Abstract: A display adaptation method for an application executed by a terminal includes: displaying a setting interface for setting at least one zone boundary of an interface safe operation zone, the interface safe operation zone being a zone used for displaying a human-computer interaction control responsive to one or more gesture operations in the application; receiving a boundary setting operation triggered on the setting interface; determining positional parameters of zone boundaries of the interface safe operation zone according to the boundary setting operation; and generating, according to the positional parameters, the interface safe operation zone adapted to the terminal.

Abstract: The present application belongs to the field of medicinal chemistry, and relates to crystals of an aniline pyrimidine compound serving as an EGFR inhibitor. Specifically, the present application relates to crystal A, crystal B and crystal C of N-(2-((2-(dimethyl amino)ethyl)(methyl)amino)-4-methoxy-5-(4-(3-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-1-base)pyrimidine-2-base amino)phenyl)acrylamide (formula I) hydrochloride, and also relates to the method for preparing the crystal A, the crystal B and the crystal C, a crystal composition comprising the crystal A, the crystal B, and the crystal C, a pharmaceutical composition comprising the crystal A, the crystal B and the crystal C or the crystal composition thereof, and medical uses thereof. The crystal A, the crystal B and the crystal C in the present application has the advantages of high purity, high crystallization degree, good stability and the like.

Abstract: Compositions that include: from 5 wt-% to 70 wt-% of one or more plant based oils based on the total weight of the composition; from 35 wt-% to 95 wt-% of an aqueous phase based on the total weight of the composition; not greater than 7.5 wt-% of one or more surfactants based on the total weight of the composition; and not greater than 3 wt-% of a viscosity modifier of, wherein the composition has a pH from 4.5 to 9.5, the composition is an oil in water (o/w) emulsion, and the composition is edible. Methods of utilizing disclosed compositions are also included.

Abstract: A dispenser (1) for liquids includes a reservoir (100) defining a volume (V100) for housing a liquid (150); a delivery tube (200) with a first end (201) attached to the reservoir, and a second end (202) distal from the reservoir, the delivery tube including a passage (203) in fluid communication with the volume of the reservoir and extending away from the reservoir; an applicator element (300) including an applicator tip (320) and a base (310) attached to the second end of the delivery tube, the applicator tip having a plurality of fingers (322) extending away from the base to a distal end of the applicator element distal from the delivery tube; and a removable seal (340), wherein removal of the removable seal creates an opening in the passage at a location upstream of the applicator tip and a fluid distribution channel between the fingers.

Abstract: Compositions that are curable to polythioether polymers are provided, comprising: a) a dithiol monomer; b) a diene monomer; c) a radical cleaved photoinitiator; d) a peroxide; and e) an amine; where the peroxide and amine together are a peroxide-amine redox initiator. In some embodiments, the amine is a tertiary amine. In some embodiments, the amine is selected from the group consisting of dihydroxyethyl-p-toluidine, N,N-diisopropylethylamine, and N, N, N?, N?, N?-pentamethyl-diethylenetriamine. In some embodiments, the peroxide is selected from the group consisting of di-tert-butyl peroxide, methyl ethyl ketone peroxide, and benzoyl peroxide.

Abstract: An oral composition is described. The oral composition can include a solvent having water and a cosolvent chosen from lower alkyl alcohols and acetone; a basic copolymer having basic acrylate monomeric units, basic methacrylate monomeric units, or a combination thereof; no less than 0.5 wt-% of an acid buffering or neutralizing agent; and optionally an active agent. The oral composition can include from about 6° to about 15° wt % of water, from about 30° to about 80° wt % of the cosolvent, and from about 25 to about 55° wt-% of the basic copolymer. The basic copolymer can be dissolved in the oral composition, the oral composition is capable of forming a film on a surface when contacted with an aqueous solution; and the wt-% of each component is based on the total weight of the composition.

Abstract: An aqueous oral care fluoride treatment composition, a method of providing fluoride to a patient's tooth surface, and a method of reducing the incidence of dental caries, wherein the composition includes: 0.1 wt-% to 3.0 wt-% of a crosslinked poly acid having carboxylic acid side groups; a pharmaceutically acceptable buffer; 1.0 wt-% to 2.5 wt-% of sodium fluoride; 0.025 wt-% to 1.75 wt-% of a multivalent cation salt; and at least 60 wt-% water; wherein the weight percentages are based on the total weight of the aqueous composition.

Abstract: In one aspect, a composition for decomposing pharmaceutically active agents comprises an oxidizer comprising a permanganate, and an isocyanurate; and an immobilizer. In another aspect, a composition comprises up to 50 wt. % of an oxidizer comprising potassium permanganate and sodium dichloroisocyanurate dehydrate, wherein the wt. % is based on a total weight of the composition.

Abstract: Compositions that are curable to polythioether polymers are provided, comprising: a) a dithiol monomer; b) a diene monomer; c) a radical cleaved photoinitiator; d) a peroxide; and e) an amine; where the peroxide and amine together are a peroxide-amine redox initiator. In some embodiments, the amine is a tertiary amine. In some embodiments, the amine is selected from the group consisting of dihydroxyethyl-p-toluidine, N,N-diisopropylethylamine, and N, N, N?, N?, N?-pentamethyl-diethylenetriamine. In some embodiments, the peroxide is selected from the group consisting of di-tert-butyl peroxide, methyl ethyl ketone peroxide, and benzoyl peroxide. In some embodiments, the composition may additionally comprise a polythiol monomer having three or more thiol groups.

