Patents by Inventor Yohsuke Ohta

Yohsuke Ohta has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunassay of non-A, non-B hepatitis virus-related antigens, monoclonal antibodies for use therein, and hybridomas producing the antibodies
    Patent number: 5871904
    Abstract: This invention concerns a monoclonal antibody having binding specificity for an antigenic determinant site on core structural protein from Non-A,Non-B hepatitis virus (NANBV); a hybridoma cell line capable of producing the monoclonal antibody; a process for the preparation of the monoclonal antibody; an immunoassay of NANBV-related antigens by use of the monoclonal antibody; and a test kit for use in the immunoassay. The preferred monoclonal antibody is 5E3, 5F11, 515S or 1080S. The monoclonal antibody can specifically recognize the NANBV core structural protein in sera from patients with Non-A,Non-B hepatitis thereby being served extensively as an antibody in various immunological reagents for definitive diagnosis of Non-A, Non-B hepatitis.
    Type: Grant
    Filed: July 11, 1995
    Date of Patent: February 16, 1999
    Assignees: The Tokyo Metropolitan Institute of Medical Science, International Reagent Corporation, Tonen Corporation
    Inventors: Tomiko Kashiwakuma, Shintaro Yagi, Akira Hasegawa, Tadahiro Kajita, Yohsuke Ohta, Hiroyuki Mori
  • Anti-annexin-V monoclonal antibodies, and preparation and use thereof
    Patent number: 5767247
    Abstract: Using human annexin-V or human annexin-V plus dog annexin-V as antigen(s), hybridoma cell lines are prepared which are capable of producing anti-annexin-V monoclonal antibodies having a binding specificity to antigenic determinant site on annexin-V as antigenic protein and belonging to immunoglobulin G class. By the hybridoma cell lines are produced the anti-annexin-V monoclonal antibodies, with which a diagnostic agent is provided for diagnosis of myocardial infarction and angina pectoris.
    Type: Grant
    Filed: October 22, 1996
    Date of Patent: June 16, 1998
    Assignees: Noboru Kaneko, International Reagents Corporation
    Inventors: Noboru Kaneko, Ryuko Matsuda, Tadahiro Kajita, Yohsuke Ohta