Patents by Inventor Yiyan Yao

Yiyan Yao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TRIFLUOROMETHYL-SUBSTITUTED SULFONAMIDE AS BCL-2-SELECTIVE INHIBITOR
    Publication number: 20250257064
    Abstract: Disclosed is a trifluoromethyl-substituted sulfonamide BCL-2-selective inhibitor, in particular disclosed are a compound of formula I, a stereoisomer or a pharmaceutically acceptable salt thereof, a preparation method therefore, and a pharmaceutical composition thereof. Also disclosed are the uses of said compound and of a pharmaceutical composition comprising same for treating anti-apoptotic BCL-2-related diseases, such as cancer.
    Type: Application
    Filed: April 18, 2025
    Publication date: August 14, 2025
    Inventors: Fei Liu, Weiwei Feng, Bin Wang, Hongjiang Xu, Jinan Wang, Xiquan Zhang, Shanchun Wang, Yanlong Liu, Jianqing Zhang, Yiyan Yao, Xujing Tang, Wei Shi, Hongying Zhang, Yang Li, Song Tang, Yizhong Zhu, Limin Liu, Hongmei Gu, Ling Yang
  • Trifluoromethyl-substituted sulfonamide as BCL-2-selective inhibitor
    Patent number: 12371431
    Abstract: Disclosed is a trifluoromethyl-substituted sulfonamide BCL-2-selective inhibitor, in particular disclosed are a compound of formula I, a stereoisomer or a pharmaceutically acceptable salt thereof, a preparation method therefor, and a pharmaceutical composition thereof. Also disclosed are the uses of said compound and of a pharmaceutical composition comprising same for treating anti-apoptotic BCL-2-related diseases, such as cancer.
    Type: Grant
    Filed: October 29, 2019
    Date of Patent: July 29, 2025
    Assignee: Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
    Inventors: Fei Liu, Weiwei Feng, Bin Wang, Hongjiang Xu, Jinan Wang, Xiquan Zhang, Shanchun Wang, Yanlong Liu, Jianqing Zhang, Yiyan Yao, Xujing Tang, Wei Shi, Hongying Zhang, Yang Li, Song Tang, Yizhong Zhu, Limin Liu, Hongmei Gu, Ling Yang
  • CRYSTAL OF TRIFLUOROMETHYL/CHLORO DISUBSTITUTED SULFONAMIDE SELECTIVE BCL-2 INHIBITOR
    Publication number: 20230174528
    Abstract: A crystal of a trifluoromethyl/chloro disubstituted sulfonamide selective BCL-2 inhibitor, specifically related to a crystal of a compound of formula I, a preparation method therefor, and use thereof in preventing and treating diseases related to anti-apoptotic protein BCL-2, such as cancers.
    Type: Application
    Filed: April 29, 2021
    Publication date: June 8, 2023
    Applicant: CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.
    Inventors: Weiwei FENG, Yanlong LIU, Huihui ZHANG, Fei LIU, Bin WANG, Yiyan YAO, Zhilin CHEN, Jinlei ZHU, Chenghui LU
  • TRIFLUOROMETHYL-SUBSTITUTED SULFONAMIDE AS BCL-2-SELECTIVE INHIBITOR
    Publication number: 20220002290
    Abstract: Disclosed is a trifluoromethyl-substituted sulfonamide BCL-2-selective inhibitor, in particular disclosed are a compound of formula I, a stereoisomer or a pharmaceutically acceptable salt thereof, a preparation method therefor, and a pharmaceutical composition thereof. Also disclosed are the uses of said compound and of a pharmaceutical composition comprising same for treating anti-apoptotic BCL-2-related diseases, such as cancer.
    Type: Application
    Filed: October 29, 2019
    Publication date: January 6, 2022
    Inventors: Fei Liu, Weiwei Feng, Bin Wang, Hongjiang Xu, Jinan Wang, Xiquan Zhang, Shanchun Wang, Yanlong Liu, Jianqing Zhang, Yiyan Yao, Xujing Tang, Wei Shi, Hongying Zhang, Yang Li, Song Tang, Yizhong Zhu, Limin Liu, Hongmei Gu, Ling Yang