Patents by Inventor Yiyuan YIN

Yiyuan YIN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250199010
    Abstract: Provided herein, in some aspects, are binding molecules including co-binders having high affinity and/or high specificity to a target.
    Type: Application
    Filed: December 29, 2021
    Publication date: June 19, 2025
    Applicant: Alamar Biosciences, Inc.
    Inventors: Yiyuan YIN, Yuling LUO, Adrian GRZYBOWSKI
  • Publication number: 20250177523
    Abstract: Provided are, inter alia, multispecific antigen binding proteins, or antigen-binding fragments thereof, comprising one or more mutations in the VH/VL domains and/or CH1/CL domains, pharmaceutical compositions comprising same, isolated nucleic acids, vectors, and host cells encoding/expressing same, method of making the multispecific antigen binding proteins, computer readable media for evaluating multispecific antigen binding proteins, and libraries.
    Type: Application
    Filed: October 14, 2024
    Publication date: June 5, 2025
    Applicant: Genentech, Inc.
    Inventors: Paul CARTER, Christoph SPIESS, Yiyuan YIN, Jianhui ZHOU, Wendy SANDOVAL, Jacob CORN, Michael DILLON
  • Publication number: 20250138000
    Abstract: Disclosed herein are highly sensitive immunoassays that utilize a capture/release mechanism to reduce non-specific binding and achieve detection with attomolar-level sensitivity. Kits that can be used for carrying out these highly sensitive immunoassays are also disclosed herein.
    Type: Application
    Filed: July 3, 2024
    Publication date: May 1, 2025
    Inventors: Yuling LUO, Wei FENG, Adrian GRZYBOWSKI, Yiyuan YIN, Shiping CHEN
  • Publication number: 20250075093
    Abstract: The present disclosure relates to a coating composition comprising polyvinyl fluoride (PVF), an acrylic copolymer comprising amine and/or hydroxyl functional groups, and an isocyanate or melamine crosslinker with groups that are reactive towards amine or hydroxyl groups. Also disclosed herein are dried or cured coatings resulting from the coating composition, substrates coated with such coating compositions, the resulting dried and/or cured coated substrates, and methods of coating such substrates.
    Type: Application
    Filed: August 14, 2024
    Publication date: March 6, 2025
    Inventors: MICHAEL THOMAS DEMKO, DONALD DOUGLAS MAY, KAUSHIK ROY CHOUDHURY, YIYUAN YIN
  • Publication number: 20250032610
    Abstract: Provided are, inter alia, multispecific antigen binding proteins, or antigen-binding fragments thereof, comprising one or more mutations in the VH/VL domains and/or CH1/CL domains, pharmaceutical compositions comprising same, isolated nucleic acids, vectors, and host cells encoding/expressing same, method of making the multispecific antigen binding proteins, computer readable media for evaluating multispecific antigen binding proteins, and libraries.
    Type: Application
    Filed: June 24, 2024
    Publication date: January 30, 2025
    Applicant: Genentech, Inc.
    Inventors: Paul CARTER, Christoph SPIESS, Yiyuan YIN, Jianhui ZHOU, Wendy SANDOVAL, Jacob CORN, Michael DILLON
  • Patent number: 12188929
    Abstract: Disclosed herein are highly sensitive immunoassays that utilize a capture/release mechanism to reduce non-specific binding and achieve detection with attomolar-level sensitivity. Kits that can be used for carrying out these highly sensitive immunoassays are also disclosed herein.
    Type: Grant
    Filed: May 25, 2021
    Date of Patent: January 7, 2025
    Assignee: Alamar Biosciences, Inc.
    Inventors: Yuling Luo, Wei Feng, Adrian Grzybowski, Yiyuan Yin, Shiping Chen
  • Patent number: 12105084
    Abstract: Disclosed herein are highly sensitive immunoassays that utilize a capture/release mechanism to reduce non-specific binding and achieve detection with attomolar-level sensitivity. Kits that can be used for carrying out these highly sensitive immunoassays are also disclosed herein.
