Patents by Inventor Yochanan Uri
Yochanan Uri has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11480565Abstract: An instrument for detecting signal from a biological sample includes a pipettor module configured to hold a plurality of pipettes in respective pipette positions, to hold liquid in one or more pipette tips, and to pipette liquid in and out of the one or more pipette tips. Each of the one or more pipette tips has a pipette tip point. The instrument further includes one or more magnets positioned such that each of the one or more pipette tips is adjacent one of the one or more magnets.Type: GrantFiled: June 12, 2020Date of Patent: October 25, 2022Assignee: Bio-Rad Laboratories, Inc.Inventors: Shai Nimri, Yochanan Uri, Boaz Ran
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Publication number: 20210389305Abstract: An instrument for detecting signal from a biological sample includes a pipettor module configured to hold a plurality of pipettes in respective pipette positions, to hold liquid in one or more pipette tips, and to pipette liquid in and out of the one or more pipette tips. Each of the one or more pipette tips has a pipette tip point. The instrument further includes one or more magnets positioned such that each of the one or more pipette tips is adjacent one of the one or more magnets.Type: ApplicationFiled: June 12, 2020Publication date: December 16, 2021Inventors: Shai NIMRI, Yochanan URI, Boaz RAN
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Publication number: 20200360924Abstract: The present disclosure is notably directed to a microfluidic probe head (202), or MFP head, comprising a processing surface (204) having liquid injection and liquid aspiration apertures, as well as projections (205) extending from the processing surface (204). The arrangement of injection and aspiration apertures provides for a hydrodynamic flow confinement within a processing region that is formed between the processing surface (204) and a substrate (104) or sample surface (for example, the bottom of a microtiter plate sample well (102)), typically located beneath the processing surface (204). The disclosure is further directed to related microfluidic probe devices, and methods of operation of such an MFP head, notably to deposit cells on a surface.Type: ApplicationFiled: August 4, 2020Publication date: November 19, 2020Inventors: Yochanan Uri, Itay Barak, Robert Lovchik, David P. Taylor, Marcel Buerge, Govind V. Kaigala
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Patent number: 10359397Abstract: Horizontal gel electrophoresis devices and methods of extracting a gel from a gel housing are provided. The devices allow for extraction of gels without having to open the housing comprising the gel. The devices include gel cassettes that simplify the automation of gel electrophoresis and electroblotting of proteins. Also provided are devices that allow for horizontal gel electrophoresis without the need to from a liquid seal between the buffer reservoir and the gel housing. Also described are methods for extracting a gel from a housing without opening the housing.Type: GrantFiled: December 14, 2015Date of Patent: July 23, 2019Assignee: Bio-Rad Laboratories, Inc.Inventors: Yochanan Uri, Uri Issman, Igor Kochetkov, Itay Barak, Shai Aharon, Shai Nimri
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Publication number: 20180372680Abstract: Gel cassette opening devices and methods for opening gel cassettes are provided.Type: ApplicationFiled: June 20, 2018Publication date: December 27, 2018Inventors: Yochanan URI, Igor KOCHETKOV, Uri ISSMAN, Shai AHARON
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Publication number: 20180299475Abstract: Fraction collector dispensers and methods of using such dispensers are provided. In one embodiment, the dispenser includes an inlet for receiving liquid from a liquid source, wherein the inlet is in fluid communication with an outlet from which liquid is dispensed into a receptacle; and a reservoir in fluid communication with a flow path between the inlet and outlet, wherein the reservoir comprises trapped air therein and is configured to receive liquid during movement of the dispenser between receptacles or during movement of receptacles between dispense positions, wherein the dispenser is moveable between a first receptacle and a second receptacle or the receptacles are moveable between dispense positions.Type: ApplicationFiled: April 2, 2018Publication date: October 18, 2018Inventors: Yochanan Uri, Igor KOCHETKOV, Shai AHARON, Itay BARAK, Uri ISSMAN
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Patent number: 9933565Abstract: Devices, systems, methods, and kits for contact imaging are provided. A contact imaging device includes an imaging sensor, a fixed fiber faceplate mechanically coupled to the imaging sensor, and an optical filtering layer mechanically coupled to the fixed fiber faceplate. The optical filtering layer can include an interference filter, an absorptive filter, and/or a removable fiber faceplate. The contact imaging device can be used to image fluorescent samples by filtering out excitation light on the basis of wavelength and/or angle of incidence.Type: GrantFiled: July 15, 2016Date of Patent: April 3, 2018Assignee: Bio-Rad Laboratories, Inc.Inventors: Steve Swihart, Evan Thrush, Yochanan Uri, Boaz Ran, Itay Barak, Kevin McDonald
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Patent number: 9829434Abstract: A tip for use in an optical detection system to analyze an analyte in a fluid sample drawn into the tip, using light reflected from a detection surface inside the tip that the analyte binds to, comprising a first detection surface and a second detection surface located in a same flow path with no controllable valve separating them, wherein the first and second detection surfaces have different surface chemistries.Type: GrantFiled: March 15, 2016Date of Patent: November 28, 2017Assignee: Bio-Rad Laboratories Inc.Inventors: Yochanan Uri, Boaz Ran, Ariel G. Notcovich, Shay Nimri
