Patents by Inventor Yohichi Yasunami

Yohichi Yasunami has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Agents for suppressing damage to transplanted islets after islet transplantation
    Patent number: 8470316
    Abstract: The present inventors investigated anti-IL-6 receptor antibodies for their effect in suppressing damage to transplanted islets after islet transplantation. As a result, they found that anti-IL-6 receptor antibodies reduced damage to transplanted islets, improved islet survival, and corrected hyperglycemia in recipients. Further, they revealed that administration of the anti-IL-6 receptor antibodies of the present invention suppressed the production of inflammatory cytokines by infiltrating cells after transplantation. Specifically, the present inventors discovered for the first time that damage to transplanted islets after islet transplantation can be suppressed by using anti-IL-6 receptor antibodies according to the present invention.
    Type: Grant
    Filed: October 13, 2006
    Date of Patent: June 25, 2013
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventor: Yohichi Yasunami
  • Agent for Suppressing Rejection in Organ Transplantation Comprising Anti-HMGB-1 Antibody
    Publication number: 20100173277
    Abstract: An objective of the present invention is to provide effective methods for suppressing rejection in organ transplantation, in particular, pancreatic islet transplantation which is useful in treating diabetes. The present invention demonstrated that antibodies against HMGB-1 suppressed the rejection in pancreatic islet transplantation and promoted the survival of grafted pancreatic islets. Thus, the present invention provides agents that comprise an anti-HMGB-1 antibody for suppressing rejection in organ transplantation.
    Type: Application
    Filed: February 15, 2008
    Publication date: July 8, 2010
    Applicants: Fukuoka University, Kagoshima University, Shino-Test Corporation
    Inventors: Yohichi Yasunami, Ikuro Maruyama, Shingo Yamada
  • Agents for Suppressing Damage to Transplanted Islets After Islet Transplantation
    Publication number: 20090220499
    Abstract: The present inventors investigated anti-IL-6 receptor antibodies for their effect in suppressing damage to transplanted islets after islet transplantation. As a result, they found that anti-IL-6 receptor antibodies reduced damage to transplanted islets, improved islet survival, and corrected hyperglycemia in recipients. Further, they revealed that administration of the anti-IL-6 receptor antibodies of the present invention suppressed the production of inflammatory cytokines by infiltrating cells after transplantation. Specifically, the present inventors discovered for the first time that damage to transplanted islets after islet transplantation can be suppressed by using anti-IL-6 receptor antibodies according to the present invention.
    Type: Application
    Filed: October 13, 2006
    Publication date: September 3, 2009
    Applicant: FUKUOKA UNIVERSITY
    Inventor: Yohichi Yasunami