    Type: Grant
    Filed: May 25, 2021
    Date of Patent: October 1, 2024
    Assignee: Alamar Biosciences, Inc.
    Inventors: Yuling Luo, Wei Feng, Adrian Grzybowski, Yiyuan Yin, Shiping Chen
  • Patent number: 12053525
    Abstract: Provided are, inter alia, multispecific antigen binding proteins, or antigen-binding fragments thereof, comprising one or more mutations in the VH/VL domains and/or CH1/CL domains, pharmaceutical compositions comprising same, isolated nucleic acids, vectors, and host cells encoding/expressing same, method of making the multispecific antigen binding proteins, computer readable media for evaluating multispecific antigen binding proteins, and libraries.
    Type: Grant
    Filed: August 5, 2021
    Date of Patent: August 6, 2024
    Assignee: Genentech, Inc.
    Inventors: Paul Carter, Christoph Spiess, Yiyuan Yin, Jianhui Zhou, Wendy Sandoval, Jacob Corn, Michael Dillon
  • Publication number: 20230382985
    Abstract: The present disclosure provides binding agents, such as antibodies (including single chain variable fragments), that specifically bind complement component C3, including human C3, compositions comprising same, and methods of their use. The disclosure also provides related polynucleotides and vectors encoding the binding agents and cells comprising same.
    Type: Application
    Filed: August 10, 2023
    Publication date: November 30, 2023
    Inventors: Dana Yen Mei Duey, Zhonghao Liu, Jie Tang, Yan Wang, Yiyuan Yin, Wenwu Zhai, Jared Martin Higbee
  • Patent number: 11767359
    Abstract: The present disclosure provides binding agents, such as antibodies (including single chain variable fragments), that specifically bind complement component C3, including human C3, compositions comprising same, and methods of their use. The disclosure also provides related polynucleotides and vectors encoding the binding agents and cells comprising same.
    Type: Grant
    Filed: August 19, 2021
    Date of Patent: September 26, 2023
    Assignee: NGM Biopharmaceuticals, Inc.
    Inventors: Dana Yen Mei Duey, Zhonghao Liu, Jie Tang, Yan Wang, Yiyuan Yin, Wenwu Zhai, Jared Martin Higbee
  • Patent number: 11566067
    Abstract: The present disclosure provides binding agents, such as antibodies, that specifically bind Angiopoietin-like protein 8 (ANGPTL8), including human ANGPTL8, and methods of their use.
    Type: Grant
    Filed: August 18, 2020
    Date of Patent: January 31, 2023
    Assignee: NGM Biopharmaceuticals, Inc.
    Inventors: Chun Chu, Xunshan Ding, Zhonghao Liu, Yan Wang, Yiyuan Yin, Wenwu Zhai
  • Publication number: 20220409725
    Abstract: Provided are, inter alia, multispecific antigen binding proteins, or antigen-binding fragments thereof, comprising one or more mutations in the VH/VL domains and/or CH1/CL domains, pharmaceutical compositions comprising same, isolated nucleic acids, vectors, and host cells encoding/expressing same, method of making the multispecific antigen binding proteins, computer readable media for evaluating multispecific antigen binding proteins, and libraries.
    Type: Application
    Filed: August 5, 2021
    Publication date: December 29, 2022
    Applicant: Genentech, Inc.
    Inventors: Paul CARTER, Christoph SPIESS, Yiyuan YIN, Jianhui ZHOU, Wendy SANDOVAL, Jacob CORN, Michael DILLON
  • Publication number: 20220390442
    Abstract: Disclosed herein are highly sensitive immunoassays that utilize a capture/release mechanism to reduce non-specific binding and achieve detection with attomolar-level sensitivity. Kits that can be used for carrying out these highly sensitive immunoassays are also disclosed herein.
