Abstract: A garment for neuro-musculo-skeletal assistance comprising a body (2) of the garment provided with elasticity and intended to be worn by a user to adhere to a portion of the user's body and an elastic and continuous framework (5) on the body of the garment and comprising a plurality of anchoring portions (10) and a plurality of active portions (20; 30; 40; 50), each intended to coincide with respective sectors of the user's body, where the framework is structured so that, when the garment is worn by the user and the latter carries out a motor activity, the active portions deform themselves following the deformation of the respective sectors of the user's body and the anchoring portions remain substantially unchanged.