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Patent number: 9794454Abstract: Provided herein are imaging cassettes for detecting a luminescent and/or radioactive signals. Such cassettes are useful in common biological assays, e.g., immunoassays, nucleotide detection assays, and other affinity assays.Type: GrantFiled: July 1, 2015Date of Patent: October 17, 2017Assignee: Bio-Rad Laboratories, Inc.Inventors: Yochanan Uri, Boaz Ran, Itay Barak, Steven Swihart, Evan Thrush
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Publication number: 20170016829Abstract: Devices, systems, methods, and kits for contact imaging are provided. A contact imaging device includes an imaging sensor, a fixed fiber faceplate mechanically coupled to the imaging sensor, and an optical filtering layer mechanically coupled to the fixed fiber faceplate. The optical filtering layer can include an interference filter, an absorptive filter, and/or a removable fiber faceplate. The contact imaging device can be used to image fluorescent samples by filtering out excitation light on the basis of wavelength and/or angle of incidence.Type: ApplicationFiled: July 15, 2016Publication date: January 19, 2017Inventors: Steve SWIHART, Evan THRUSH, Yochanan URI, Boaz RAN, Itay BARAK, Kevin MCDONAL
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Publication number: 20160299099Abstract: Horizontal gel electrophoresis devices and methods of extracting a gel from a gel housing are provided. The devices allow for extraction of gels without having to open the housing comprising the gel. The devices include gel cassettes that simplify the automation of gel electrophoresis and electroblotting of proteins. Also provided are devices that allow for horizontal gel electrophoresis without the need to from a liquid seal between the buffer reservoir and the gel housing. Also described are methods for extracting a gel from a housing without opening the housing.Type: ApplicationFiled: December 14, 2015Publication date: October 13, 2016Inventors: Yochanan Uri, Uri Issman, Igor Kochetkov, Itay Barak, Shai Aharon, Shai Nimri
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Publication number: 20160299070Abstract: A tip for use in an optical detection system to analyze an analyte in a fluid sample drawn into the tip, using light reflected from a detection surface inside the tip that the analyte binds to, comprising a first detection surface and a second detection surface located in a same flow path with no controllable valve separating them, wherein the first and second detection surfaces have different surface chemistries.Type: ApplicationFiled: March 15, 2016Publication date: October 13, 2016Applicant: Bio-Rad Laboratories Inc.Inventors: Yochanan URI, Boaz RAN, Ariel G. NOTCOVICH, Shay NIMRI
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Patent number: 9354179Abstract: A tip for use in an optical detection system to analyze an analyte in a fluid sample drawn into the tip, using light reflected from a detection surface inside the tip that the analyte binds to, comprising a first detection surface and a second detection surface located in a same flow path with no controllable valve separating them, wherein the first and second detection surfaces have different surface chemistries.Type: GrantFiled: June 6, 2013Date of Patent: May 31, 2016Assignee: Bio-Rad Laboratories Inc.Inventors: Yochanan Uri, Boaz Ran, Ariel G. Notcovich, Shay Nimri
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Publication number: 20160006910Abstract: Provided herein are imaging cassettes for detecting a luminescent and/or radioactive signals. Such cassettes are useful in common biological assays, e.g., immunoassays, nucleotide detection assays, and other affinity assays.Type: ApplicationFiled: July 1, 2015Publication date: January 7, 2016Inventors: Yochanan Uri, Boaz Ran, Itay Barak, Steven Swihart, Evan Thrush
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Patent number: 8743367Abstract: An SPR or other optical resonance based analysis system in which, light is provided at multiple angles to a specimen and then the light modified by the specimen is processed to select only some of the light. Optionally, the processing selects light at a particular incidence angle. Optionally, the detection is by imaging of the light on a 2D imager array.Type: GrantFiled: May 21, 2008Date of Patent: June 3, 2014Assignee: Bio-Rad Laboratories Inc.Inventors: Boaz Ran, Tal Rosenzweig, Ariel G. Notcovich, Ariel Shemesh, Yochanan Uri, Michael Kanevsky, James W. Hillendahl, Barak Abraham Liraz
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Publication number: 20130330230Abstract: A tip for use in an optical detection system to analyze an analyte in a fluid sample drawn into the tip, using light reflected from a detection surface inside the tip that the analyte binds to, comprising a first detection surface and a second detection surface located in a same flow path with no controllable valve separating them, wherein the first and second detection surfaces have different surface chemistries.Type: ApplicationFiled: June 6, 2013Publication date: December 12, 2013Inventors: Yochanan URI, Boaz Ran, Ariel G. Notcovich, Shay Nimri
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Publication number: 20100220330Abstract: An SPR or other optical resonance based analysis system in which, light is provided at multiple angles to a specimen and then the light modified by the specimen is processed to select only some of the light. Optionally, the processing selects light at a particular incidence angle. Optionally, the detection is by imaging of the light on a 2D imager array.Type: ApplicationFiled: May 21, 2008Publication date: September 2, 2010Applicant: Bio-Rad Laboratories Inc.Inventors: Boaz Ran, Tal Rosenzweig, Ariel G. Notcovich, Ariel Shemesh, Yochanan Uri, Michael Kanevsky, James W. Hillendahl, Barak Abraham Liraz