Patents by Inventor Yizhu CHEN

Yizhu CHEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12144491
    Abstract: A spectrally encoded fluorescence imaging system includes a multi-wavelength excitation light source emitting excitation light for illuminating a sample, optical components for introducing spectral encoding to focus different wavelengths of the excitation light at different positions in the sample to generate fluorescence at different, spatial positions, and band-shifting florescence imaging probes exhibiting excitation-dependent emission band, causing the fluorescence generated at different spatial positions to exhibit different band shifts, such that image information is encoded in the band-shifted fluorescence spectrums for parallel detection by a spectrometer or arrayed detectors operable to resolve different wavelengths.
    Type: Grant
    Filed: July 30, 2019
    Date of Patent: November 19, 2024
    Assignee: The Penn State Research Foundation
    Inventors: Zhiwen Liu, Jian Yang, Yizhu Chen, Dingbowen Wang
  • Publication number: 20210228066
    Abstract: A spectrally encoded fluorescence imaging system includes a multi-wavelength excitation light source emitting excitation light for illuminating a sample, optical components for introducing spectral encoding to focus different wavelengths of the excitation light at different positions in the sample to generate fluorescence at different, spatial positions, and band-shifting florescence imaging probes exhibiting excitation-dependent emission band, causing the fluorescence generated at different spatial positions to exhibit different band shifts, such that image information is encoded in the band-shifted fluorescence spectrums for parallel detection by a spectrometer or arrayed detectors operable to resolve different wavelengths.
    Type: Application
    Filed: July 30, 2019
    Publication date: July 29, 2021
    Inventors: Zhiwen Liu, Jian Yang, Yizhu Chen, Dingbowen Wang
  • Patent number: 9642832
    Abstract: A medicament for inhibiting platelet aggregation, comprising atractylenolide compound or its derivatives, wherein the said atractylenolide compound has the following structural formula shown in formula (I), wherein R1 represents H or C1-C10 linear or branched alkyl, R2 represents H or C1-C10 linear or branched alkyl, and R3 represents H or hydroxyl. Use of atractylenolide compound shown in formula (I) or its derivatives in the manufacture of a medicament for inhibiting platelet aggregation. The medicament for inhibiting platelet aggregation of the present application has good efficacy without toxic-and-side effect, lower tendency of tolerance, convenient to take and applicable for preventing or treating diseases caused by high platelet aggregation rate.
    Type: Grant
    Filed: April 16, 2015
    Date of Patent: May 9, 2017
    Assignee: NO. 9 PEOPLE HOSPITAL AFFILIATED TO SHANGHAI JIAOTOG UNIVERSITY SCHOOL OF MEDICINE
    Inventors: Junfeng Zhang, Yizhu Chen
  • Publication number: 20160324825
    Abstract: A medicament for inhibiting platelet aggregation, comprising atractylenolide compound or its derivatives, wherein the said atractylenolide compound has the following structural formula shown in formula (I), wherein R1 represents H or C1-C10 linear or branched alkyl, R2 represents H or C1-C10 linear or branched alkyl, and R3 represents H or hydroxyl. Use of atractylenolide compound shown in formula (I) or its derivatives in the manufacture of a medicament for inhibiting platelet aggregation. The medicament for inhibiting platelet aggregation of the present application has good efficacy without toxic-and-side effect, lower tendency of tolerance, convenient to take and applicable for preventing or treating diseases caused by high platelet aggregation rate.
    Type: Application
    Filed: April 16, 2015
    Publication date: November 10, 2016
    Inventors: Junfeng ZHANG, Yizhu CHEN