Patents by Inventor Yoko Makino
Yoko Makino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240033745Abstract: This biochemical analysis device has a configuration in which a reaction unit is installed on a device body, the reaction unit including: a test tube unit having a plurality of test tubes or a test tube unit in which a plurality of test tubes can be installed; a cassette guide; and a cassette box that allows attachment/detachment of the cassette guide. The cassette guide includes a flange part, a ventilation opening provided in the flange part, and a test tube insertion part provided to the flange part. The test tube insertion part is a closed structure, the flange part is installed on the upper surface section of the cassette box, and the ventilation opening suctions air above the flange part via negative pressure generated by an internal space of the cassette box.Type: ApplicationFiled: August 31, 2020Publication date: February 1, 2024Inventors: Bohao CHENG, Hayato SHIMIZU, Toshiki YAMAGATA, Masashi SHIBAHARA, Yoko MAKINO
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Publication number: 20240033741Abstract: The present invention provides a thermal cycler capable of rapidly and efficiently heating and cooling a reaction liquid. The thermal cycler according to the present invention comprises: a temperature control block where a reaction vessel can be installed, a thermoelectric conversion unit capable of heating and cooling, a temperature sensor that measures the temperature of the temperature control block, an insulating substrate that is in contact at one surface with the thermoelectric conversion unit, and a heat radiating unit that is provided on the other surface of the insulating substrate and serves for discharging the heat of the thermoelectric conversion unit to the outside, wherein the temperature control block is heated and cooled by controlling a current or voltage supplied to the thermoelectric conversion unit on the basis of the temperature of the temperature adjustment block measured by the temperature sensor.Type: ApplicationFiled: December 18, 2020Publication date: February 1, 2024Applicant: Hitachi High-Tech CorporationInventors: Nobuyuki ISOSHIMA, Tatsuya KOBARI, Masashi SHIBAHARA, Toshiki YAMAGATA, Yoko MAKINO, Wataru SATOH
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Publication number: 20230366901Abstract: The purpose of the present invention is to provide an automatic analysis device with excellent workability while removing dew condensation water that is generated on an inner wall of a reagent storage cabinet. To this end, the present invention comprises a reagent storage cabinet for storing a plurality of reagent containers, wherein the reagent storage cabinet has: a reagent jacket that rotates while holding the reagent containers; a housing that accommodates the reagent jacket; and a lid part that covers the housing from above and that has formed therein a dispensing hole for dispensing the reagent inside the reagent containers, and a sliding contact mechanism, which is capable of switching between a state of being in contact with an inner wall surface of the housing and a state of being spaced away from the inner wall surface of the housing, is provided to the reagent jacket.Type: ApplicationFiled: September 15, 2020Publication date: November 16, 2023Inventors: Yoko MAKINO, Masashi SHIBAHARA, Toshiki YAMAGATA
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Publication number: 20230347352Abstract: This reaction unit, which is used in a genetic testing apparatus, is provided with a test tube unit which has multiple test tubes, or a test tube unit where multiple test tubes can be arranged, and a cassette stand where the test tube unit can be arranged; a ventilation opening is provided on the upper surface of the cassette stand, and by means of an exhaust fan installed in or connected to a lateral surface of the cassette stand, the internal space of the cassette stand is brought to a negative pressure, which generates a downward stream of air towards the ventilation hole from above the test tubes. In this way, the gene testing apparatus can prevent cross-contamination between different samples, and can improve test accuracy.Type: ApplicationFiled: July 2, 2020Publication date: November 2, 2023Applicant: Hitachi High-Tech CorporationInventors: Bohao CHENG, Hayato SHIMIZU, Toshiki YAMAGATA, Yoko MAKINO, Masashi SHIBAHARA
