Abstract: A compound of the formula (I): wherein each symbol is as defined in the DESCRIPTION, or a pharmaceutically acceptable salt thereof has a superior Notch signal transduction inhibitory action, and is useful for preventing or treating various diseases involving Notch signal transduction.

Abstract: A compound of the formula (I): wherein each symbol is as defined in the DESCRIPTION, or a pharmaceutically acceptable salt thereof has a superior inhibitory activity on cancer cell proliferation.

Abstract: Provided are: a coating material for seeds that can be obtained by a simple treatment stage; and a coated seed that is coated with the aforesaid coating material, suffers from little physical damage and is almost free from growth inhibition. The coating material for seeds comprises as a major component a pulverized inorganic mineral powder. The coated seed is coated with the aforesaid coating material.

Abstract: The purpose of the present invention is: to produce a metabolite capable of improving drought tolerance of a plant to the same level as that achieved by abscisic acid, from a microorganism other than a microorganism that is known to be capable of producing abscisic acid; and to provide a method for improving drought tolerance of a plant using the metabolite. A method for producing a metabolite capable of improving drought tolerance using a microorganism, said method comprising culturing a microorganism that belongs to the genus Collimonas and has an ability of producing a metabolite capable of improving drought tolerance of a plant and then extracting the metabolite from a culture produced by the culturing.

Abstract: Provided are: a coating material for seeds that can be obtained by a simple treatment stage; and a coated seed that is coated with the aforesaid coating material, suffers from little physical damage and is almost free from growth inhibition. The coating material for seeds comprises as a major component a pulverized inorganic mineral powder. The coated seed is coated with the aforesaid coating material.

Abstract: A method for producing a cell extract having agricultural pest insecticidal capacity by culturing filamentous fungi having insecticidal capacity for an agricultural pest, and a method for insecticide produced by this production method. A method for producing a cell extract having agricultural pest insecticidal capacity provided with a step for culturing filamentous fungi in solid medium and obtaining a solid culture of the filamentous fungi, a step for culturing the filamentous fungi in liquid medium and obtaining a liquid culture of the filamentous fungi, a step for separating mycelia of the filamentous fungi from the liquid culture of the filamentous fungi, a step for mixing the liquid culture from which the mycelia have been removed and the solid culture and obtaining a mixed culture, and a step for extracting a spore solution of the filamentous fungi from this mixed culture.

Abstract: Provided are a novel cultivation method and a storage method that are suitable for storing bacteria belonging to the genus Collimonas for a long period of time. The cultivation method for bacteria belonging to the genus Collimonas is characterized in that bacteria belonging to the genus Collimonas are cultivated in a sealed state on a culture medium that includes a rice bran culture medium and/or a soy pulp culture medium. The storage method for bacteria belonging to the genus Collimonas is characterized in that the cultivated bacteria belonging to the genus Collimonas are stored at room temperature.

Abstract: The objective of the present invention is to provide a means for imparting control to agriculturally useful plants against diseases caused by a pathogenic filamentous fungus, pathogenic bacteria or pathogenic virus. The present invention relates to: a method for controlling plant diseases using a bacteria that belongs to the genus Collimonas and controls diseases caused by a pathogenic filamentous fungus, pathogenic bacteria or pathogenic virus; and a plant created from said method.

Abstract: To provide a method for inhibiting the proliferation of a plant pathogenic bacterium. A method for inhibiting the proliferation of a plant pathogenic bacterium, including culturing a microorganism having an ability to inhibit the proliferation of a plant pathogenic bacterium and belonging to the genus Collimonas, and seeding the cultured microorganism to a plant soil.

Abstract: To provide a method for inhibiting the proliferation of a plant pathogenic bacterium. A method for inhibiting the proliferation of a plant pathogenic bacterium, including culturing a microorganism having an ability to inhibit the proliferation of a plant pathogenic bacterium and belonging to the genus Collimonas, and seeding the cultured microorganism to a plant soil.

Abstract: Disclosed are a process for preparation of an optically active 7-substituted 3-(2-aminopropyl)indole compound and an intermediate therefor. In the above preparation process, 7-substituted indole is reacted with L- or DL-serine in the presence of a tryptophan-synthesizing enzyme originating in microorganisms to form corresponding 7-substituted L-tryptophan, and it is subjected, if necessary, to reduction, protection, exchange and elimination.

Abstract: Disclosed are a process for preparation of an optically active 7-substituted 3-(2-aminopropyl)indole compound and an intermediate therefor. In the above preparation process, 7-substituted indole is reacted with L- or DL-serine in the presence of a tryptophan-synthesizing enzyme originating in microorganisms to form corresponding 7-substituted L-tryptophan, and it is subjected, if necessary, to reduction, protection, exchange and elimination.