Abstract: The present invention provides a cationic lipid which can be utilized for nucleic acid delivery into the cytoplasm. The cationic lipid of the present invention is, for example, a compound represented by the following Formula (1) or a pharmaceutically acceptable salt thereof.

Abstract: A compound represented by formula (4): can be produced by adding a heterogeneous transition metal catalyst to a solution containing a compound represented by formula (3): obtained by performing a nitration reaction by adding a nitrating agent to a solution containing a compound represented by formula (2): obtained by oxidizing a compound represented by formula (1): with hydrogen peroxide in the presence of sodium tungstate and a saturated C8 carboxylic acid, then adding water to the resultant mixture, and separating the resultant solution.

Abstract: The present invention provides a cationic lipid which can be used for nucleic acid delivery to a cytoplasm and which is possible to solve the problem of physical stability of a lipid complex. This cationic lipid is a compound represented by the general formula (3) or a pharmaceutically acceptable salt thereof: wherein, L is an alkyl having 7-12 carbon atoms or an alkenyl having 7-12 carbon atoms, R is an alkyl having 1-2 carbon atoms, and n1 and n2 are independently an integer of 1-3.

Abstract: Alight emitting device (10) includes a substrate (100) and a light emitting unit. The light emitting unit includes a first electrode (110), an organic layer (120), and a second electrode (130). The organic layer (120) is located between the first electrode (110) and the second electrode (130). The conductor (180) extends in the first direction (y direction) and at least a portion thereof is in contact with any surface of the first electrode (110). The conductor (180) contains conductive particles and includes a first portion (181) and a second portion (183). The second portion (183) is thicker than the first portion (181). The first portion (181) and the second portion (183) are aligned in the first direction and connected to each other.

Abstract: The present invention provides a cationic lipid which can be used for nucleic acid delivery to a cytoplasm and which is possible to solve the problem of physical stability of a lipid complex. This cationic lipid is a compound represented by the general formula (3) or a pharmaceutically acceptable salt thereof: wherein, L is an alkyl having 7-12 carbon atoms or an alkenyl having 7-12 carbon atoms, R is an alkyl having 1-2 carbon atoms, and n1 and n2 are independently an integer of 1-3.

Abstract: The present invention provides a cationic lipid which can be utilized for nucleic acid delivery into the cytoplasm. The cationic lipid of the present invention is, for example, a compound represented by the following Formula (1) or a pharmaceutically acceptable salt thereof.

Abstract: A light-emitting device (100) includes a substrate (110), a first electrode (120), an auxiliary electrode (124), an insular conductive layer (126), an insulating layer (170), an organic layer (130), and a second electrode (140). The first electrode (120) is formed over the substrate (110), and is formed using a transparent conductive material. The auxiliary electrode (124) is formed over the first electrode (120). The conductive layer (126) is formed over the first electrode (120), and is formed of the same material as that of the auxiliary electrode (124). The insulating layer (170) is formed over a portion of the first electrode (120), and covers the auxiliary electrode (124) and the conductive layer (126). The organic layer (130) is formed over the first electrode (120), and the second electrode (140) is formed over the organic layer (130).

Abstract: The present invention provides a cationic lipid which can be used for nucleic acid delivery to a cytoplasm and which is possible to solve the problem of physical stability of a lipid complex. This cationic lipid is a compound represented by the general formula (3) or a pharmaceutically acceptable salt thereof: wherein, L is an alkyl having 7-12 carbon atoms or an alkenyl having 7-12 carbon atoms, R is an alkyl having 1-2 carbon atoms, and n1 and n2 are independently an integer of 1-3.

Abstract: An organic EL device includes at least one insulating bank disposed on a translucent substrate, a translucent electrode in contact with the bank, an organic layer containing a light-emitting layer and formed on the translucent electrode, and a reflection electrode formed on the organic layer. The bank is made from a translucent dielectric material having a low refractive index that is equal to or less than that of the organic layer. The bank has a side face that is a slope inclined with respect to the translucent substrate. The side face has a concave surface shape that faces the light-emitting layer from a slope in contact with the light-emitting layer to a slope in contact with a portion of the organic layer in the vicinity of the reflection electrode.

Abstract: In an organic EL panel, a transparent conductive film, a functional layered body including at least one light-emitting layer, and an opposing electrode film are layered in this order on a substrate, and the light-emitting layer which overlaps the transparent conductive film and the opposing electrode film serves as a light-emitting portion. The organic EL panel has at least one auxiliary electrode that is formed on the substrate below the light-emitting portion and directly covered with the transparent conductive film. The transparent conductive film has a film thickness more than that of the auxiliary electrode and the side surface of the transparent conductive film is covered with the functional layered body.

Abstract: An organic semiconductor device of preventing invasion of hydrogen or hydrogen ion into the device and having a long-term reliability, and a method of manufacturing thereof are provided by giving a hydrogen absorbing layer which absorbs hydrogen or hydrogen ion, and which does not release the absorbed hydrogen or hydrogen ion. The organic semiconductor device comprises at least a substrate 10, a first electrodell, an organic functional component 12, a second layer 13, and a hydrogen absorbing layer 14 which absorbs hydrogen or hydrogen ion, and which does not release the absorbed hydrogen or hydrogen ion.

Abstract: The present invention is to provide a protective agent against damage of biological tissue caused by near-infrared rays which is capable of blocking the near-infrared rays from reaching not only skin but also deeper tissue than the skin tissue, preventing damage of such tissue caused by the near-infrared rays and preventing pathogenesis and development of various disease and acceleration of aging both of which are caused by the near-infrared rays, and a product using the protective agent. The protective agent against damage of biological tissue caused by near-infrared rays comprises a near-infrared ray penetration blocker that absorbs, reflects or scatters the near-infrared rays to prevent the damage of skin and deeper tissue than the skin in a living body caused by exposure with the near-infrared rays.

Abstract: Herein disclosed is a keyboard apparatus which comprises a plurality of keys each including a key holder, a scan board operative to input a key holder signal of each of the key-pushed actions of the keys, a memory for memorizing a key code relevant to the key holder, a plurality of numerical keys each having a key code inputted therein and outputting a key code signal indicative of the key-pushed actions of the numerical keys, a CPU having the key holder signal and the key code signal inputted therein, and state setting means for selectively setting two operation states respectively having the key holder signal and the key code signal outputted from the CPU.

Abstract: Herein disclosed is a keyboard apparatus which comprises a plurality of keys each including a key holder, a scan board operative to input a key holder signal of each of the key-pushed actions of the keys, a memory for memorizing a key code relevant to the key holder, a plurality of numerical keys each having a key code inputted therein and outputting a key code signal indicative of the key-pushed actions of the numerical keys, a CPU having the key holder signal and the key code signal inputted therein, and state setting means for selectively setting two operation states respectively having the key holder signal and the key code signal outputted from the CPU.