Abstract: [Problem] To provide a composition and a cell sheet which are highly effective for inhibiting fibrosis, or cells having fibrosis-inhibiting activity, which are useful in regenerative medicine. [Solution] A medium containing IC-2 or a related compound is inoculated with mesenchymal stem cells or bone marrow mononuclear cells, and the cells are cultured for a prescribed period of time while the IC-2 or related compound is maintained at a constant concentration, thereby allowing a composition and a cell sheet which are highly effective for inhibiting fibrosis, or cultured cells having fibrosis-inhibiting activity, to be obtained.

Abstract: [Problem to be solved by the invention] To provide a cell sheet for increasing fibrosis inhibitory action, said cell sheet comprising bone marrow mononuclear cells, and a production method thereof. [Solution] A cell sheet comprising bone marrow mononuclear cells, said cell sheet being obtained by forming bone marrow mononuclear cells from a bone marrow mononuclear cell suspension into a sheet, and then shrinking and suspension culturing the result.

Abstract: There is proposed a model update device and method, and a process control system, which are capable of significantly reducing the labor, time, and monetary cost required for model update and are also easily applicable to a plant in which the existing model predictive control is introduced, without causing a loss of operating profit. By converting a data format of operation data of a target process into a delay coordinate format and solving a regression problem including a regularization term for the operation data converted into the delay coordinate format, an update model reflecting secular change information of the target process is generated, and the model is replaced with the generated update model to be updated.

Abstract: A data generation device generates a data set and includes: a perturbation generation unit that generates a perturbation set for deforming each element based on at least one of an input of each element of a training data set and information on the training data set; a pseudo data synthesis unit that generates a new pseudo data set different from the training data set from the training data set and the perturbation set; an evaluation unit that calculates a distributional distance of the training data set and the pseudo data set or an estimated amount of the distributional distance and a magnitude of perturbation of the pseudo data with respect to the training data obtained from the perturbation set; and a parameter update unit that updates a parameter used by the perturbation generation unit to generate the perturbation set so that the distributional distance of the training data set and the pseudo data set is close to each other and the magnitude or expected value of the perturbation becomes a predetermined t

Abstract: [Problem] To provide a composition and a cell sheet which are highly effective for inhibiting fibrosis, or cells having fibrosis-inhibiting activity, which are useful in regenerative medicine. [Solution] A medium containing IC-2 or a related compound is inoculated with mesenchymal stem cells or bone marrow mononuclear cells, and the cells are cultured for a prescribed period of time while the IC-2 or related compound is maintained at a constant concentration, thereby allowing a composition and a cell sheet which are highly effective for inhibiting fibrosis, or cultured cells having fibrosis-inhibiting activity, to be obtained.

Abstract: [Problem to be solved by the invention] To provide a cell sheet for increasing fibrosis inhibitory action, said cell sheet comprising bone marrow mononuclear cells, and a production method thereof. [Solution] A cell sheet comprising bone marrow mononuclear cells, said cell sheet being obtained by forming bone marrow mononuclear cells from a bone marrow mononuclear cell suspension into a sheet, and then shrinking and suspension culturing the result.

Abstract: A small and low-price rotating electric machine has a structure where a magnet end surface and a metal tube end are not in contact with each other. The rotating electric machine has a cylindrical stator core, a rotor having a shaft provided on the inner circumferential side of the stator core, a yoke fixed to the shaft, at least one ferrite magnet provided on the outer circumferential surface of the yoke, and a protective cover provided on the outer circumference of the ferrite magnet. The ferrite magnet end surface is projected with respect to an end surface of the yoke, and has a step portion to form a gap between the end surface of the ferrite magnet and a bottom surface of the protective cover.

Abstract: A small and low-price rotating electric machine has a structure where a magnet end surface and a metal tube end are not in contact with each other. The rotating electric machine has a cylindrical stator core, a rotor having a shaft provided on the inner circumferential side of the stator core, a yoke fixed to the shaft, at least one ferrite magnet provided on the outer circumferential surface of the yoke, and a protective cover provided on the outer circumference of the ferrite magnet. The ferrite magnet end surface is projected with respect to an end surface of the yoke, and has a step portion to form a gap between the end surface of the ferrite magnet and a bottom surface of the protective cover.