Patents by Inventor Yoko Arai

Yoko Arai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220110916
    Abstract: The present invention provides a new antioxidant. An antioxidant of the present invention includes: a compound represented by the following formula (1) or a salt thereof: where in the formula (1), an A ring and a B ring may be the same or different and are a pyrazole ring having a substituent or a pyrazoline ring having a substituent, and L is a saturated or unsaturated hydrocarbon group.
    Type: Application
    Filed: December 18, 2019
    Publication date: April 14, 2022
    Applicant: Bioradical Research Institute Corp.
    Inventors: Keisuke Makino, Toshiyuki Arai, Yoko Arai, Masaichi Lee
  • Patent number: 10761087
    Abstract: The existent therapeutic drugs for CNV are merely pharmaceuticals for a symptomatic therapy, and therapeutic drugs for radical cure are strongly demanded. Also, a therapeutic drug for Dry AMD does not exist, and therapeutic drugs for radical cure are strongly demanded. The present invention provides a prophylactic and/or therapeutic agent for choroidal neovascularization, containing a compound having an activity of suppressing epithelial-mesenchymal transition in retinal pigment epithelial cells, as an active ingredient. Also, the present invention provides a drusen suppressor comprising a compound having an activity of suppressing epithelial-mesenchymal transition in retinal pigment epithelial cells, as an active ingredient.
    Type: Grant
    Filed: December 16, 2016
    Date of Patent: September 1, 2020
    Assignees: LINK GENOMICS, INC., ROHTO Pharmaceutical Co., Ltd.
    Inventors: Shinichiro Niwa, Dai Ogura, Hidemi Mizunuma, Yoko Arai, Takahiro Kurose, Yoshihiro Takai, Yoko Mitsuguchi, Mariyo Moriya
  • Patent number: 10323134
    Abstract: A particulate polyamide is provided. The particulate polyamide is porous and includes at least one of polyamide 4 and polyamide 3. In addition, the particulate polyamide has a particle diameter (d50) of from 10 ?m to 1,000 ?m and a particle diameter dispersion degree (Dv/Dn) of not greater than 3.0, wherein Dv represents the volume average particle diameter of the particulate polyamide, and Dn represents the number average particle diameter of the particulate polyamide.
    Type: Grant
    Filed: September 17, 2018
    Date of Patent: June 18, 2019
    Assignee: Ricoh Company, Ltd.
    Inventors: Yoko Arai, Atsumi Yamabe, Koichiro Oyama, Yasuo Kamada
  • Publication number: 20190016867
    Abstract: A particulate polyamide is provided. The particulate polyamide is porous and includes at least one of polyamide 4 and polyamide 3. In addition, the particulate polyamide has a particle diameter (d50) of from 10 ?m to 1,000 ?m and a particle diameter dispersion degree (Dv/Dn) of not greater than 3.0, wherein Dv represents the volume average particle diameter of the particulate polyamide, and Dn represents the number average particle diameter of the particulate polyamide.
    Type: Application
    Filed: September 17, 2018
    Publication date: January 17, 2019
    Applicant: RICOH COMPANY, LTD.
    Inventors: Yoko ARAI, Atsumi YAMABE, Koichiro OYAMA, Yasuo KAMADA
  • Publication number: 20180364216
    Abstract: The existent therapeutic drugs for CNV are merely pharmaceuticals for a symptomatic therapy, and therapeutic drugs for radical cure are strongly demanded. Also, a therapeutic drug for Dry AMD does not exist, and therapeutic drugs for radical cure are strongly demanded. The present invention provides a prophylactic and/or therapeutic agent for choroidal neovascularization, containing a compound having an activity of suppressing epithelial-mesenchymal transition in retinal pigment epithelial cells, as an active ingredient. Also, the present invention provides a drusen suppressor comprising a compound having an activity of suppressing epithelial-mesenchymal transition in retinal pigment epithelial cells, as an active ingredient.
    Type: Application
    Filed: December 16, 2016
    Publication date: December 20, 2018
    Inventors: Shinichiro Niwa, Dai Ogura, Hidemi Mizunuma, Yoko Arai, Takahiro Kurose, Yoshihiro Takai, Yoko Mitsuguchi, Mariyo Moriya
  • Patent number: 10138344
    Abstract: A particulate polyamide is provided. The particulate polyamide is porous and includes at least one of polyamide 4 and polyamide 3. In addition, the particulate polyamide has a particle diameter (d50) of from 10 ?m to 1,000 ?m and a particle diameter dispersion degree (Dv/Dn) of not greater than 3.0, wherein Dv represents the volume average particle diameter of the particulate polyamide, and Dn represents the number average particle diameter of the particulate polyamide.
    Type: Grant
    Filed: March 18, 2016
    Date of Patent: November 27, 2018
    Assignee: RICOH COMPANY, LTD.
