Patents by Inventor Yogen Saunthararajah

Yogen Saunthararajah has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS COMPRISING DECITABINE AND TETRAHYDROURIDINE AND USES THEREOF
    Publication number: 20120225836
    Abstract: Embodiments of compositions and methods for the treatment of blood disorders and malignancies in a subject are described herein. In one embodiment, a composition for the treatment of a blood disorder or a malignancy in a subject comprises decitabine, tetrahydrouridine, and an excipient. In another embodiment, a method for the treatment of a blood disorder or a malignancy in a subject comprises the oral administration of a composition comprising decitabine and tetrahydrouridine. In some examples, the composition may be administered 1-3 times weekly.
    Type: Application
    Filed: March 7, 2012
    Publication date: September 6, 2012
    Applicant: The Board of Trustees of the University of Illinois
    Inventors: Joseph Desimone, Yogen Saunthararajah
  • COMPOSITIONS COMPRISING DECITABINE AND TETRAHYDROURIDINE AND USES THEREOF
    Publication number: 20110287092
    Abstract: Compositions comprising decitabine and tetrahydrouridine for the treatment of blood disorders and hematological and solid malignancies are described.
    Type: Application
    Filed: December 21, 2009
    Publication date: November 24, 2011
    Applicant: The Board of Trustees of the University of Illinois
    Inventors: Joseph Desimone, Yogen Saunthararajah
  • Methods for in vitro expansion of hematopoietic stem cells
    Patent number: 7927785
    Abstract: The invention relates to methods of obtaining compositions for generating multipotent hematopoietic stem progenitor cells comprising expansion of hematopoietic stem cells in the presence of HDACI and IDM. Methods of obtaining compositions enriched in hematopoietic megakaryocyte progenitor cells are also provided. Compositions enriched for stem cells and populations of cells obtained therefrom are also provided by the invention.
    Type: Grant
    Filed: May 12, 2005
    Date of Patent: April 19, 2011
    Assignee: The Board of Trustees of the University of Illinois
    Inventors: Mohammed Milhem, Nadim Mahmud, Donald Lavelle, Yogen Saunthararajah, Joseph De Simone, Ronald Hoffman
  • Methods for in vitro expansion of hematopoietic stem cells
    Publication number: 20050276793
    Abstract: The invention relates to methods of obtaining compositions for generating multipotent hematopoietic stem progenitor cells comprising expansion of hematopoietic stem cells in the presence of HDACI and IDM. Methods of obtaining compositions enriched in hematopoietic megakaryocyte progenitor cells are also provided. Compositions enriched for stem cells and populations of cells obtained therefrom are also provided by the invention.
    Type: Application
    Filed: May 12, 2005
    Publication date: December 15, 2005
    Applicant: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
    Inventors: Mohammed Milhem, Nadim Mahmud, Donald Lavelle, Yogen Saunthararajah, Joseph De Simone, Ronald Hoffman