Abstract: An aqueous oral care fluoride treatment composition, a method of providing fluoride to a patient's tooth surface, and a method of reducing the incidence of dental caries, wherein the composition includes: 0.5 wt-% to 4.8 wt-% of a water-soluble cationic N-containing polymer, a pharmaceutically acceptable buffer, 1.0 wt-% to 2.5 wt-% of sodium fluoride; and at least 60 wt-% water, wherein the weight percentages are based on the total weight of the aqueous composition.

Abstract: An aqueous oral care fluoride treatment composition, a method of providing fluoride to a patient's tooth surface, and a method of reducing the incidence of dental caries, wherein the composition includes: 0.1 wt-% to 3.0 wt-% of a crosslinked poly acid having carboxylic acid side groups; a pharmaceutically acceptable buffer; 1.0 wt-% to 2.5 wt-% of sodium fluoride; 0.025 wt-% to 1.75 wt-% of a multivalent cation salt; and at least 60 wt-% water; wherein the weight percentages are based on the total weight of the aqueous composition.

Abstract: A composition for decomposing pharmaceutically active agents, comprises up to 30 wt. % oxidizer; and up to 30 wt. % immobilizer; wherein the wt. % is based on a total weight of the composition.

Abstract: A composition for decomposing pharmaceutically active agents, comprises up to 30 wt. % oxidizer; and up to 30 wt. % immobilizer; wherein the wt. % is based on a total weight of the composition.

Abstract: A system includes a dental appliance having a polymeric shell with a plurality of cavities for receiving one or more teeth; and a biocompatible cosmetic aqueous liquid in the cavities of the polymeric shell of the dental appliance. The aqueous liquid includes a viscosity modifier chosen from a water compatible polymer, a polysaccharide, a silica compound, and mixtures and combinations thereof, a tooth re-mineralizing agent, and water. The aqueous liquid is substantially free of tooth whitening agents and fluoride, and has a refractive index of greater than 1.3 at room temperature.

Abstract: A transparent conductor is provided, including a visible light transparent substrate and metal traces disposed on the substrate, and a layer of a second metal deposited on at least a portion of the metal traces. The transparent conductor further includes a layer of a second metal, which conforms to the surface structure of the metal traces on which it is deposited. Optionally, the transparent conductor also includes a coating layer disposed on a portion of the metal traces and the substrate surface. The coating layer includes a polymer prepared from a polymerizable composition containing at least one ionic liquid monomer. A method of forming a transparent conductor is also provided, including obtaining a visible light transparent substrate having metal traces disposed on the substrate and applying a coating composition on a portion of the metal traces and substrate. The coating composition contains at least one noble metal salt and at least one polymerizable ionic liquid monomer.

Abstract: The present invention relates to a method for synthesizing a compound of 3-(difluoromethyl)-1-methyl-1h-pyrazole-4-carboxylic acid, wherein including the steps of: (A) the diethyl ester compounds represented by the following Formula IV are reacted under the action of amine, alkali and carbonyl reagents to produce the acrylic diester compound represented by the following Formula I, wherein: (B) the above compound represented by the Formula I is reacted with a fluoride reagent, a Lewis acid and a methyl hydrazine to form a pyrazole ring-containing diester compound represented by the Formula II, (C) the heterocyclic-containing diester compound represented by the Formula II is reacted with a base to give 3-(difluoromethyl)-1-methyl-1h-pyrazole-4-carboxylic acid represented by the Formula III.

Abstract: An oral composition is described. The oral composition can include a solvent having water and a cosolvent chosen from lower alkyl alcohols and acetone; a basic copolymer having basic acrylate monomeric units, basic methacrylate monomeric units, or a combination thereof; no less than 0.5 wt-% of an acid buffering or neutralizing agent; and optionally an active agent. The oral composition can include from about 6° to about 15° wt % of water, from about 30° to about 80° wt % of the cosolvent, and from about 25 to about 55° wt-% of the basic copolymer. The basic copolymer can be dissolved in the oral composition, the oral composition is capable of forming a film on a surface when contacted with an aqueous solution; and the wt-% of each component is based on the total weight of the composition.

Abstract: Methods and devices for extracting feature descriptors for a video, the video having a sequence of pictures. The method includes identifying a first key picture and a second key picture later in the sequence than the first key picture; extracting a first set of feature descriptors from the first key picture and a second set of feature descriptors from the second key picture; identifying a set of pairs of feature descriptors, where each pair includes one descriptor from the first set and one descriptor from the second set; generating motion information describing the motion field between the first key picture and the second key picture; and filtering the set of pairs of feature descriptors based on correlation with the motion information to produce and output a subset of persistent descriptors.

Abstract: Provided is a method for preparing an intermediate of 6-arylaminopyridonecarboxamide compound as an MEK inhibitor, comprising preparing a compound of formula (III) as an intermediate of 6-arylaminopyridonecarboxamide compound using a compound of formula V as a raw material.

Abstract: Compositions that include from 0.1 wt-% to 8 wt-% of one or more compounds of formula (I) based on the total weight of the composition HOCH2—(CHOH)n—CH2NR1R2??(I) wherein R1 and R2 are independently selected from the group consisting of a hydrogen atom, an alkyl group, C(O)R3, and SO2R4; with R3 and R4 being independently selected from the group consisting of an alkyl group, an aryl group, and an aralkyl group; wherein n is an integer from about 2 to about 5; from 5 wt-% to 95 wt-% of one or more plant based oils based on the total weight of the composition; from 5 wt-% to 80 wt-% water based on the total weight of the composition and from 0.01 wt-% to 1 wt-% of one or more nonionic aromatic phenolic preservatives based on the total weight of the composition wherein the composition has a pH from 4.5 to 9.5, the composition is an emulsion, and the composition is edible.