Patents by Inventor Yohannes Tsegai Ghebremariam

Yohannes Tsegai Ghebremariam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isolated Recombinant Vaccinia Virus Complement Control Protein (Hrvcp) Polypeptide
    Publication number: 20080318858
    Abstract: An isolated recombinant vaccinia virus complement control protein (hrVCP) polypeptide comprises a modified amino acid sequence comprising one or more amino acid substitutions to an amino acid sequence as set forth in SEQ ID NO: 2. The hrVCP polypeptide exhibits a complement activation regulatory activity greater than a complement activation regulatory activity of a polypeptide comprising the amino acid sequence as set forth in SEQ ID NO: 2. The one or more amino acid substitutions are selected from the group consisting of H98Y, E102K, E108K, E120K, and combinations thereof.
    Type: Application
    Filed: June 15, 2006
    Publication date: December 25, 2008
    Inventors: Girish J. Kotwal, Yohannes Tsegai Ghebremariam