Abstract: An oscillator 10 with a noise reduction function has a memory 80 that memorizes modulation data DM for performing the spread spectrum modulation input from an output terminal fout, a modulation signal output circuit 60 that generates a modulation signal SM from the modulation data DM memorized in the memory 80, and a mixer 53 that overlays the modulation signal SM on the control voltage VC of a voltage control oscillator (VCO) 54 of a PLL circuit 50, and it becomes possible to output a spread spectrum modulated output signal CLv under a specification desired by a user by memorizing in the memory 80 the modulation data DM that corresponds to the spread spectrum modulation the user tries to set.

Abstract: A monoclonal antibody specific to Nap was prepared by using a crude membrane fraction from a cell line which has a high affinity to Nef as an antigen. A cDNA clone which encodes Nap was obtained by screening a cDNA library of said cell line utilizing the specific antibody. The nucleotide sequence of this cDNA was elucidated whereupon the full amino acid sequences of human Nap was identified. Since the anti-Nap monoclonal antibody inhibits the binding of Nef to Nap, it can be used as a new therapeutic agent for AIDS. In addition, it can be applied for the diagnosis of AIDS by clarifying the relation between the expression of Nap and the development of AIDS. Nap can be utilized for binding experiments to Nef.

Abstract: This invention provides a voltage controlled oscillator that improves the linearity of frequency variable characteristics and increases the range of frequency that can be varied by a control voltage. A resistor circuit is connected between a piezoelectric resonator X and an oscillator circuit. The resistor circuit includes a plurality of oscillation-amplitude adjusting resistors Rs1 to Rsn and corresponding switches SW1 to SWn. The resistor circuit adjusts the amplitude of oscillation. When a control voltage Vc applied to a varactor Cv is at a low potential, clipping by a forward voltage of the varactor Cv is suppressed, and the frequency is linearly changed by the control voltage Vc within a range of a low potential to a high potential.

Abstract: A monoclonal antibody specific to Nap was prepared by using a crude membrane fraction from a cell line which has a high affinity to Nef as an antigen. A cDNA clone which encodes Nap was obtained by screening a cDNA library of said cell line utilizing the specific antibody. The nucleotide sequence of this cDNA was elucidated whereupon the full amino acid sequences of human Nap was identified. Since the anti-Nap monoclonal antibody inhibits the binding of Nef to Nap, it can be used as a new therapeutic agent for AIDS. In addition, it can be applied for the diagnosis of AIDS by clarifying the relation between the expression of Nap and the development of AIDS. Nap can be utilized for binding experiments to Nef.

Abstract: A method for prevention and treatment of viral infectious diseases using a medicament containing an effective amount of a compound of the formula ##STR1## where R.sup.1 is hydrogen or hydroxy, or acid addition salt thereof.

Abstract: To a light converter including an optical effect element is applied an electric input having an amplitude exceeding the linear region of the characteristic of the light converter. The number of the peaks of the output reaching a maximum amplitude is added to the magnitude of a peak of the output not reaching the maximum amplitude thereby measuring the magnitude of the input. Two or more light converters with differential or cumulative inputs may be used.