Patents by Inventor Yohannes Tesfaigzi

Yohannes Tesfaigzi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Metalloproteinase gene polymorphism in copd
    Publication number: 20070037156
    Abstract: A method for genetic testing relating to chronic obstructive pulmonary disease (COPD), including testing for a single nucleotide polymorphism within the metal loproteinase-9 gene, an exon 6, codon 279 Gln/Arg polymorphism, where in presence of the variant polymorphism, particularly homozygous presence, is predictive of susceptibility to COPD. Further provided are methods of selecting patients for specific therapies and methods of drug development and discovery for treatment and prevention of COPD.
    Type: Application
    Filed: August 11, 2004
    Publication date: February 15, 2007
    Applicant: Lovelace Respiratory Research Institute
    Inventors: Yohannes Tesfaigzi, Steven Belinsky
  • Modulating inflammation with cytochrome P-450 activators and inhibitors
    Patent number: 6121299
    Abstract: This invention relates to methods of modulating inflammation in mammals. Inflammation is modulated by regulating the cytochrome P-450 pathway. Inflammation is reduced by treating the subject with substances, such as bezafibrate and clofibrate, which induce the P-450 pathway. Inflammation is promoted by treating the subject with substances, such as proadifen, econazole, and clotrimazole, which inhibit the cytochrome P-450 pathway.
    Type: Grant
    Filed: March 30, 1999
    Date of Patent: September 19, 2000
    Assignee: Lovelace Respiratory Research Institute
    Inventors: Wieslaw Kozak, Matthew J. Kluger, Yohannes Tesfaigzi