulation of ?-OTDR and reconstruct a vibration signal with high fidelity in the monitoring of perturbation parameters, which can effectively reduce the error rate of external perturbation warning.
    Type: Application
    Filed: March 23, 2022
    Publication date: August 31, 2023
    Applicant: NANJING UNIVERSITY
    Inventors: Yixin ZHANG, Xiaohong CHEN, Xuping ZHANG, Shuai TONG, Lei LIANG, Yiming WAN, Feng WANG
  • Publication number: 20230212788
    Abstract: The invention provides an amphiphilic coating for the direct and rapid synthesis of an array of peptides and small molecular compounds on a planar surface of a solid support, comprising a hydrophilic chemical structure and a lipophilic group, wherein said peptides and small molecular compounds differ from spot to spot from each other in the chemical structure, characterized in that said amphiphilic coating possesses low wettability to polar aprotic solvents used in the array synthesis; said amphiphilic coating possessing low wettability is designed that it can be converted to a coating possessing high wettability by hydrolysis of the lipophilic group; and said amphiphilic coating comprises an amino group for the reaction with an electrophilic reagent.
    Type: Application
    Filed: March 24, 2021
    Publication date: July 6, 2023
    Inventors: Yixin ZHANG, Weilin LIN
  • Publication number: 20230154653
    Abstract: The invention discloses an underwater umbilical cable which is capable of temperature and vibration measuring and three-dimensional shape reconstruction, wherein underwater umbilical cable is used to connect underwater equipment and aquatic equipment; the underwater umbilical cable comprises an outer sheath, armored steel wires, an inner sheath, a power cable, a communication optical cable, a steel pipe, three strain measuring optical fibers, three temperature measuring optical fibers, a distributed optical fiber strain interrogator, a distributed optical fiber temperature interrogator and a processor. The invention can collect the operation status data of the umbilical cable for a long time. The collected data is highly objective, can truly reflect the real-time operation status of the umbilical cables, and plays an important role in guaranteeing the long-term submarine oil and gas exploitation.
    Type: Application
    Filed: June 15, 2022
    Publication date: May 18, 2023
    Inventors: Yixin Zhang, Fei Xiong, Xuping Zhang, Chi Zhang, Long Chen, Shun Wang, Xiaohong Chen, Feng Wang
  • Patent number: 11648320
    Abstract: The present invention provides a biomatrix layer comprising, consisting essentially of or consisting of a sulfated oligosaccharide at a concentration in the range of 0.1 ?M to 1,000 ?M and a peptide-polyethylene glycol-conjugate according to formula (I): PEG-R1-(BX)n (I) wherein B is lysine or arginine, X is selected from alanine, glycine, serine, threonine, tyrosine, glutamic acid or aspartic acid and n is an integer selected from 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19 and 20; R1 may be absent or is a peptide comprising 5 to 30 amino acids; PEG is comprised at a concentration in the range of 0.1 ?M to 1,000 ?M; R1, if present, is comprised at a concentration in the range of 0.1 ?M to 4,000 ?M; (BX)n is comprised at a concentration in the range of 0.25 ?M to 1,000 ?M. The invention further relates to processes for assembling the biomatrix layer.
    Type: Grant
    Filed: June 18, 2018
    Date of Patent: May 16, 2023
    Assignee: DENOVOMATRIX GMBH
    Inventors: Yixin Zhang, Alvin Thomas, Richard Wetzel, Dejan Husman, Robert Wieduwild
  • Patent number: 11523990
    Abstract: The invention relates to a hydrogel matrix comprising a mixture of a covalent peptide-polymer conjugate and an oligosaccharide; wherein the oligosaccharide is a highly negatively charged sulfated oligosaccharide selected from the group consisting of heparin, dextran sulfate, ?-cyclodextrin sulfate, ?-cyclodextrin sulfate and ?-cyclodextrin sulfate; wherein said polymer comprised in said peptide-polymer conjugate is a linear or multi-arm polyethylene glycol; wherein said peptide comprised in said peptide-polymer conjugate is a peptide, which consists of an amino acid sequence selected from the group consisting of SEQ ID NO.4, SEQ ID NO.5, SEQ ID NO. 18 and SEQ ID NO. 19; and wherein said hydrogel matrix is configured in the form of an oligosaccharide/peptide/polymer system, in which said peptide is chemically conjugated to the polymer such that the hydrogel is obtained by mixing the peptide-polymer conjugate and the oligosaccharide.
    Type: Grant
    Filed: September 4, 2019
    Date of Patent: December 13, 2022
    Assignee: DENOVOMATRIX GMBH
    Inventors: Robert Wieduwild, Yixin Zhang, Carsten Werner, Mikhail Tsurkan, Uwe Freudenberg
  • Patent number: 11473134
    Abstract: A method for the deconvolution of nucleic acid-containing substance mixtures using synthetically generated target nucleotide sequences. Starting from a plurality of nucleotides,, a plurality of different target nucleotide sequences (TNS) is generated according to a predetermined algorithm. At least one of the TNS generated is associated with at least one substance or substance combination and chemically coupled thereto. At least one substance mixture to be analysed and having at least two different TNS is provided and is sequenced according to a sequencing method., at the same time all TNS contained in the substance mixture are detected in a common sequence spectrum. To facilitate the deconvolution, the sequence spectra of a substance mixture should be deducted/subtracted from each other prior to and after a selection experiment.
