Patents by Inventor Yizhou Zhao

Yizhou Zhao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds for the Degradation of EGFR Kinase
    Publication number: 20240425523
    Abstract: Disclosed herein are novel bifunctional compounds formed by conjugating EGFR inhibitor moieties with E3 ligase ligand moieties, methods of preparation, and uses thereof.
    Type: Application
    Filed: May 30, 2024
    Publication date: December 26, 2024
    Inventors: Huaqing Liu, Bailin Lei, Yizhou Zhao, Xinzhu Qi, Guanjun Liu, Zhiwei Wang
  • DEGRADATION OF (EGFR) BY CONJUGATION OF EGFR INHIBITORS WITH E3 LIGASE LIGAND AND METHODS OF USE
    Publication number: 20240368203
    Abstract: Disclosed herein are novel bifunctional compounds formed by conjugating EGFR inhibitor moieties with E3 ligase Ligand moieties, which function to recruit targeted proteins to E3 ubiquitin ligase for degradation, and methods of preparation and uses thereof.
    Type: Application
    Filed: July 12, 2024
    Publication date: November 7, 2024
    Applicant: BeiGene, Ltd.
    Inventors: Bailin LEI, Huaqing LIU, Songzhe HAN, Yizhou ZHAO, Zhiwei WANG
  • Compounds for the Degradation of EGFR Kinase
    Publication number: 20240342292
    Abstract: Disclosed herein are novel bifunctional compounds formed by conjugating EGFR inhibitor moieties with E3 ligase Ligand moieties, which function to recruit targeted proteins to E3 ubiquitin ligase for degradation, and methods of preparation and uses thereof.
    Type: Application
    Filed: May 29, 2024
    Publication date: October 17, 2024
    Applicant: BeiGene Switzerland GmbH
    Inventors: Bailin Lei, Huaqing Liu, Songzhe Han, Yizhou Zhao, Zhiwei Wang, Guanjun Liu, Haijun Liu
  • ADHESIVE APPLICATOR INCLUDING NOVEL APPLICATOR TIP
    Publication number: 20230233197
    Abstract: An applicator is provided for a flowable media, particularly an adhesive contained in a container and the applicator includes an elongate body member having an internal cavity that holds the container. The cavity has a distal end with a breaking means that is actuated by an axial force. Various embodiments of the actuator are shown to apply the force, including a wire cracker and a molded integral handle member with a lever linkage that bears against a ram which holds the ampoule and having a spring arm that rides within the cavity to oppose a pivoting force on the handle. These embodiments also enable single handed use.
    Type: Application
    Filed: June 16, 2021
    Publication date: July 27, 2023
    Inventors: Jack GOODMAN, David KAY, Ananth MURTHY, Darren OBRIGKEIT, Gary PENNINGTON, Yizhou ZHAO, Joseph SPALDING, Jonathan MORGAN, Michael TRACZ, PAUL WYMAN
  • Augmented reality display device, and apparatus comprising same
    Patent number: 11665319
    Abstract: An augmented reality display device, includes: a display unit including a thermal camera configured to capture image frames, an image projector, and a display screen; a processing unit including processing structure in communication with the thermal camera and the image projector, the processing structure being configured to process the captured image frames and output processed image frames to the image projector, and a battery; and a strap connecting the display unit and the processing unit.
    Type: Grant
    Filed: January 15, 2020
    Date of Patent: May 30, 2023
    Inventors: Enzo (Mingpo) Jia, Yizhou Zhao, Anzhou Xing, Qibo Kong, Yuanming Cao, Alex Shortt
  • AUGMENTED REALITY DISPLAY DEVICE, AND APPARATUS COMPRISING SAME
    Publication number: 20220094883
    Abstract: An augmented reality display device, includes: a display unit including a thermal camera configured to capture image frames, an image projector, and a display screen; a processing unit including processing structure in communication with the thermal camera and the image projector, the processing structure being configured to process the captured image frames and output processed image frames to the image projector, and a battery; and a strap connecting the display unit and the processing unit.
    Type: Application
    Filed: January 15, 2020
    Publication date: March 24, 2022
    Inventors: Enzo (Mingpo) Jia, Yizhou Zhao, Anzhou Xing, Qibo Kong, Yuanming Cao, Alex Shortt