Abstract: Subsystems and methods for use in patch clamp systems are provided. For example, in certain embodiments, compensation circuitry is used to compensate for non-idealities present in the patch clamp system. The accuracy of this compensation may be verified by employing, for example, circuitry that models the patch clamp system.

Abstract: Subsystems and methods for use in patch clamp systems are provided. For example, in certain embodiments, compensation circuitry is used to compensate for non-idealities present in the patch clamp system. The accuracy of this compensation may be verified by employing, for example, circuitry that models the patch clamp system.

Abstract: Various embodiments of a multi-electrode holder are described. In one embodiment, the multi-electrode holder is employed to electrically connect a plurality of replaceable electrodes to a cable. In this embodiment, the multi-electrode holder includes a substrate, a plurality of independently actuatable contacts, and a connector, for connection to a cable, in electrical communication with the plurality of contacts. A plurality of channels may be formed in the substrate to receive at least two electrodes. In such a case, each contact may be aligned with a channel to retain an electrode disposed therein and to make electrical contact with such electrode. Alternatively, a plurality of electrode through-holes, for receiving electrodes, may be formed through the substrate. In this case, one end of a given electrode is retained by a contact and makes electrical contact therewith, while the other end of the electrode extends through an electrode through-hole.

Abstract: Subsystems and methods for use in patch clamp systems are provided. For example, in certain embodiments, compensation circuitry is used to compensate for non-idealities present in the patch clamp system. The accuracy of this compensation may be verified by employing, for example, circuitry that models the patch clamp system.

Abstract: Subsystems and methods for use in patch clamp systems are provided. For example, in certain embodiments, compensation circuitry is used to compensate for non-idealities present in the patch clamp system. The accuracy of this compensation may be verified by employing, for example, circuitry that models the patch clamp system.

Abstract: Subsystems and methods for use in patch clamp systems are provided. For example, in certain embodiments, compensation circuitry is used to compensate for non-idealities present in the patch clamp system. The accuracy of this compensation may be verified by employing, for example, circuitry that models the patch clamp system.

Abstract: Subsystems and methods for use in patch clamp systems are provided. For example, in certain embodiments, compensation circuitry is used to compensate for non-idealities present in the patch clamp system. The accuracy of this compensation may be verified by employing, for example, circuitry that models the patch clamp system.