Abstract: The present invention relates to a distinct B cell subset, B10 cells, that regulate T cell mediated inflammatory responses through the secretion of interleukin-10 (IL-10). The invention also relates to the use of B10 cells in the manipulation of immune and inflammatory responses, and in the treatment of disease. Therapeutic approaches involving adoptive transfer of B10 cells, or expansion of their endogenous levels for controlling autoimmune or inflammatory diseases and conditions are described. Ablation of B10 cells, or inhibition of their IL-10 production can be used to upregulate immunodeficient conditions, ameliorate infectious diseases and/or to treat tumors/cancer. Diagnostic applications are also encompassed.

Abstract: Provided is an object detecting device that does not require an operator to perform a complicated operation onsite and that allows the number of components to be reduced while a detection range can be set. Provided are: at least two sensor units configured to receive detection rays from different detection areas, the different detection areas being arranged in an up-down direction and having center lines extending in different diagonally downward directions; and an object detection determination section configured to detect an object in a detection range based on one or more of at least two detection signals corresponding to amounts of detection rays received by the at least two sensor units, respectively, the detection range being determined by setting a reference for the at least two detection signals.

Abstract: The present invention relates to a distinct B cell subset, B10 cells, that regulate T cell mediated inflammatory responses through the secretion of interleukin-10 (IL-10). The invention also relates to the use of B10 cells in the manipulation of immune and inflammatory responses, and in the treatment of disease. Therapeutic approaches involving adoptive transfer of B10 cells, or expansion of their endogenous levels for controlling autoimmune or inflammatory diseases and conditions are described. Ablation of B10 cells, or inhibition of their IL-10 production can be used to upregulate immunodeficient conditions, ameliorate infectious diseases and/or to treat tumors/cancer. Diagnostic applications are also encompassed.

Abstract: The present invention relates to a distinct B cell subset, B10 cells, that regulate T cell mediated inflammatory responses through the secretion of interleukin-10 (IL-10). The invention also relates to the use of B10 cells in the manipulation of immune and inflammatory responses, and in the treatment of disease. Therapeutic approaches involving adoptive transfer of B10 cells, or expansion of their endogenous levels for controlling autoimmune or inflammatory diseases and conditions are described. Ablation of B10 cells, or inhibition of their IL-10 production can be used to upregulate immunodeficient conditions, ameliorate infectious diseases and/or to treat tumors/cancer. Diagnostic applications are also encompassed.

Abstract: There is provided an automatic door sensor device (1) capable of preventing a door (3) which is transitioning from an open position to a closed position from being erroneously detected as an object by temporarily changing a detection area (A, C2, C3). The automatic door sensor device (1) includes a doorway area sensor (7a) that detects the presence of an object in a doorway area (B) which includes at least a portion of an area defined by the path of a door (3), detectors (6, 7b) that detect the presence and/or the movement of an object in changeable detection areas (A, C2, C3), and a detection area changer (31) that changes the detection areas (A, C2, C3) when it is determined, by using the doorway area sensor (7a), that the door (3) is transitioning from an open position to a closed position.

Abstract: There is provided an automatic door sensor device (1) capable of preventing a door (3) which is transitioning from an open position to a closed position from being erroneously detected as an object by temporarily changing a detection area (A, C2, C3). The automatic door sensor device (1) includes a doorway area sensor (7a) that detects the presence of an object in a doorway area (B) which includes at least a portion of an area defined by the path of a door (3), detectors (6, 7b) that detect the presence and/or the movement of an object in changeable detection areas (A, C2, C3), and a detection area changer (31) that changes the detection areas (A, C2, C3) when it is determined, by using the doorway area sensor (7a), that the door (3) is transitioning from an open position to a closed position.

Abstract: An automatic door sensor includes: at least one sensor module unit (sensor module 11) configured to detect optically an object or a human body and to output, according to the detection results, a signal to a door controller for controlling an automatic door to open/close; an accommodation unit (profile 12) capable of accommodating the at least one sensor module unit; a cover member (front cover 13) that is transmissive to light for use for the detection performed by the sensor module unit and configured to cover the accommodation unit in which the sensor module unit is accommodated; and a functionality expansion module (LED module 14) either side of which can be joined to the cover member and that is configured to expand functionalities of the automatic door sensor by performing communication with the sensor module unit.

Abstract: An automatic door sensor includes: at least one sensor module unit (sensor module 11) configured to detect optically an object or a human body and to output, according to the detection results, a signal to a door controller for controlling an automatic door to open/close; an accommodation unit (profile 12) capable of accommodating the at least one sensor module unit; a cover member (front cover 13) that is transmissive to light for use for the detection performed by the sensor module unit and configured to cover the accommodation unit in which the sensor module unit is accommodated; and a functionality expansion module (LED module 14) either side of which can be joined to the cover member and that is configured to expand functionalities of the automatic door sensor by performing communication with the sensor module unit.

Abstract: The present invention relates to a distinct B cell subset, B10 cells, that regulate T cell mediated inflammatory responses through the secretion of interleukin-10 (IL-10). The invention also relates to the use of B10 cells in the manipulation of immune and inflammatory responses, and in the treatment of disease. Therapeutic approaches involving adoptive transfer of B10 cells, or expansion of their endogenous levels for controlling autoimmune or inflammatory diseases and conditions are described. Ablation of B10 cells, or inhibition of their IL-10 production can be used to upregulate immunodeficient conditions, ameliorate infectious diseases and/or to treat tumors/cancer. Diagnostic applications are also encompassed.