    Type: Grant
    Filed: January 12, 2015
    Date of Patent: October 18, 2022
    Assignee: DYNABIND GMBH
    Inventors: Yixin Zhang, Jana Herrmann, Robert Wieduwild, Annett Berthold
  • Publication number: 20220298552
    Abstract: The present invention relates to a method for the sensitive identification of high-affinity complexes made of two ligands (2, 3, 4, 5, 6, 7) and one receptor (1). A large number of different ligands (2, 3, 4, 5, 6, 7) of a chemical library are hereby contacted with at least one receptor (1) in a solution. The ligands of the library have a single-strand DNA (8, 9) or RNA with a base length of 2 to 10 bases or alternatively more than 10 bases. In addition, the solution is incubated for a specific period of time and complexes made of two ligands (2, 3, 4, 5, 6, 7) and one receptor (1) are identified.
    Type: Application
    Filed: June 7, 2022
    Publication date: September 22, 2022
    Applicant: DYNABIND GMBH
    Inventors: Francesco REDDAVIDE, Helena DE ANDRADE, Weilin LIN, Yixin ZHANG
  • Patent number: 11431263
    Abstract: Disclosed is a solid-state transformer having an uninterrupted operation ability under an AC/DC fault, in which bridge arms of a hybrid modular multilevel converter include half-bridge submodules and full-bridge submodules. The half-bridge submodules and the full-bridge submodules are connected with input ends of isolated dual-active-bridge converters via DC capacitors of the half-bridge submodules and full-bridge submodules; output ends of the isolated dual-active-bridge converters are connected in parallel to form a low-voltage DC bus; and a three-phase full-bridge inverter is connected to the low-voltage DC bus. The solid-state transformer may be provided with four ports including a medium-voltage AC port, a medium-voltage DC port, a low-voltage DC port and a low-voltage AC port which are beneficial to the interconnection of multi-voltage-level and multi-form AC/DC hybrid distribution grids. The solid-state transformer has the uninterrupted operation ability under the AC/DC fault.
    Type: Grant
    Filed: February 9, 2022
    Date of Patent: August 30, 2022
    Assignee: SHANGHAI JIAO TONG UNIVERSITY
    Inventors: Jianwen Zhang, Yixin Zhang, Weixin Fang, Jianqiao Zhou, Gang Shi, Xu Cai, Jiacheng Wang
  • Patent number: 11365439
    Abstract: The present invention relates to a method for the sensitive identification of high-affinity complexes made of two ligands (2, 3, 4, 5, 6, 7) and one receptor (1). A large number of different ligands (2, 3, 4, 5, 6, 7) of a chemical library are hereby contacted with at least one receptor (1) in a solution. The ligands of the library have a single-strand DNA (8, 9) or RNA with a base length of 2 to 10 bases or alternatively more than 10 bases. In addition, the solution is incubated for a specific period of time and complexes made of two ligands (2, 3, 4, 5, 6, 7) and one receptor (1) are identified.
    Type: Grant
    Filed: July 10, 2015
    Date of Patent: June 21, 2022
    Assignee: DYNABIND GMBH
    Inventors: Francesco Reddavide, Helena De Andrade, Weilin Lin, Yixin Zhang
  • Publication number: 20220166343
    Abstract: In a solid-state transformer having an uninterrupted operation ability under an AC/DC fault, bridge arms of a hybrid modular multilevel converter comprise half-bridge submodules and full-bridge submodules, the half-bridge submodules and the full-bridge submodules are interconnected with input ends of the isolated dual-active-bridge converters via DC capacitors of the submodules, output ends of the plurality of isolated dual-active-bridge converters are connected in parallel to form a low-voltage DC bus, and the three-phase full-bridge inverter is connected to the low-voltage DC bus. The solid-state transformer provided by the present invention may be provided with four ports including a medium-voltage AC port, a medium-voltage DC port, a low-voltage DC port and a low-voltage AC port which are beneficial to the interconnection of multi-voltage-grade and multi-form AC/DC hybrid distribution grids; and the solid-state transformer has the uninterrupted operation ability under the AC/DC fault.
    Type: Application
    Filed: February 9, 2022
    Publication date: May 26, 2022
    Applicant: SHANGHAI JIAO TONG UNIVERSITY
    Inventors: Jianwen ZHANG, Yixin ZHANG, Weixin FANG, Jianqiao ZHOU, Gang SHI, Xu CAI, Jiacheng WANG
  • Patent number: 11214564
    Abstract: The present invention relates to novel compounds as new chemical entities with thymine skeleton, these compounds for use as in medicine, especially in the treatment of carcinoma, HSP27-associated diseases and cystic fibrosis; and a pharmaceutical product containing at least one of these compounds. Finally, a method of production of that novel compounds is presented. General formula of these compounds is formula (I): as further defined in claim 1.
    Type: Grant
    Filed: November 3, 2020
    Date of Patent: January 4, 2022
    Assignee: TECHNISCHE UNIVERSITÄT DRESDEN
    Inventors: Michael Schroeder, Yixin Zhang, Jörg-Christian Heinrich, Joachim Haupt, Petra Lennig
  • Patent number: D998551
    Type: Grant
    Filed: August 9, 2022
    Date of Patent: September 12, 2023
    Inventors: Long Qin, Wenlong Lin, Jingbo Qin, Yixin Zhang, Jingjing Liu, Wen Sun, Junjie Liu
  • Patent number: D998553
    Type: Grant
    Filed: August 9, 2022
    Date of Patent: September 12, 2023
    Inventors: Long Qin, Wenlong Lin, Jingbo Qin, Yixin Zhang, Wen Sun, Jingjing Liu, Junjie Liu
  • Patent number: D1012004
    Type: Grant
    Filed: August 9, 2022
    Date of Patent: January 23, 2024
    Inventors: Long Qin, Wenlong Lin, Jingbo Qin, Jingjing Liu, Yixin Zhang, Sufang Wan, Xuhai Huang