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Publication number: 20210237089Abstract: A thermal cycler 160 includes: a support block 3 configured to support a reaction vessel 2; a Peltier element 5 thermally connected to the support block 3 and configured to adjust a temperature of a sample solution 1 stored in the reaction vessel 2 by heating/cooling the support block 3; a temperature sensor 4 configured to measure a temperature of the support block 3; and a temperature adjusting unit 230 configured to control a current and a voltage supplied to the Peltier element 5 based on the temperature of the support block 3 measured by the temperature sensor 4. As the reaction vessel 2, a reaction vessel 2 including a conical portion which opens at an upper portion 21 and tapers toward a lower portion is used, and the Peltier element 5 is arranged so as to be parallel to a conical generatrix 23 portion of the reaction vessel 2.Type: ApplicationFiled: September 28, 2018Publication date: August 5, 2021Applicant: HITACHI HIGH-TECH CORPORATIONInventors: Hayato SHIMIZU, Toshiki YAMAGATA, Yoko MAKINO, Nobutaka KUMAZAKI
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Patent number: 6329125Abstract: Alkali-developable, chemically amplified resist composition which comprises an alkali-insoluble compound having a structural unit containing a protected alkali-soluble group in which unit a protective moiety of said protected alkali-soluble group contains an alicyclic hydrocarbon group having bonded to a carbon atom thereof a —CH2—R1′ group wherein R1′ is methyl, ethyl, propyl or isopropyl, and said alkali-soluble group is cleaved upon action of an acid generated from a photoacid generator used in combination with said compound, thereby releasing said protective moiety from the alkali-soluble group and converting said compound to an alkali-soluble one, and a photoacid generator capable of being decomposed upon exposure to a patterning radiation to thereby produce an acid capable of causing cleavage of said protective moiety.Type: GrantFiled: December 19, 2000Date of Patent: December 11, 2001Assignee: Fujitsu LimitedInventors: Satoshi Takechi, Akiko Kotachi, Koji Nozaki, Ei Yano, Keiji Watanabe, Takahisa Namiki, Miwa Igarashi, Yoko Makino, Makoto Takahashi
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Publication number: 20010003640Abstract: Alkali-developable, chemically amplified resist composition which comprises an alkali-insoluble compound having a structural unit containing a protected alkali-soluble group in which unit a protective moiety of said protected alkali-soluble group contains an alicyclic hydrocarbon group having bonded to a carbon atom thereof a —CH2—R1′ group wherein R1′ is methyl, ethyl, propyl or isopropyl, and said alkali-soluble group is cleaved upon action of an acid generated from a photoacid generator used in combination with said compound, thereby releasing said protective moiety from the alkali-soluble group and converting said compound to an alkali-soluble one, and a photoacid generator capable of being decomposed upon exposure to a patterning radiation to thereby produce an acid capable of causing cleavage of said protective moiety.Type: ApplicationFiled: December 19, 2000Publication date: June 14, 2001Applicant: FUJITSU LIMITEDInventors: Satoshi Takechi, Akiko Kotachi, Koji Nozaki, Ei Yano, Keiji Watanabe, Takahisa Namiki, Miwa Igarashi, Yoko Makino, Makoto Takahashi
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Patent number: 6200725Abstract: Alkali-developable, chemically amplified resist composition which comprises an alkali-insoluble compound having a structural unit containing a protected alkali-soluble group in which unit a protective moiety of said protected alkali-soluble group contains an alicyclic hydrocarbon group having bonded to a carbon atom thereof a —CH2—R1′ group wherein R1′ is methyl, ethyl, propyl or isopropyl, and said alkali-soluble group is cleaved upon action of an acid generated from a photoacid generator used in combination with said compound, thereby releasing said protective moiety from the alkali-soluble group and converting said compound to an alkali-soluble one, and a photoacid generator capable of being decomposed upon exposure to a patterning radiation to thereby produce an acid capable of causing cleavage of said protective moiety.Type: GrantFiled: November 28, 1997Date of Patent: March 13, 2001Assignee: Fujitsu LimitedInventors: Satoshi Takechi, Akiko Kotachi, Koji Nozaki, Ei Yano, Keiji Watanabe, Takahisa Namiki, Miwa Igarashi, Yoko Makino, Makoto Takahashi