    Inventors: Yoko Arai, Atsumi Yamabe, Koichiro Oyama, Yasuo Kamada
  • Patent number: 9587072
    Abstract: To provide a method for producing a polymer, which contains: bringing a ring-opening polymerizable monomer containing an amide bond, and a compressive fluid into contact with each other to melt or dissolve the ring-opening polymerizable monomer containing an amide bond, followed by allowing the ring-opening polymerizable monomer containing an amide bond to react through ring-opening polymerization in the presence of a basic organic metal catalyst and a cocatalyst, to thereby obtain a polymer product.
    Type: Grant
    Filed: May 23, 2014
    Date of Patent: March 7, 2017
    Assignee: Ricoh Company, Ltd.
    Inventors: Taichi Nemoto, Chiaki Tanaka, Yoko Arai, Satoshi Izumi, Yasuo Kamada
  • Publication number: 20160297927
    Abstract: A method for producing a polymer, which contains bringing a polymerizable monomer and a compressive fluid into contact with each other to melt or dissolve the polymerizable monomer, followed by polymerizing the polymerizable monomer in the presence of an electrophile serving as an initiator.
    Type: Application
    Filed: November 18, 2014
    Publication date: October 13, 2016
    Inventors: Satoshi IZUMI, Taichi NEMOTO, Yoko ARAI, Takayuki SHIMIZU, Shigehiro HIRANO, Chiaki TANAKA
  • Publication number: 20160280849
    Abstract: Provided is a polymer product having a branched chain made of polyester, and a weight average molecular weight of 200,000 or greater when measured by gel permeation chromatography.
    Type: Application
    Filed: November 18, 2014
    Publication date: September 29, 2016
    Inventors: Yasuo KAMADA, Taichi NEMOTO, Yoko ARAI, Satoshi IZUMI
  • Publication number: 20160272776
    Abstract: A particulate polyamide is provided. The particulate polyamide is porous and includes at least one of polyamide 4 and polyamide 3. In addition, the particulate polyamide has a particle diameter (d50) of from 10 ?m to 1,000 ?m and a particle diameter dispersion degree (Dv/Dn) of not greater than 3.0, wherein Dv represents the volume average particle diameter of the particulate polyamide, and Dn represents the number average particle diameter of the particulate polyamide.
    Type: Application
    Filed: March 18, 2016
    Publication date: September 22, 2016
    Applicant: RICOH COMPANY, LTD.
    Inventors: Yoko ARAI, Atsumi YAMABE, Koichiro OYAMA, Yasuo KAMADA
  • Patent number: 9447228
    Abstract: A polymer production apparatus, including: supplying unit containing first supplying unit to supply raw materials containing monomer, and second supplying unit to supply compressive fluid; contacting unit to bring the monomer and the compressive fluid into contact together; and outlet configured to discharge reaction product of the monomer, wherein reaction unit is provided between the contacting unit and the outlet, where the reaction unit is to pass the monomer from the contacting unit side to the outlet side, while allowing the monomer to carry out a polymerization reaction in the presence of the compressive fluid, and wherein the reaction unit contains circulation unit containing first pipe and second pipe, where a fluid is passed through the first pipe from the contacting unit side to the outlet side, and the second pipe is to return the fluid from return port provided upstream extrusion unit to inlet provided upstream the return port.
    Type: Grant
    Filed: November 17, 2014
    Date of Patent: September 20, 2016
    Assignee: Ricoh Company, Ltd.
    Inventors: Yuuichi Satoh, Satoshi Izumi, Taichi Nemoto, Yoko Arai, Yasuo Kamada, Chiaki Tanaka
  • Publication number: 20160264686
    Abstract: A method for producing a polymer, which contains: bringing a monomer containing a vinyl bond into contact with a compressive fluid and melting or dissolving the monomer containing a vinyl bond, followed by carrying out addition polymerization of the monomer containing a vinyl bond in the presence of an initiator.
    Type: Application
    Filed: November 18, 2014
    Publication date: September 15, 2016
    Inventors: Taichi NEMOTO, Yoko ARAI, Satoshi IZUMI, Shigehiro HIRANO, Takayuki SHIMIZU, Chiaki TAKANA
  • Publication number: 20160194445
    Abstract: To provide a method for producing a polymer, which contains: bringing a ring-opening polymerizable monomer containing an amide bond, and a compressive fluid into contact with each other to melt or dissolve the ring-opening polymerizable monomer containing an amide bond, followed by allowing the ring-opening polymerizable monomer containing an amide bond to react through ring-opening polymerization in the presence of a basic organic metal catalyst and a cocatalyst, to thereby obtain a polymer product.
    Type: Application
    Filed: May 23, 2014
    Publication date: July 7, 2016
    Applicant: Ricoh Company, Ltd.
    Inventors: Taichi NEMOTO, Chiaki TANAKA, Yoko ARAI, Satoshi IZUMI, Yasuo KAMADA
  • Publication number: 20160083512
    Abstract: To provide a polymer product, which contains aliphatic polycarbonate, wherein an oxide unit content in the aliphatic polycarbonate is 20 mol % or less, and wherein a monomer content in the aliphatic polycarbonate is 500 ppm or less, where the monomer is a monomer that is a base of the aliphatic polycarbonate.
