Patents by Inventor Yiyuan Yuan

Yiyuan Yuan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS OF MODULATING SHORT-CHAIN DEHYDROGENASE
    Publication number: 20230322684
    Abstract: Compounds and methods of modulating 15-PGDH activity, modulating tissue prostaglandin levels, treating disease, diseases disorders, or conditions in which it is desired to modulate 15-PGDH activity and/or prostaglandin levels include 15-PGDH inhibitors described herein.
    Type: Application
    Filed: June 9, 2023
    Publication date: October 12, 2023
    Inventors: Sanford Markowitz, Yiyuan Yuan, Yongyou Zhang, Joseph Ready, Bin Hu
  • Compositions and methods of modulating short-chain dehydrogenase
    Patent number: 11718589
    Abstract: Compounds and methods of modulating 15-PGDH activity, modulating tissue prostaglandin levels, treating disease, diseases disorders, or conditions in which it is desired to modulate 15-PGDH activity and/or prostaglandin levels include 15-PGDH inhibitors described herein.
    Type: Grant
    Filed: February 6, 2018
    Date of Patent: August 8, 2023
    Assignees: Case Western Reserve University, Board of Regents of the University of Texas System
    Inventors: Sanford Markowitz, Yiyuan Yuan, Yongyou Zhang, Joseph Ready, Bin Hu
  • INHIBITORS OF SHORT-CHAIN DEHYDROGENASE ACTIVITY FOR TREATING CORONARY DISORDERS
    Publication number: 20230165883
    Abstract: A method of treating preventing, minimizing, and/or reversing congestive heart failure, cardiomyopathy, and/or reduction of cardiac ejection fraction in a subject in need thereof includes administering to the subject a therapeutically effective amount of a 15-PGDH inhibitor.
    Type: Application
    Filed: August 23, 2022
    Publication date: June 1, 2023
    Inventors: Sanford Markowitz, Won Jin Ho, Yiyuan Yuan, Mukesh Jain, Mohamad Sabeh, Joseph Ready, Noelle Williams
  • Inhibitors of short-chain dehydrogenase activity for treating coronary disorders
    Patent number: 11426420
    Abstract: A method of treating preventing, minimizing, and/or reversing congestive heart failure, cardiomyopathy, and/or reduction of cardiac ejection fraction in a subject in need thereof includes administering to the subject a therapeutically effective amount of a 15-PGDH inhibitor.
    Type: Grant
    Filed: April 9, 2018
    Date of Patent: August 30, 2022
    Assignees: CASE WESTERN RESERVE UNIVERSITY, BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Sanford Markowitz, Won Jin Ho, Yiyuan Yuan, Mukesh Jain, Mohamed Sabeh, Joseph Ready, Noelle Williams
  • COMPOSITIONS AND METHODS OF MODULATING SHORT-CHAIN DEHYDROGENASE
    Publication number: 20200095206
    Abstract: Compounds and methods of modulating 15-PGDH activity, modulating tissue prostaglandin levels, treating disease, diseases disorders, or conditions in which it is desired to modulate 15-PGDH activity and/or prostaglandin levels include 15-PGDH inhibitors described herein.
    Type: Application
    Filed: February 6, 2018
    Publication date: March 26, 2020
    Inventors: Sanford Markowitz, Yiyuan Yuan, Yongyou Zhang, Joseph Ready, Bin Hu
  • INHIBITORS OF SHORT-CHAIN DEHYDROGENASE ACTIVITY FOR TREATING CORONARY DISORDERS
    Publication number: 20200030348
    Abstract: A method of treating preventing, minimizing, and/or reversing congestive heart failure, cardiomyopathy, and/or reduction of cardiac ejection fraction in a subject in need thereof includes administering to the subject a therapeutically effective amount of a 15-PGDH inhibitor.
    Type: Application
    Filed: April 9, 2018
    Publication date: January 30, 2020
    Inventors: Sanford Markowitz, Won Jin Ho, Yiyuan Yuan, Mukesh Jain, Mohamed Sabeh, Joseph Ready, Noelle Williams