Patents by Inventor Yok-Lam Kwong

Yok-Lam Kwong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190046564
    Abstract: Methods for treating or preventing one or more symptoms of rheumatoid arthritis or other types of inflammatory arthritis involves administering a formulation containing an effective amount of arsenic trioxide to an affected patient. The arsenic trioxide formulation can be administered orally, for example, as a solution, suspension, syrup, emulsion, tablet, or capsule.
    Type: Application
    Filed: August 23, 2018
    Publication date: February 14, 2019
    Inventor: Yok-Lam Kwong
  • Patent number: 10092595
    Abstract: Methods for treating or preventing one or more symptoms of rheumatoid arthritis or other types of inflammatory arthritis involves administering a formulation containing an effective amount of arsenic trioxide to an affected patient. The arsenic trioxide formulation can be administered orally, for example, as a solution, suspension, syrup, emulsion, tablet, or capsule.
    Type: Grant
    Filed: May 18, 2010
    Date of Patent: October 9, 2018
    Assignee: The University of Hong Kong
    Inventor: Yok-Lam Kwong
  • Patent number: 8906422
    Abstract: The invention provides a method for treating cancers that are dependent on cyclin D1 for proliferation, survival, metastasis and differentiation, involving administering a composition containing an effective amount of arsenic trioxide to an affected patient. The arsenic trioxide can be administered orally, for example, as a solution, suspension, syrup, emulsion, tablet, or capsule. The composition can also contain one or more pharmaceutically acceptable carriers and/or excipients.
    Type: Grant
    Filed: October 11, 2007
    Date of Patent: December 9, 2014
    Assignee: The University of Hong Kong
    Inventor: Yok-Lam Kwong
  • Publication number: 20100291234
    Abstract: Methods for treating or preventing one or more symptoms of rheumatoid arthritis or other types of inflammatory arthritis involves administering a formulation containing an effective amount of arsenic trioxide to an affected patient. The arsenic trioxide formulation can be administered orally, for example, as a solution, suspension, syrup, emulsion, tablet, or capsule.
    Type: Application
    Filed: May 18, 2010
    Publication date: November 18, 2010
    Inventor: YOK-LAM KWONG
  • Patent number: 7521071
    Abstract: The present invention provides an oral formulation of arsenic trioxide (As2O3) for the treatment of a variety of hematological malignancies, including acute myeloid leukemia (AML) and acute promyelocytic leukemia (APL). The present invention also provides methods for making the oral arsenic trioxide formulation. Methods of using the oral arsenic trioxide formulation are also described.
    Type: Grant
    Filed: September 23, 2003
    Date of Patent: April 21, 2009
    Assignee: Versitech Limited
    Inventors: Cyrus Rustam Kumana, Yok-Lam Kwong
  • Publication number: 20080166425
    Abstract: The invention provides a method for treating cancers that are dependent on cyclin D1 for proliferation, survival, metastasis and differentiation, involving administering a composition containing an effective amount of arsenic trioxide to an affected patient. The arsenic trioxide can be administered orally, for example, as a solution, suspension, syrup, emulsion, tablet, or capsule. The composition can also contain one or more pharmaceutically acceptable carriers and/or excipients.
    Type: Application
    Filed: October 5, 2007
    Publication date: July 10, 2008
    Inventor: Yok-Lam Kwong
  • Publication number: 20080089951
    Abstract: It has been discovered that As2O3 suppresses tyrosine kinase receptors, in particular EGFR and IL-6R, by targeting RTKs to lysosomes and/or proteasome for degradation. This is the basis for the discovery that cancers dependent on RTKs for signaling, proliferation, survival, metastasis and differentiation can be treated with As2O3, preferably oral As2O3. Representative cancers include EGFR and cytokine dependent cancers, for example, head and neck squamous sarcomas and multiple myelomas, respectively.
    Type: Application
    Filed: October 11, 2007
    Publication date: April 17, 2008
    Inventor: Yok-Lam Kwong
  • Publication number: 20080089949
    Abstract: The invention provides a method for treating cancers that are dependent on cyclin D1 for proliferation, survival, metastasis and differentiation, involving administering effective amount of arsenic trioxide to an affected patient.
    Type: Application
    Filed: October 13, 2006
    Publication date: April 17, 2008
    Inventor: Yok-Lam Kwong
  • Publication number: 20080085931
    Abstract: The invention provides a method for treating cancers that are dependent on cyclin D1 for proliferation, survival, metastasis and differentiation, involving administering a composition containing an effective amount of arsenic trioxide to an affected patient. The arsenic trioxide can be administered orally, for example, as a solution, suspension, syrup, emulsion, tablet, or capsule. The composition can also contain one or more pharmaceutically acceptable carriers and/or excipients.
    Type: Application
    Filed: October 11, 2007
    Publication date: April 10, 2008
    Inventor: Yok-Lam Kwong
  • Publication number: 20040126434
    Abstract: The present invention provides an oral formulation of arsenic trioxide (As2O3) for the treatment of a variety of hematological malignancies, including acute myeloid leukemia (AML) and acute promyelocytic leukemia (APL). The present invention also provides methods for making the oral arsenic trioxide formulation. Methods of using the oral arsenic trioxide formulation are also described.
    Type: Application
    Filed: September 23, 2003
    Publication date: July 1, 2004
    Inventors: Cyrus Rustam Kumana, Yok-Lam Kwong