    Type: Application
    Filed: April 25, 2014
    Publication date: March 24, 2016
    Applicant: RICOH COMPANY, LTD.
    Inventors: Yasuo KAMADA, Taichi NEMOTO, Yoko ARAI, Satoshi IZUMI, Chiaki TANAKA
  • Publication number: 20150376363
    Abstract: Provided is a porous material made of at least an aliphatic polyester resin or an aliphatic polycarbonate resin, and having a porosity of 70% or higher, wherein a polystyrene equivalent weight average molecular weight of the resin measured by gel permeation chromatography is 300,000 or greater.
    Type: Application
    Filed: January 20, 2014
    Publication date: December 31, 2015
    Applicant: RICOH COMPANY, LTD.
    Inventors: Masaki WATANABE, Chiaki TANAKA, Yoko ARAI, Satoshi IZUMI, Taichi NEMOTO, Takayuki SHIMIZU, Shigehiro HIRANO
  • Publication number: 20150361213
    Abstract: Provided is a polymer product, in which the weight average molecular weight measured by gel permeation chromatography is 250,000 or greater and the content of residual ring-opening-polymerizable monomer is 100 ppm by mass or greater but less than 1,000 ppm by mass, or a polymer product, in which the content of residual ring-opening-polymerizable monomer is from 1,000 ppm by mass to 20,000 ppm by mass and the yellow index (YI) value is 15 or less.
    Type: Application
    Filed: January 20, 2014
    Publication date: December 17, 2015
    Inventors: Yasuo KAMADA, Taichi NEMOTO, Satoshi IZUMI, Yoko ARAI, Chiaki TANAKA, Yukihiro IMANAGA
  • Publication number: 20150353677
    Abstract: To provide a polymer production apparatus, which contains: a first supply unit configured to supply raw materials including a monomer; a second supply unit configured to supply a compressive fluid; a contact unit configured to bring the monomer into contact with the compressive fluid; and a reaction unit configured to allow the monomer, which has been brought into contact with the compressive fluid, to react in the presence of the compressive fluid, wherein the reaction unit contains one, or two or more extrusion devices, and one, or two or more stirring devices.
    Type: Application
    Filed: January 27, 2014
    Publication date: December 10, 2015
    Applicant: Ricoh Company, Ltd.
    Inventors: Satoshi IZUMI, Taichi NEMOTO, Yoko ARAI, Yasuo KAMADA, Chiaki TANAKA
  • Publication number: 20150329668
    Abstract: An aliphatic polyester having a number-average molecular weight of from 500,000 to 2,000,000 includes an ester bonding site and an amide bonding site. The content of the amide bonding site is from 1×10?3% to 1×10?1% by mol based on total weight of the ester bonding site and the amide bonding site.
    Type: Application
    Filed: April 29, 2015
    Publication date: November 19, 2015
    Inventors: Kaori Miyahara, Taichi Nemoto, Yoko Arai, Susumu Chiba, Shohta Kobayashi, Yoshihito Shimada
  • Publication number: 20150322201
    Abstract: Provided is a polymer product that has a melting point difference (Tm1?Tm0) of 3° C. or more between a polymer melting point Tm0 before it is heated and a polymer melting point Tm1 after it is heated under a nitrogen atmosphere for 60 minutes at a temperature that is higher than the highest polymer melting point by from 10° C. to 50° C.
    Type: Application
    Filed: January 27, 2014
    Publication date: November 12, 2015
    Applicant: RICOH COMPANY, LTD.
    Inventors: Yoko ARAI, Taichi NEMOTO, Yasuo KAMADA, Satoshi IZUMI, Chiaki TANAKA, Yukihiro IMANAGA, Tatsuya MORITA
  • Patent number: 9110438
    Abstract: A disclosed flange member includes a press-fitted portion to be press-fitted in an axial end-opening portion of a hollow and cylindrical sleeve member; an axle opening portion including an axle opening into which a shaft member is inserted when the press-fitted portion is press-fitted in the end-opening portion; and a linking portion extending in a direction parallel to a circular cross section of the sleeve member and connecting the axle opening portion to the press-fitted portion. The linking portion includes a stress-absorbing portion that is deformed so as to absorb stress to which an outer peripheral surface of the press-fitted portion is subjected upon contact with an inner peripheral surface of the sleeve member when the press-fitted portion is press-fitted in the end-opening portion, thus preventing the stress from being transmitted to the axle opening portion via the linking portion.
    Type: Grant
    Filed: November 10, 2011
    Date of Patent: August 18, 2015
    Assignee: RICOH COMPANY, LTD.
    Inventors: Daisuke Kubo, Keiichi Yano, Akira Nakamura, Yoko Arai