    Type: Application
    Filed: June 1, 2022
    Publication date: December 8, 2022
    Inventors: Yuling Luo, Wei Feng, Adrian Grzybowski, Yiyuan Yin, Shiping Chen
  • Publication number: 20220119508
    Abstract: The present disclosure provides binding agents, such as antibodies (including single chain variable fragments), that specifically bind complement component C3, including human C3, compositions comprising same, and methods of their use. The disclosure also provides related polynucleotides and vectors encoding the binding agents and cells comprising same.
    Type: Application
    Filed: August 19, 2021
    Publication date: April 21, 2022
    Inventors: Dana Yen Mei Duey, Zhonghao Liu, Jie Tang, Yan Wang, Yiyuan Yin, Wenwu Zhai, Jared Martin Higbee
  • Publication number: 20220056134
    Abstract: Provided are, inter alia, methods of improving pairing of a heavy chain and a light chain of an antibody (such as a bispecific antibody). Also provided are antibodies (e.g., bispecific antibodies) generated using such methods, libraries, and methods of screening such libraries.
    Type: Application
    Filed: November 8, 2021
    Publication date: February 24, 2022
    Applicant: Genentech, Inc.
    Inventors: Kamal Kishore JOSHI, Paul J. Carter, Yiyuan Yin
  • Patent number: 11136381
    Abstract: The present disclosure provides binding agents, such as antibodies (including single chain variable fragments), that specifically bind complement component C3, including human C3, compositions comprising same, and methods of their use. The disclosure also provides related polynucleotides and vectors encoding the binding agents and cells comprising same.
    Type: Grant
    Filed: April 1, 2019
    Date of Patent: October 5, 2021
    Assignee: NGM Biopharmaceuticals, Inc.
    Inventors: Dana Yen Mei Duey, Zhonghao Liu, Jie Tang, Yan Wang, Yiyuan Yin, Wenwu Zhai, Jared Martin Higbee
  • Publication number: 20210285941
    Abstract: Disclosed herein are highly sensitive immunoassays that utilize a capture/release mechanism to reduce non-specific binding and achieve detection with attomolar-level sensitivity. Kits that can be used for carrying out these highly sensitive immunoassays are also disclosed herein.
    Type: Application
    Filed: May 25, 2021
    Publication date: September 16, 2021
    Inventors: Yuling Luo, Wei Feng, Adrian Grzybowski, Yiyuan Yin, Shiping Chen
  • Patent number: 11116840
    Abstract: Provided are, inter alia, multispecific antigen binding proteins, or antigen-binding fragments thereof, comprising one or more mutations in the VH/VL domains and/or CH1/CL domains, pharmaceutical compositions comprising same, isolated nucleic acids, vectors, and host cells encoding/expressing same, method of making the multispecific antigen binding proteins, computer readable media for evaluating multispecific antigen binding proteins, and libraries.
    Type: Grant
    Filed: October 20, 2017
    Date of Patent: September 14, 2021
    Assignee: Genentech, Inc.
    Inventors: Paul Carter, Christoph Spiess, Yiyuan Yin, Jianhui Zhou, Wendy Sandoval, Jacob Corn, Michael Dillon
  • Publication number: 20210278398
    Abstract: Disclosed herein are highly sensitive immunoassays that utilize a capture/release mechanism to reduce non-specific binding and achieve detection with attomolar-level sensitivity. Kits that can be used for carrying out these highly sensitive immunoassays are also disclosed herein.
    Type: Application
    Filed: May 25, 2021
    Publication date: September 9, 2021
    Inventors: Yuling Luo, Wei Feng, Adrian Grzybowski, Yiyuan Yin, Shiping Chen
  • Publication number: 20210095014
    Abstract: The present disclosure provides binding agents, such as antibodies, that specifically bind Angiopoietin-like protein 8 (ANGPTL8), including human ANGPTL8, and methods of their use.
    Type: Application
    Filed: August 18, 2020
    Publication date: April 1, 2021
    Inventors: Chun Chu, Xunshan Ding, Zhonghao Liu, Yan Wang, Yiyuan Yin, Wenwu Zhai