Patents by Inventor Yohji Ezure

Yohji Ezure has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5612203
    Abstract: Disclosed is a method for producing saccarides of definite chain length, such as glucose, maltose, malto-oligosaccharides and isomalto-oligosaccharides with a high purity. Saccharides such as starch, dextran and cellulose, and hydrolyzates thereof, are subjected to modification of the anomeric carbon at the reducing end of the molecule without modification of the non-reducing end of the molecule. The modification may be oxidation, for example by bromine to produce a carboxylic acid at the anomeric carbon, or amination, for example by phenylhydrazine to produce an osazone or osone of the saccharide. After modification, the modified saccharide can be adsorbed on an ion exchange resin and then repeatedly cleaved with a suitable enzyme, such as .beta.-amylase, to produce the desired saccharide of definite chain length.
    Type: Grant
    Filed: August 8, 1994
    Date of Patent: March 18, 1997
    Assignee: Nippon Shinyaku Co. Ltd.
    Inventors: Shigeaki Maruo, Noriyuke Tachikake, Yohji Ezure
  • Patent number: 5364794
    Abstract: A simplified process is provided for producing saccharides of definite chain length, such as glucose, maltose and maltooligosaccharides, each in an isolated state and with a high purity.The process comprises transferring a saccharide chain, using a saccharide chain transferase, from a saccharide chain source to a substance substantially separable from the saccharides mentioned above and treating the thus-obtained oligosaccharide with an enzyme capable of excising the saccharide chain of definite chain length in an exo manner.
    Type: Grant
    Filed: February 4, 1993
    Date of Patent: November 15, 1994
    Assignee: Nippon Shinyaku Company Limited
    Inventors: Yohji Ezure, Shigeaki Maruo, Katsunori Miyazaki, Naoyoshi Yamada
  • Patent number: 5256788
    Abstract: The present invention relates to stabilizing agents for enzymes which comprises an enzyme stabilizing amount of an N-substituted moranoline derivative of the formula (III): ##STR1## wherein R.sup.1 is phenyl lower alkynyl, phenoxy lower alkenyl or phenoxy lower alkynyl, wherein the phenyl moiety is unsubstituted, or a glucose oligomer thereof.
    Type: Grant
    Filed: February 5, 1990
    Date of Patent: October 26, 1993
    Assignee: Nippon Shinyaku Co. Ltd.
    Inventors: Yohji Ezure, Shigeaki Maruo, Hiroshi Yamashita, Katsunori Miyazaki, Makoto Sugiyama